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The map label for this gene is eno [H]

Identifier: 161870159

GI number: 161870159

Start: 1189767

End: 1191053

Strand: Direct

Name: eno [H]

Synonym: NMCC_1198

Alternate gene names: 161870159

Gene position: 1189767-1191053 (Clockwise)

Preceding gene: 161870158

Following gene: 161870160

Centisome position: 55.25

GC content: 54.62

Gene sequence:

>1287_bases
ATGAGCGCAATCGTTGATATTTTCGCCCGCGAAATTTTGGACTCACGCGGCAACCCCACAGTCGAGTGTGATGTATTGCT
CGAATCCGGCGTAATGGGACGCGCAGCCGTACCGAGCGGCGCGTCCACCGGTCAAAAAGAGGCTTTGGAACTTCGCGACG
GCGACAAATCCCGCTATTCCGGCAAGGGCGTATTGAAGGCGGTCGAACACGTCAACAACCAAATCGCCCAAGCCCTCATC
GGTATCGATGCCAACGAGCAATCTTATATCGACCAAATCATGATCGAATTGGACGGTACTGAAAACAAAGGCAATTTGGG
TGCGAATGCGACTTTGGCGGTTTCTATGGCGGTTGCACGCGCCGCTGCCGAAGACTCAGGCCTGCCGCTTTACCGCTACT
TGGGCGGCGCAGGCCCGATGTCCCTGCCCGTACCGATGATGAACGTCATCAACGGCGGCGAACACGCCAACAACAGCCTG
AACATCCAAGAGTTTATGATTATGCCCGTCGGCGCAAAATCTTTCCGCGAAGCATTGCGCTGCGGTGCGGAAATTTTCCA
CGCCTTGAAAAAACTGTGCGACAGCAAAGGCTTCCCAACCACAGTCGGCGACGAAGGCGGTTTCGCCCCCAACCTGAACA
GCCACAAAGAAGCCCTGCAACTGATGGTTGAAGCCACCGAAGCCGCCGGCTACAAAGCGGGCGAAGACGTATTATTCGCA
TTGGACTGCGCCTCCAGCGAGTTCTACAAAGACGGCAAATACCACTTGGAAGCCGAAGGCCGCTCCTACACCAACGCGGA
ATTTGCCGAATATCTGGAAAGTCTGGTCAACGAGTTCCCCATCATCTCCATCGAAGACGGCATGGATGAAAATGACTGGG
AAGGCTGGAAACTGCTGACCGAAAAACTGGGTGGCAAAGTCCAACTCGTTGGCGACGACCTCTTCGTTACCAACCCGAAA
ATCCTTGCCGAAGGCATTGAAAAAGGCGTGGCAAACGCACTATTGGTCAAAGTCAACCAAATCGGTACTTTGAGCGAGAC
CCTGAAAGCCGTCGACTTAGCCAAACGCAACCGCTACGCCAGCGTAATGAGCCACCGCTCCGGCGAAACCGAAGACAGCA
CCATTGCCGACTTGGCAGTCGCCACCAACTGTATGCAGATCAAAACCGGTTCTTTGAGCCGTTCCGACCGCATGGCAAAA
TACAACCAACTGCTGCGTATCGAGGAAGAATTGGCGGAAGCCGCCGACTACCCCGGCAAAGCCGCATTCTACCAACTGGG
CAAATAA

Upstream 100 bases:

>100_bases
GCCCTACTTTCAGCAGTTTTAAGTTGGCGGCTTTCCGGCAAAGATGCCGTCTGAAGCCCTCCCATTTTTTACCTCCCTTC
ACTTCACTTGGAGAACATTC

Downstream 100 bases:

>100_bases
GAAAAGGTTAAGGTATGAAGTGGGTAACTGTCGTTTTATCCTTCGCACTTGTCTGTTGCCAATACAGCCTCTGGTTCGGC
AAAGGCAGCATCGGACGCAA

Product: phosphopyruvate hydratase

Products: NA

Alternate protein names: 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKGVLKAVEHVNNQIAQALI
GIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSL
NIQEFMIMPVGAKSFREALRCGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFA
LDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLESLVNEFPIISIEDGMDENDWEGWKLLTEKLGGKVQLVGDDLFVTNPK
ILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAK
YNQLLRIEEELAEAADYPGKAAFYQLGK

Sequences:

>Translated_428_residues
MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKGVLKAVEHVNNQIAQALI
GIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSL
NIQEFMIMPVGAKSFREALRCGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFA
LDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLESLVNEFPIISIEDGMDENDWEGWKLLTEKLGGKVQLVGDDLFVTNPK
ILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAK
YNQLLRIEEELAEAADYPGKAAFYQLGK
>Mature_427_residues
SAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKGVLKAVEHVNNQIAQALIG
IDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLN
IQEFMIMPVGAKSFREALRCGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFAL
DCASSEFYKDGKYHLEAEGRSYTNAEFAEYLESLVNEFPIISIEDGMDENDWEGWKLLTEKLGGKVQLVGDDLFVTNPKI
LAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKY
NQLLRIEEELAEAADYPGKAAFYQLGK

Specific function: Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis [H]

COG id: COG0148

COG function: function code G; Enolase

Gene ontology:

Cell location: Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the bacterial ce

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enolase family [H]

Homologues:

Organism=Homo sapiens, GI5803011, Length=429, Percent_Identity=53.6130536130536, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI4503571, Length=430, Percent_Identity=52.5581395348837, Blast_Score=434, Evalue=1e-122,
Organism=Homo sapiens, GI301897477, Length=430, Percent_Identity=53.0232558139535, Blast_Score=434, Evalue=1e-121,
Organism=Homo sapiens, GI301897469, Length=430, Percent_Identity=53.0232558139535, Blast_Score=434, Evalue=1e-121,
Organism=Homo sapiens, GI301897479, Length=428, Percent_Identity=47.8971962616822, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI169201331, Length=339, Percent_Identity=27.4336283185841, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI169201757, Length=339, Percent_Identity=27.4336283185841, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI239744207, Length=339, Percent_Identity=27.4336283185841, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310129182, Length=123, Percent_Identity=32.520325203252, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI310110045, Length=123, Percent_Identity=32.520325203252, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI310120572, Length=123, Percent_Identity=32.520325203252, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789141, Length=425, Percent_Identity=63.7647058823529, Blast_Score=546, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI71995829, Length=431, Percent_Identity=53.8283062645012, Blast_Score=432, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17536383, Length=431, Percent_Identity=53.8283062645012, Blast_Score=432, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI32563855, Length=191, Percent_Identity=47.1204188481675, Blast_Score=177, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6321693, Length=433, Percent_Identity=51.0392609699769, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6323985, Length=432, Percent_Identity=49.3055555555556, Blast_Score=391, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6324974, Length=432, Percent_Identity=49.3055555555556, Blast_Score=391, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6324969, Length=432, Percent_Identity=49.3055555555556, Blast_Score=391, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6321968, Length=433, Percent_Identity=51.0392609699769, Blast_Score=384, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24580918, Length=428, Percent_Identity=52.3364485981308, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24580916, Length=428, Percent_Identity=52.3364485981308, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24580920, Length=428, Percent_Identity=52.3364485981308, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24580914, Length=428, Percent_Identity=52.3364485981308, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI281360527, Length=428, Percent_Identity=52.3364485981308, Blast_Score=406, Evalue=1e-113,
Organism=Drosophila melanogaster, GI17137654, Length=428, Percent_Identity=52.3364485981308, Blast_Score=406, Evalue=1e-113,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000941
- InterPro:   IPR020810
- InterPro:   IPR020809
- InterPro:   IPR020811 [H]

Pfam domain/function: PF00113 Enolase_C; PF03952 Enolase_N [H]

EC number: =4.2.1.11 [H]

Molecular weight: Translated: 46107; Mature: 45975

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00164 ENOLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYS
CHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
GKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVAR
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHH
AAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALR
HHHCCCCCCHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
CGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
LDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLESLVNEFPIISIEDGMDENDWEGWKLLT
EECCCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHH
EKLGGKVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYA
HHHCCEEEEEECCEEECCHHHHHHHHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHH
SVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAADYPGK
HHHHHCCCCCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AAFYQLGK
HHHHCCCC
>Mature Secondary Structure 
SAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYS
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
GKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVAR
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHH
AAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALR
HHHCCCCCCHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
CGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
LDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLESLVNEFPIISIEDGMDENDWEGWKLLT
EECCCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHH
EKLGGKVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYA
HHHCCEEEEEECCEEECCHHHHHHHHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHH
SVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAADYPGK
HHHHHCCCCCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AAFYQLGK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA