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The map label for this gene is porA [H]

Identifier: 161870296

GI number: 161870296

Start: 1350328

End: 1351491

Strand: Reverse

Name: porA [H]

Synonym: NMCC_1338

Alternate gene names: 161870296

Gene position: 1351491-1350328 (Counterclockwise)

Preceding gene: 161870299

Following gene: 161870294

Centisome position: 62.76

GC content: 52.75

Gene sequence:

>1164_bases
ATGCGAAAAAAACTTACCGCCCTCGTATTGTCCGCACTGCCGCTTGCGGCCGTTGCCAATGTCAGCCTATACGGCGAAAT
CAAAGCCGGCGTGGAAGGCAGGAACTACCAGCTGCAATTGACTGAAGCACAAGCCGCTAACGGTGGAGCGAGCGGTCAGG
TAAAAGTTACTAAGGCCAAAAGCCGCATCAGGACGAAAATCAGTGATTTCGGCTCGTTTATCGGCTTTAAGGGGAGTGAG
GATTTGGGCGAAGGGCTGAAGGCTGTTTGGCAGCTTGAGCAAGACGTATCCGTTGCCGGCGGCGGCGCGACCCAGTGGGG
CAACAGGGAATCCTTTATCGGCTTGGCAGGCGAATTCGGTACGCTGCGCGCCGGTCGCGTTGCGAATCAGTTTGACGATG
CCAGCCAAGCCATTGATCCTTGGGACAGCAACAATGATGTGGCTTCGCAATTGGGTATTTTCAAACGCCACGACGATATG
CCGGTTTCCGTACGCTACGACTCTCCGGACTTTTCCGGTTTCAGCGGCAGCGTCCAATTCGTTCCGGCTCAAAACAGCAA
GTCCGCCTATAAGCCGGCTTATGTGGATGAGAAGAAAATGGTTCATGCGGCTGTTGTCGGCAAGCCCGGATCGGATGTGT
ATTATGCCGGTCTGAATTACAAAAATGGCGGATTTGCCGGGAGCTATGCCTTTAAATATGCGAGACACGCCAATGTCGGA
CGTGATGCTTTTGAGTTGTTCTTGCTCGGCAGCACGAGTGATGAAGCCAAAGGTACCGATCCCTTGAAAAACCATCAGGT
ACACCGCCTGACGGGCGGCTATGAGGAAGGCGGCTTGAATCTCGCCTTGGCGGCTCAGTTGGATTTGTCTGAAAATGGCG
ACAAAGCCAAAACCAAAAACAGTACGACCGAAATTGCCGCGACTGCTTCCTACCGCTTCGGTAATGCAGTTCCACGCATC
AGCTATGCCCATGGTTTTGACTTGATCGAACGCGGTAAAAAAGGCGAAAATACCAGCTACGATCAAATCATCGCCGGCGT
TGATTATGATTTTTCCAAACGCACTTCCGCCATCGTGTCTGGCGCTTGGCTGAAACGCAATACCGGCATCGGCAACTACA
CTCAAATTAATGCCGCCTCCGTCGGTTTGCGCCACAAATTCTAA

Upstream 100 bases:

>100_bases
AAAAATGGTTTTTTGCGGGGGGGGGGGGTATAATTGAAGACGTATCGGGTGTTTGCCCGATGTTTTTAGGTTTTTATCAA
ATTTACAAAAGGAAGCAGAT

Downstream 100 bases:

>100_bases
ATATCGGGGCGGTGAAGCGGATAGCTTTGTTTTTGACGGCTTGCTTTCATTCTTTGATTGCAATCTGACTGCCAATCTGC
TTCAGCCCCAAACAAAAATC

Product: porin, class I outer membrane protein

Products: NA

Alternate protein names: PIA; Protein IA; Class 1 protein [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MRKKLTALVLSALPLAAVANVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKAKSRIRTKISDFGSFIGFKGSE
DLGEGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDM
PVSVRYDSPDFSGFSGSVQFVPAQNSKSAYKPAYVDEKKMVHAAVVGKPGSDVYYAGLNYKNGGFAGSYAFKYARHANVG
RDAFELFLLGSTSDEAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRI
SYAHGFDLIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF

Sequences:

>Translated_387_residues
MRKKLTALVLSALPLAAVANVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKAKSRIRTKISDFGSFIGFKGSE
DLGEGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDM
PVSVRYDSPDFSGFSGSVQFVPAQNSKSAYKPAYVDEKKMVHAAVVGKPGSDVYYAGLNYKNGGFAGSYAFKYARHANVG
RDAFELFLLGSTSDEAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRI
SYAHGFDLIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF
>Mature_387_residues
MRKKLTALVLSALPLAAVANVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKAKSRIRTKISDFGSFIGFKGSE
DLGEGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDM
PVSVRYDSPDFSGFSGSVQFVPAQNSKSAYKPAYVDEKKMVHAAVVGKPGSDVYYAGLNYKNGGFAGSYAFKYARHANVG
RDAFELFLLGSTSDEAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRI
SYAHGFDLIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF

Specific function: Serves as a slightly cation selective porin. Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity [H]

COG id: COG3203

COG function: function code M; Outer membrane protein (porin)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Gram-negative porin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013793
- InterPro:   IPR001702
- InterPro:   IPR002299 [H]

Pfam domain/function: PF00267 Porin_1 [H]

EC number: NA

Molecular weight: Translated: 41483; Mature: 41483

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00576 GRAM_NEG_PORIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKLTALVLSALPLAAVANVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKAK
CCHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEEHHH
SRIRTKISDFGSFIGFKGSEDLGEGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCEEEECCCCC
TLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPDFSGFSGSVQF
CCCCCCHHHHHCCHHHHCCCCCCCCHHHHHHCHHCCCCCCEEEEEECCCCCCCCCCEEEE
VPAQNSKSAYKPAYVDEKKMVHAAVVGKPGSDVYYAGLNYKNGGFAGSYAFKYARHANVG
EECCCCCCCCCCCCCCHHHEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCC
RDAFELFLLGSTSDEAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKN
CCEEEEEEECCCCCCCCCCCCHHCCEEEEECCCCCCCCEEEEEEEEEECCCCCCCCCCCC
STTEIAATASYRFGNAVPRISYAHGFDLIERGKKGENTSYDQIIAGVDYDFSKRTSAIVS
CCEEEEEEEEECCCCCCCCEEHHCCCHHHHCCCCCCCCCHHHEEECCCCCHHHHHHHHHC
GAWLKRNTGIGNYTQINAASVGLRHKF
CCEEECCCCCCCEEEEEHHCCCCCCCC
>Mature Secondary Structure
MRKKLTALVLSALPLAAVANVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKAK
CCHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEEHHH
SRIRTKISDFGSFIGFKGSEDLGEGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCEEEECCCCC
TLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPDFSGFSGSVQF
CCCCCCHHHHHCCHHHHCCCCCCCCHHHHHHCHHCCCCCCEEEEEECCCCCCCCCCEEEE
VPAQNSKSAYKPAYVDEKKMVHAAVVGKPGSDVYYAGLNYKNGGFAGSYAFKYARHANVG
EECCCCCCCCCCCCCCHHHEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCC
RDAFELFLLGSTSDEAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKN
CCEEEEEEECCCCCCCCCCCCHHCCEEEEECCCCCCCCEEEEEEEEEECCCCCCCCCCCC
STTEIAATASYRFGNAVPRISYAHGFDLIERGKKGENTSYDQIIAGVDYDFSKRTSAIVS
CCEEEEEEEEECCCCCCCCEEHHCCCHHHHCCCCCCCCCHHHEEECCCCCHHHHHHHHHC
GAWLKRNTGIGNYTQINAASVGLRHKF
CCEEECCCCCCCEEEEEHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]