Click here to switch to the map view.

The map label for this gene is aspS [H]

Identifier: 161870607

GI number: 161870607

Start: 1706400

End: 1708208

Strand: Reverse

Name: aspS [H]

Synonym: NMCC_1676

Alternate gene names: 161870607

Gene position: 1708208-1706400 (Counterclockwise)

Preceding gene: 161870608

Following gene: 161870606

Centisome position: 79.33

GC content: 53.01

Gene sequence:

>1809_bases
ATGCGTACCAACTATTGCGGCCTGATCAGCGAGCAATACTTAGACCAAACCGTTACCGTCAAAGGCTGGGTACACCGCCG
GCGCGACCACGGCGGTGTGATTTTTATCGACCTGCGCGACCGCGAAGGCATCGTCCAAGTCGTGATCGATCCCGATACGC
CCGAAGCGTTTGCCGCTGCCGATTCCGCCCGTAACGAATATGTTTTGAGCATTACCGGCCGCGTACGCAACCGTCCCGAA
GGTACGACCAACGACAAAATGATTTCCGGCAAAATCGAGATTCTTGCCAAAGAAATCGAAGTCTTGAACGCTGCCGCTAC
ACCTCCGTTCCAAATCGACGATGAAAATATCAGCGAAAACGTTCGCCTGACCAACCGCGTTATCGACTTGCGCCGTCCTG
CCATGCAACGCAACCTGCGCCTGCGTTACCAAGTTGCTATGGGCGTTCGCCGCTACTTGGACGCACAAGGCTTTATCGAC
ATCGAAACCCCAATGCTGACCCGCTCCACGCCTGAAGGCGCGCGCGACTACCTCGTGCCGAGCCGCGTTCATCCGGGCGA
GTTTTTCGCTCTGCCGCAATCTCCGCAATTGTTCAAACAACTGTTGATGGTTGCTGGTTTCGACCGTTACTACCAAATCA
CCAAATGTTTCCGTGACGAAGACTTGCGTGCCGACCGTCAACCTGAATTCACTCAAATCGACTTGGAAACCTCGTTCTTG
AACGAGGATGAAATCATGGACATCACCGAAGGTATGGCGAAACAAGTCTTCAAAGATGCTTTAAACGTAGATTTAGGCGA
CTTCCCGCGTATGCCTTACGCCGAAGCCATGTTCTACTACGGCTCTGACAAACCGGATATGCGTATCAACTTGAAATTTA
CCGAGTTGACCGACCTGATGAAAACGGAAGAATTCAAAGTCTTCCGTGGCGCGGCAGATATGAAAGGCGGCCGTGTAGTC
GCCCTGCGCGTACCGAACGGCGCAAAATTCAGCCGCAAAGAAATCGACGAATACACTAAATTTGTCGGCATCTACGGCGC
GAAAGGTCTGGCATACATCAAAGTAAACGATGTGGGCAACCTCTCAAACGGCGAAGACAGCGGCCTGCAATCTCCAATCG
TAAAATTCCTGTCTGAGAATGCCCTGAAAGAAATCATCGAGCGTACCGGCGCACAAAACGGCGATATTATTTTCTTCGGT
GCGGACAAAACCAAAGTTGTGAACGAAGCCATCGGCGCATTGCGTATCAAAGTCGGCTTGGAACACGGCAAAGACAACGG
CTACTTCACAGACGAATGGAAACCTTTGTGGGTTGTCGATTTCCCAATGTTCGAATACGACGAAGAAGCCGACCGCTACG
TTGCCGTACACCATCCGTTTACCGCGCCTAAAGAAGGTCATGAAGACCTGATGGTTTCCGACCCTGCAAACTGCCTGGCC
CGTGCCTACGACATGGTATTGAACGGCTGGGAAATCGGCGGCGGCTCTATCCGTATCCACCGTGCAGACGTACAAGAGAA
AGTGTTTGCCGCGCTGAAAATCAGCCCTGAAGAGCAACAAGAGAAATTCGGCTTCCTCTTGGACAACCTGAAATTCGGTG
CGCCTCCTCACGGCGGCCTTGCATTCGGCCTCGACCGTTTGGTTACCCTGATGACCGGCGCCGAATCTATCCGCGACGTG
ATTGCCTTCCCGAAAACACAACGTGCCCAATGCCTGCTGACCAACGCGCCCAACAGCGTGGACGACAAGCAGTTGCGTGA
ATTGAGCCTGCGCCTGCGCCAAAAGGCGGCTGAAACCAAAGAAGCATAA

Upstream 100 bases:

>100_bases
ACCTATGCCGTCTGAAAAGGCGGATTTGCCCGAACAACAATAAAGCCGCCGTTCAGACGGCATTTTCTGTTTTCAGTTTA
AATTAATAAAAGGTGATTTT

Downstream 100 bases:

>100_bases
GGAAAACGGAGCCGTTTGACGGCTCTGTTTTTTTCAGACGGCATTTACGCTTCTTGACTTCCCTCTAATTCAAACCTAAT
TTTGCTGTGTTTTAATGGCG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPDTPEAFAAADSARNEYVLSITGRVRNRPE
GTTNDKMISGKIEILAKEIEVLNAAATPPFQIDDENISENVRLTNRVIDLRRPAMQRNLRLRYQVAMGVRRYLDAQGFID
IETPMLTRSTPEGARDYLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDLETSFL
NEDEIMDITEGMAKQVFKDALNVDLGDFPRMPYAEAMFYYGSDKPDMRINLKFTELTDLMKTEEFKVFRGAADMKGGRVV
ALRVPNGAKFSRKEIDEYTKFVGIYGAKGLAYIKVNDVGNLSNGEDSGLQSPIVKFLSENALKEIIERTGAQNGDIIFFG
ADKTKVVNEAIGALRIKVGLEHGKDNGYFTDEWKPLWVVDFPMFEYDEEADRYVAVHHPFTAPKEGHEDLMVSDPANCLA
RAYDMVLNGWEIGGGSIRIHRADVQEKVFAALKISPEEQQEKFGFLLDNLKFGAPPHGGLAFGLDRLVTLMTGAESIRDV
IAFPKTQRAQCLLTNAPNSVDDKQLRELSLRLRQKAAETKEA

Sequences:

>Translated_602_residues
MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPDTPEAFAAADSARNEYVLSITGRVRNRPE
GTTNDKMISGKIEILAKEIEVLNAAATPPFQIDDENISENVRLTNRVIDLRRPAMQRNLRLRYQVAMGVRRYLDAQGFID
IETPMLTRSTPEGARDYLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDLETSFL
NEDEIMDITEGMAKQVFKDALNVDLGDFPRMPYAEAMFYYGSDKPDMRINLKFTELTDLMKTEEFKVFRGAADMKGGRVV
ALRVPNGAKFSRKEIDEYTKFVGIYGAKGLAYIKVNDVGNLSNGEDSGLQSPIVKFLSENALKEIIERTGAQNGDIIFFG
ADKTKVVNEAIGALRIKVGLEHGKDNGYFTDEWKPLWVVDFPMFEYDEEADRYVAVHHPFTAPKEGHEDLMVSDPANCLA
RAYDMVLNGWEIGGGSIRIHRADVQEKVFAALKISPEEQQEKFGFLLDNLKFGAPPHGGLAFGLDRLVTLMTGAESIRDV
IAFPKTQRAQCLLTNAPNSVDDKQLRELSLRLRQKAAETKEA
>Mature_602_residues
MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPDTPEAFAAADSARNEYVLSITGRVRNRPE
GTTNDKMISGKIEILAKEIEVLNAAATPPFQIDDENISENVRLTNRVIDLRRPAMQRNLRLRYQVAMGVRRYLDAQGFID
IETPMLTRSTPEGARDYLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDLETSFL
NEDEIMDITEGMAKQVFKDALNVDLGDFPRMPYAEAMFYYGSDKPDMRINLKFTELTDLMKTEEFKVFRGAADMKGGRVV
ALRVPNGAKFSRKEIDEYTKFVGIYGAKGLAYIKVNDVGNLSNGEDSGLQSPIVKFLSENALKEIIERTGAQNGDIIFFG
ADKTKVVNEAIGALRIKVGLEHGKDNGYFTDEWKPLWVVDFPMFEYDEEADRYVAVHHPFTAPKEGHEDLMVSDPANCLA
RAYDMVLNGWEIGGGSIRIHRADVQEKVFAALKISPEEQQEKFGFLLDNLKFGAPPHGGLAFGLDRLVTLMTGAESIRDV
IAFPKTQRAQCLLTNAPNSVDDKQLRELSLRLRQKAAETKEA

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=613, Percent_Identity=40.6199021207178, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI45439306, Length=268, Percent_Identity=28.7313432835821, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI194272210, Length=253, Percent_Identity=26.4822134387352, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI5031815, Length=253, Percent_Identity=26.4822134387352, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI4758762, Length=292, Percent_Identity=26.027397260274, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1788173, Length=598, Percent_Identity=56.0200668896321, Blast_Score=683, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=309, Percent_Identity=24.5954692556634, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789256, Length=254, Percent_Identity=25.9842519685039, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787161, Length=290, Percent_Identity=27.9310344827586, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI32566633, Length=614, Percent_Identity=35.5048859934853, Blast_Score=329, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI17551876, Length=269, Percent_Identity=28.996282527881, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71984122, Length=341, Percent_Identity=26.6862170087977, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994340, Length=296, Percent_Identity=22.2972972972973, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17535927, Length=296, Percent_Identity=22.2972972972973, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17535925, Length=296, Percent_Identity=22.2972972972973, Blast_Score=86, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6325153, Length=639, Percent_Identity=32.8638497652582, Blast_Score=288, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6321807, Length=241, Percent_Identity=27.8008298755187, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323011, Length=261, Percent_Identity=26.8199233716475, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320242, Length=259, Percent_Identity=23.9382239382239, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324256, Length=156, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24584738, Length=603, Percent_Identity=36.81592039801, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI17136276, Length=264, Percent_Identity=30.6818181818182, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24640849, Length=253, Percent_Identity=28.0632411067194, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640851, Length=253, Percent_Identity=28.0632411067194, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19921528, Length=232, Percent_Identity=29.7413793103448, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 68048; Mature: 68048

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPDTPEAFAAA
CCCCCCCCHHHHHCCCEEEEEHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHH
DSARNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVLNAAATPPFQIDDENISEN
HCCCCCEEEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCCEECCCCCCCC
VRLTNRVIDLRRPAMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARDYLVP
HHHHHHHHHHHCHHHHCCCEEEHHHHHHHHHHHCCCCEEEECCCCEECCCCCCCHHCCCC
SRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDLETSFL
CCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHC
NEDEIMDITEGMAKQVFKDALNVDLGDFPRMPYAEAMFYYGSDKPDMRINLKFTELTDLM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCCCCEEEEEEHHHHHHHH
KTEEFKVFRGAADMKGGRVVALRVPNGAKFSRKEIDEYTKFVGIYGAKGLAYIKVNDVGN
HHHHHHEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCEEEEEEECCCC
LSNGEDSGLQSPIVKFLSENALKEIIERTGAQNGDIIFFGADKTKVVNEAIGALRIKVGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHCEEEEEEEE
EHGKDNGYFTDEWKPLWVVDFPMFEYDEEADRYVAVHHPFTAPKEGHEDLMVSDPANCLA
ECCCCCCEECCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECHHHHHH
RAYDMVLNGWEIGGGSIRIHRADVQEKVFAALKISPEEQQEKFGFLLDNLKFGAPPHGGL
HHHHHHHCCEEECCCEEEEEECCHHHHHHHHEECCCHHHHHHHHHHHHCCCCCCCCCCCH
AFGLDRLVTLMTGAESIRDVIAFPKTQRAQCLLTNAPNSVDDKQLRELSLRLRQKAAETK
HHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
EA
CC
>Mature Secondary Structure
MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPDTPEAFAAA
CCCCCCCCHHHHHCCCEEEEEHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHH
DSARNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVLNAAATPPFQIDDENISEN
HCCCCCEEEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCCEECCCCCCCC
VRLTNRVIDLRRPAMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARDYLVP
HHHHHHHHHHHCHHHHCCCEEEHHHHHHHHHHHCCCCEEEECCCCEECCCCCCCHHCCCC
SRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDLETSFL
CCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHC
NEDEIMDITEGMAKQVFKDALNVDLGDFPRMPYAEAMFYYGSDKPDMRINLKFTELTDLM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCCCCEEEEEEHHHHHHHH
KTEEFKVFRGAADMKGGRVVALRVPNGAKFSRKEIDEYTKFVGIYGAKGLAYIKVNDVGN
HHHHHHEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCEEEEEEECCCC
LSNGEDSGLQSPIVKFLSENALKEIIERTGAQNGDIIFFGADKTKVVNEAIGALRIKVGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHCEEEEEEEE
EHGKDNGYFTDEWKPLWVVDFPMFEYDEEADRYVAVHHPFTAPKEGHEDLMVSDPANCLA
ECCCCCCEECCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECHHHHHH
RAYDMVLNGWEIGGGSIRIHRADVQEKVFAALKISPEEQQEKFGFLLDNLKFGAPPHGGL
HHHHHHHCCEEECCCEEEEEECCHHHHHHHHEECCCHHHHHHHHHHHHCCCCCCCCCCCH
AFGLDRLVTLMTGAESIRDVIAFPKTQRAQCLLTNAPNSVDDKQLRELSLRLRQKAAETK
HHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
EA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA