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The map label for this gene is mraY [H]

Identifier: 161870656

GI number: 161870656

Start: 1770477

End: 1771559

Strand: Reverse

Name: mraY [H]

Synonym: NMCC_1726

Alternate gene names: 161870656

Gene position: 1771559-1770477 (Counterclockwise)

Preceding gene: 161870657

Following gene: 161870655

Centisome position: 82.27

GC content: 54.76

Gene sequence:

>1083_bases
ATGTTTTTATGGCTCGCACATTTCAGCAACTGGTTAACCGGTCTGAATATTTTTCAATACACCACATTCCGCGCCGTCAT
GGCGGCGTTGACCGCCTTAGCGTTTTCCCTGATGTTCGGCCCGTGGACGATACGCAGGCTGACCGCGCTCAAATGCGGGC
AGGCAGTGCGTACCGACGGTCCGCAAACCCACCTCGTCAAAAACGGCACGCCGACGATGGGCGGTTCGCTGATTCTGACC
GCCATTACCGTGTCCACCCTGTTGTGGGGCAACTGGGCAAACCCGTATATCTGGATTCTCTTGGGCGTATTGCTCGCCAC
GGGCGCACTCGGTTTTTACGACGACTGGCGCAAAGTCGTCTATAAAGACCCCAACGGCGTGTCCGCCAAATTCAAAATGG
TGTGGCAGTCAAGCGTTGCCATTATCGCCGGTTTGGCATTGTTTTACCTTGCCGCCAATTCCGCCAACAATATTTTGATT
GTCCCGTTCTTCAAACAAATCGCCCTGCCGCTGGGCGTGGTCGGCTTTTTGGTGTTGTCTTACCTGACCATCGTCGGCAC
ATCCAATGCCGTCAACCTCACCGACGGCTTGGACGGCCTTGCGACCTTCCCCGTCGTCCTCGTTGCCGCCGGCCTCGCCA
TTTTCGCCTACGTCAGCGGACACTACCAATTTTCCCAATACCTCCAGCTTCCCTATGTCGCCGGCGCGAACGAAGTCGCT
ATATTCTGCACCGCCATGTGCGGCGCGTGCCTCGGTTTCTTGTGGTTTAACGCCTATCCCGCGCAAGTCTTTATGGGCGA
TGTCGGCGCATTGGCATTGGGTGCCGCGCTCGGTACCGTTGCCGTCATCGTCCGCCAAGAGTTTGTTTTAGTGATTATGG
GCGGTCTGTTCGTCGTCGAAGCTGTGTCCGTTATGCTTCAGGTCGGCTGGTATAAGAAAACCAAAAAACGCATTTTCCTG
ATGGCACCCATCCACCACCACTACGAACAAAAAGGCTGGAAAGAAACCCAAGTTGTCGTCCGCTTTTGGATTATCACCAT
CGTCTTGGTATTGATCGGCTTGAGTACCCTCAAAATCCGCTGA

Upstream 100 bases:

>100_bases
TGAGCACCTTAGAGAATCGTTCTCTTTGAGCTAAGGCGAGGCAACGCCGTACTGGTTTTTGTTAATCCACTATAACGACA
AAACAAAAAAAGGAAGCCCC

Downstream 100 bases:

>100_bases
ACCTATGCCGTCTGAACATCTTTCAGACGGCATTTGAACGCGCAATAAACCTGCGGCGACAATCCGCCCAGCCCTATCGT
TAACGGCGGCTTATACTAAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MFLWLAHFSNWLTGLNIFQYTTFRAVMAALTALAFSLMFGPWTIRRLTALKCGQAVRTDGPQTHLVKNGTPTMGGSLILT
AITVSTLLWGNWANPYIWILLGVLLATGALGFYDDWRKVVYKDPNGVSAKFKMVWQSSVAIIAGLALFYLAANSANNILI
VPFFKQIALPLGVVGFLVLSYLTIVGTSNAVNLTDGLDGLATFPVVLVAAGLAIFAYVSGHYQFSQYLQLPYVAGANEVA
IFCTAMCGACLGFLWFNAYPAQVFMGDVGALALGAALGTVAVIVRQEFVLVIMGGLFVVEAVSVMLQVGWYKKTKKRIFL
MAPIHHHYEQKGWKETQVVVRFWIITIVLVLIGLSTLKIR

Sequences:

>Translated_360_residues
MFLWLAHFSNWLTGLNIFQYTTFRAVMAALTALAFSLMFGPWTIRRLTALKCGQAVRTDGPQTHLVKNGTPTMGGSLILT
AITVSTLLWGNWANPYIWILLGVLLATGALGFYDDWRKVVYKDPNGVSAKFKMVWQSSVAIIAGLALFYLAANSANNILI
VPFFKQIALPLGVVGFLVLSYLTIVGTSNAVNLTDGLDGLATFPVVLVAAGLAIFAYVSGHYQFSQYLQLPYVAGANEVA
IFCTAMCGACLGFLWFNAYPAQVFMGDVGALALGAALGTVAVIVRQEFVLVIMGGLFVVEAVSVMLQVGWYKKTKKRIFL
MAPIHHHYEQKGWKETQVVVRFWIITIVLVLIGLSTLKIR
>Mature_360_residues
MFLWLAHFSNWLTGLNIFQYTTFRAVMAALTALAFSLMFGPWTIRRLTALKCGQAVRTDGPQTHLVKNGTPTMGGSLILT
AITVSTLLWGNWANPYIWILLGVLLATGALGFYDDWRKVVYKDPNGVSAKFKMVWQSSVAIIAGLALFYLAANSANNILI
VPFFKQIALPLGVVGFLVLSYLTIVGTSNAVNLTDGLDGLATFPVVLVAAGLAIFAYVSGHYQFSQYLQLPYVAGANEVA
IFCTAMCGACLGFLWFNAYPAQVFMGDVGALALGAALGTVAVIVRQEFVLVIMGGLFVVEAVSVMLQVGWYKKTKKRIFL
MAPIHHHYEQKGWKETQVVVRFWIITIVLVLIGLSTLKIR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=56.5096952908587, Blast_Score=400, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39390; Mature: 39390

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLWLAHFSNWLTGLNIFQYTTFRAVMAALTALAFSLMFGPWTIRRLTALKCGQAVRTDG
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHCCCC
PQTHLVKNGTPTMGGSLILTAITVSTLLWGNWANPYIWILLGVLLATGALGFYDDWRKVV
CCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHE
YKDPNGVSAKFKMVWQSSVAIIAGLALFYLAANSANNILIVPFFKQIALPLGVVGFLVLS
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHH
YLTIVGTSNAVNLTDGLDGLATFPVVLVAAGLAIFAYVSGHYQFSQYLQLPYVAGANEVA
HHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEECCCCHHH
IFCTAMCGACLGFLWFNAYPAQVFMGDVGALALGAALGTVAVIVRQEFVLVIMGGLFVVE
HHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSVMLQVGWYKKTKKRIFLMAPIHHHYEQKGWKETQVVVRFWIITIVLVLIGLSTLKIR
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure
MFLWLAHFSNWLTGLNIFQYTTFRAVMAALTALAFSLMFGPWTIRRLTALKCGQAVRTDG
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHCCCC
PQTHLVKNGTPTMGGSLILTAITVSTLLWGNWANPYIWILLGVLLATGALGFYDDWRKVV
CCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHE
YKDPNGVSAKFKMVWQSSVAIIAGLALFYLAANSANNILIVPFFKQIALPLGVVGFLVLS
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHH
YLTIVGTSNAVNLTDGLDGLATFPVVLVAAGLAIFAYVSGHYQFSQYLQLPYVAGANEVA
HHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEECCCCHHH
IFCTAMCGACLGFLWFNAYPAQVFMGDVGALALGAALGTVAVIVRQEFVLVIMGGLFVVE
HHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSVMLQVGWYKKTKKRIFLMAPIHHHYEQKGWKETQVVVRFWIITIVLVLIGLSTLKIR
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA