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The map label for this gene is xseA [H]

Identifier: 161870233

GI number: 161870233

Start: 1275724

End: 1277133

Strand: Reverse

Name: xseA [H]

Synonym: NMCC_1274

Alternate gene names: 161870233

Gene position: 1277133-1275724 (Counterclockwise)

Preceding gene: 161870235

Following gene: 161870232

Centisome position: 59.31

GC content: 54.75

Gene sequence:

>1410_bases
ATGCCGCCTTGGGCTTCAAAACATATTCATATTTTTTACTATTTGATTGATTCGATGTCTGATTTTTTCCATTCTGACGT
GTTGTCCGTTTCCGAGTTGAACGCATTTGCCAAAAGTATTTTGGAAAACCACCTTGCCGGTCTGTGGATTGCGGGCGAAG
TATCCAACCTGACCCGTGCCGCCAGCGGACATTATTACTTCTCGCTCAAAGACAGCCGTGCGCAGGTGCGTTGCGCGATG
TTTAAGGGTGCGGCCATGCGCTTGGCGAAACCTTTGAAAGAAGGCGACCATATCGAGGTATCAGGGAAAATCAGCATTTA
CGAGGCACGGGGCGAATTTCAGATTACCGTGAACGAGGTGCGGCTCAAAGGTTTGGGGCAGCTTTACGAAGCCTATGAGC
GATTAAAAGCACAGTTGCAGGCGGAAGGCGCGTTTGCGGCGGAACGCAAAAAACCGTTGCCTCCCCGCCCGCAATGCATC
GGCATCGTAACCAGTCTGGCGGCAGCGGCATTGCGCGATGTCGTGACCACCTTAAACCGCCGCGCGCCCGAAATTCCCGT
TATCGTTTATCCAACGCCCGTTCAAGGCACAGGTAGTGAGTTGCAAATTGCCCAAGCGATTAAAACCGCTTCGCAACGCG
CCGAGTGTGACGTGCTGATTGTCTGTCGCGGCGGCGGCAGCATCGAAGACTTGTGGGCGTTTAATGAAGAGCCGGTCGTA
CGCGCCATCGAAGCCTGCTCAATTCCGGTCGTCAGCGGCGTAGGACACGAAACCGATTTCACGCTTGCCGATTTCGTCGC
CGACGTACGCGCACCGACACCGACCGGCGCCGCAGAATTGGTCAGCCCCAACCGCCAAGAATCGTTACACCGCCTCGCCC
AAGCGCAAGGCCATCTGAAAACCATTTTGGAACAACGCTATTTCGATGCCAGCCAAAAACTCGACTGGCTGGCGCGGCAA
ATCCGTCATCCGCGCCAAAAACTTGACGATCAGCGCACCTACATTCACAAACTGGTGCAAACCCTGTCCTACTCGATGAC
GCAAAACCTCCGCGCCCATACCGCCCGTTTTGAACGCCAAACCCAAACCCTGAAACATTGCCGTCCTGATGTTTCCGTTT
ACAAACACAACATCGACCGCTTTCAGACGGCCCTGTCGCACGCCTTCCACCAACTGCTTACCCACCGCCGCCAAAGCCTG
ACCGCCCAAGCAGCATTGCTCGAAGCCGTTTCGCCGCAGCACATTCTGGAGCGCGGCTTTTCCGTCGTCAAAAACACACG
CGGACAAGTCATCCGCAACGCCGATGTTTTGAAGCAGGGGCAGAAGCTGCACATTATCTTCGCCGACGGCGAAACCGACG
TGCGCGTAAGCAAAGAACAAGGGCAGCAGGATTTGTTCGATTGCATTTAA

Upstream 100 bases:

>100_bases
ATGAATATTTTTCCCATTCCCCGCTTAAAAAAGTCATACGGGCAAAGTCGGGCGGCAAGATGGCGCGTGTTATAATATTG
TTGACAATTTAGGCGGCTCT

Downstream 100 bases:

>100_bases
ACCCAATCGGAAAAACCGCTCCCCCTCCGCCGTCATTCCCGCGAAAGCGGGAATCCAGTCCCTTGACCTTAAGATAATCT
TTAATTCGTCATTCCTGAAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MPPWASKHIHIFYYLIDSMSDFFHSDVLSVSELNAFAKSILENHLAGLWIAGEVSNLTRAASGHYYFSLKDSRAQVRCAM
FKGAAMRLAKPLKEGDHIEVSGKISIYEARGEFQITVNEVRLKGLGQLYEAYERLKAQLQAEGAFAAERKKPLPPRPQCI
GIVTSLAAAALRDVVTTLNRRAPEIPVIVYPTPVQGTGSELQIAQAIKTASQRAECDVLIVCRGGGSIEDLWAFNEEPVV
RAIEACSIPVVSGVGHETDFTLADFVADVRAPTPTGAAELVSPNRQESLHRLAQAQGHLKTILEQRYFDASQKLDWLARQ
IRHPRQKLDDQRTYIHKLVQTLSYSMTQNLRAHTARFERQTQTLKHCRPDVSVYKHNIDRFQTALSHAFHQLLTHRRQSL
TAQAALLEAVSPQHILERGFSVVKNTRGQVIRNADVLKQGQKLHIIFADGETDVRVSKEQGQQDLFDCI

Sequences:

>Translated_469_residues
MPPWASKHIHIFYYLIDSMSDFFHSDVLSVSELNAFAKSILENHLAGLWIAGEVSNLTRAASGHYYFSLKDSRAQVRCAM
FKGAAMRLAKPLKEGDHIEVSGKISIYEARGEFQITVNEVRLKGLGQLYEAYERLKAQLQAEGAFAAERKKPLPPRPQCI
GIVTSLAAAALRDVVTTLNRRAPEIPVIVYPTPVQGTGSELQIAQAIKTASQRAECDVLIVCRGGGSIEDLWAFNEEPVV
RAIEACSIPVVSGVGHETDFTLADFVADVRAPTPTGAAELVSPNRQESLHRLAQAQGHLKTILEQRYFDASQKLDWLARQ
IRHPRQKLDDQRTYIHKLVQTLSYSMTQNLRAHTARFERQTQTLKHCRPDVSVYKHNIDRFQTALSHAFHQLLTHRRQSL
TAQAALLEAVSPQHILERGFSVVKNTRGQVIRNADVLKQGQKLHIIFADGETDVRVSKEQGQQDLFDCI
>Mature_468_residues
PPWASKHIHIFYYLIDSMSDFFHSDVLSVSELNAFAKSILENHLAGLWIAGEVSNLTRAASGHYYFSLKDSRAQVRCAMF
KGAAMRLAKPLKEGDHIEVSGKISIYEARGEFQITVNEVRLKGLGQLYEAYERLKAQLQAEGAFAAERKKPLPPRPQCIG
IVTSLAAAALRDVVTTLNRRAPEIPVIVYPTPVQGTGSELQIAQAIKTASQRAECDVLIVCRGGGSIEDLWAFNEEPVVR
AIEACSIPVVSGVGHETDFTLADFVADVRAPTPTGAAELVSPNRQESLHRLAQAQGHLKTILEQRYFDASQKLDWLARQI
RHPRQKLDDQRTYIHKLVQTLSYSMTQNLRAHTARFERQTQTLKHCRPDVSVYKHNIDRFQTALSHAFHQLLTHRRQSLT
AQAALLEAVSPQHILERGFSVVKNTRGQVIRNADVLKQGQKLHIIFADGETDVRVSKEQGQQDLFDCI

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=435, Percent_Identity=41.6091954022989, Blast_Score=338, Evalue=4e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 52512; Mature: 52380

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPWASKHIHIFYYLIDSMSDFFHSDVLSVSELNAFAKSILENHLAGLWIAGEVSNLTRA
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHH
ASGHYYFSLKDSRAQVRCAMFKGAAMRLAKPLKEGDHIEVSGKISIYEARGEFQITVNEV
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECEEEEEEECCCEEEEHHHH
RLKGLGQLYEAYERLKAQLQAEGAFAAERKKPLPPRPQCIGIVTSLAAAALRDVVTTLNR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RAPEIPVIVYPTPVQGTGSELQIAQAIKTASQRAECDVLIVCRGGGSIEDLWAFNEEPVV
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCHHH
RAIEACSIPVVSGVGHETDFTLADFVADVRAPTPTGAAELVSPNRQESLHRLAQAQGHLK
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHH
TILEQRYFDASQKLDWLARQIRHPRQKLDDQRTYIHKLVQTLSYSMTQNLRAHTARFERQ
HHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQTLKHCRPDVSVYKHNIDRFQTALSHAFHQLLTHRRQSLTAQAALLEAVSPQHILERGF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SVVKNTRGQVIRNADVLKQGQKLHIIFADGETDVRVSKEQGQQDLFDCI
HHHHCCCCHHEECHHHHHCCCEEEEEEECCCCCEEECHHCCHHHHHHCC
>Mature Secondary Structure 
PPWASKHIHIFYYLIDSMSDFFHSDVLSVSELNAFAKSILENHLAGLWIAGEVSNLTRA
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHH
ASGHYYFSLKDSRAQVRCAMFKGAAMRLAKPLKEGDHIEVSGKISIYEARGEFQITVNEV
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECEEEEEEECCCEEEEHHHH
RLKGLGQLYEAYERLKAQLQAEGAFAAERKKPLPPRPQCIGIVTSLAAAALRDVVTTLNR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RAPEIPVIVYPTPVQGTGSELQIAQAIKTASQRAECDVLIVCRGGGSIEDLWAFNEEPVV
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCHHH
RAIEACSIPVVSGVGHETDFTLADFVADVRAPTPTGAAELVSPNRQESLHRLAQAQGHLK
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHH
TILEQRYFDASQKLDWLARQIRHPRQKLDDQRTYIHKLVQTLSYSMTQNLRAHTARFERQ
HHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQTLKHCRPDVSVYKHNIDRFQTALSHAFHQLLTHRRQSLTAQAALLEAVSPQHILERGF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SVVKNTRGQVIRNADVLKQGQKLHIIFADGETDVRVSKEQGQQDLFDCI
HHHHCCCCHHEECHHHHHCCCEEEEEEECCCCCEEECHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA