Click here to switch to the map view.

The map label for this gene is mfd [H]

Identifier: 161870155

GI number: 161870155

Start: 1183754

End: 1187869

Strand: Direct

Name: mfd [H]

Synonym: NMCC_1194

Alternate gene names: 161870155

Gene position: 1183754-1187869 (Clockwise)

Preceding gene: 161870151

Following gene: 161870156

Centisome position: 54.97

GC content: 56.8

Gene sequence:

>4116_bases
ATGACCTACCCCATCCCCAAACCCCGTGAAAAATCCCGTTGGTCCAATCTTTCGCAAGGCTCGCTGCCCTTGGCTTTGGC
GCGTTATCTGCCGCATAAGCGGCTCAAGGTCGTGCTGACCCAAGATGCGGAACAGGCGCTACGCCTTCAGACGGCATGGC
GGTTTTTCCGTCCGCACGACACGGCGGTGTTCCTGCCGGACTGGGAAACGCTGCCTTACGAGCGTTTTTCGCCGCATCAG
GATTTGGTGTCGGAACGGCTGTCGGCGTTGTGGCAGATTAAGAGCGGCGCGGCGGACGTGTTGTTCGTGCCGGTTGCCAC
GGCGATGCAGAAGCTGCCGCCCGTGCCGTTTCTGGCAGGGCGCACGTTTTGGCTGAAAACAGGGCAGACTTTGGATATAG
GCCGTCTGAAAACCGATTTGGTAGATGCGGGCTACAACCATGTTTCCCATGTTGTTGCGGCGGGCGAGTTTGCCGTGCGC
GGCGGCATTGTCGATTTGTTCCCCATGGGCAGCGAAATGCCCTACCGCATCGATTTGTTTGACGATGAAATCGACAGCAT
CAAAACCTTTGATACGGACACGCAGCGCACCATCTCCCCCGTTTCCGAAATCCGCCTGCTGTCGGCGCACGAATTCCCCA
CCGACAGCGAGGCGCAAAAAATCTTCCGCAGCCGCTTCCGCGAGGAAGTCGATGGTAATCCGAACGATGCGGCTGTATAC
AAAGCAGTAAGCAACGGCCACTTCGGTGCGGGCGTGGAATATTACCTGCCGCTGTTTTTTGAAAACGAGCTGGAAACGCT
GTTTGACTATATCGGCGAAGACGCGCTGTTTGTCTCTTTGGGCGATGTTCACGCCGAGGCAAACCGCTTTTGGAGCGACG
TCAAATCGCGTTACGCCATGGCGCAGGGCGACGAAACCTATCCGCCTTTGCTTCCACAGCATTTGTATCTCTCCTCAGAT
GTTTTTGCAGGCCGTCTGAAAAATTATGGTCAGGTATTGCCGGATATTTTTGGTGTTGAACATACGTTGCCAAACGTGGC
CGTCAACCGCCAAGCGGATGAACCGTTGCAGGCATTGAAAGATTTTCAGACGGCCTTTAAAGGACGGATTTTGTTGTGCG
CCGAAAGTTTGGGACGACGCGAAACCATGCTCGGTTTCTTGCAGCAAAACGGTTTGAAAGCCAAACCCGTGTCCGACTGG
CAGGGCTTTTTATCGGCACACGAGCCGCTGATGATTACAGTGGCGCCGTTGGCATACGGGTTCAAACTGGGCGGACTGCA
ATCGCCGAACCAACAGCAAACTACTTCCGCCTCCGAGGGAGAAGGCGATGCGGTTACCGACCAAACCGAATTTTCCGCAG
CCGCAACAAACCCTCTCCCTAGCCCTCTCCCACAGGAGAGGGAACAAAGTGCAGCCGCCGTTTCAACCGAAAGCAGCCTG
CCCCCCGGTAAAAGTAATCTGCACGGGCAAATCCAACAGCAACCTGCCCCCTCCCCCGTGGGGGAGGGTTGGGGAGAGGG
CAAAGCAGTTGCCGCTCAAACCGAATTTCCCGCATCCGCAACAAACCCTCTCCCTAACCCTCTCCCGCAGGAGAGGGAAC
AAAGTGCAGCCGTCGTTTCAGACAGTCTGAAAGCAGCCGCCGTTTCAACCGAAAGCAGCCTGCCCCCCGGTAAAAGTAAT
CTGCACGGGCAAATCCAACAGCAACCTGCCCCCTCCCCCGTGGGGGAGGGTTGGGGAGAGGGCAAAGCAGTTGCCGCTCA
AACCGAATTTTCCGCATCCGCAACAAACCCTCTCCCTAGCCCTCTCCCTCAGGAGAGGGAACAAAGTGCAGCCGTCGTTT
CAGACAGTCTGAAAGCAGCCGCCGTTTCAACCGAAAGCAGCCTGCCCCCCGGTAAAAGTAATCTGCACGGGCAAATCCAA
CAGCAACCTGCCCCCTCCCCCGTGGGGGAGGGTTGGGGAGAGGGCAAAGCAGTTGCCGCTCAAAGTGCCATCGCCGTCAT
CACCGAATCCGATCTCTACCAATACGTCGCCCGTTCGCGCGTCCACAACCGCCGCAAGAAACACGCCGCCGTTTCAGACG
GTCTGTTGCGCGACCTTGCCGAAATCAACATCGGCGACCCCGTCGTTCACGAAGAACACGGCATCGGGCGGTATATGGGC
TTGGTAACGATGGACTTGGGCGGCGAAACCAACGAAATGATGTTGCTCGAATACGCAGGAGAAGCGCAGCTTTATGTGCC
TGTTTCACAACTGCATTTAATCAGCCGCTACTCCGGTCAGGCGCATGAAAACATTGCCCTGCACAAGCTCGGCAGTGGCG
CGTGGAACAAGGCGAAGCGCAAAGCCGCCGAAAAGGCGCGCGATACCGCCGCCGAGTTGCTTAACCTTTACGCCCGACGC
GCTGCCCAATCGGGACACAAGTTTGAAATCAACGAGTTGGATTATCAGGCGTTTGCTGACGGCTTCGGCTACGAGGAAAC
CGAAGACCAGGCCGCCGCCATCGCCGCCGTGATTAAAGATTTGACGCAAGCGAAGCCGATGGATCGCCTTGTGTGCGGCG
ATGTCGGCTTCGGCAAAACCGAAGTTGCCCTGCGCGCCGCGTTTGTGGCGGTGATGGGCGGCAAACAGGTCGCCGTACTC
GCCCCGACCACGCTTCTGGTCGAGCAGCACGCGCAAAACTTTGCCGACCGTTTCGCCGATTTCCCTGTGAAAGTCGCCAG
CCTTTCGCGTTTCAACAACAGCAAAGCCACTAAAGCCGCGCTGGAAGGCATGGCGGACGGCACGGTCGACATCGTTATCG
GCACGCACAAACTGGTGCAGGACGACATCAAATTCAAAAACTTAGGTTTAGTGATTATCGACGAAGAACACCGCTTCGGT
GTGCGCCAAAAAGAGCAGCTCAAACGCCTGCGTGCCAATGTCGACATCCTCACCATGACCGCCACGCCGATTCCGCGTAC
TTTAAGTATGGCGTTGGAAGGACTGCGCGACTTCTCGCTGATTACCACCGCGCCCAGCCGCCGCCTCGCCGTCAAAACCT
TTGTCAAACCCTTTAGCGAAGGCAGCGTGCGCGAAGCCGTGTTGCGCGAACTCAAACGCGGAGGACAGGTATTTTTCCTG
CACAATGAAGTAGATACGATTGAAAATATGCGCGAGCGGCTGGAAACCCTGCTGCCCGAAGCCCGCATCGGCGTGGCGCA
CGGACAACTGCGCGAGCGCGAGCTGGAACAAGTCATGCGCGACTTTTTACAGCAACGATTCAACGTGTTGCTCTGTTCCA
CCATCATCGAAACCGGTATCGACATTCCCAACGCCAACACCATCATCATCAACCGCGCCGACAAATTCGGACTGGCGCAA
CTGCACCAGCTTCGCGGGCGCGTCGGACGCAGCCACCACCAAGCCTACGCCTACCTGCTCACGCCCGAATACATCACCAA
AGACGCAGAAAAACGCCTCGACGCCATCGCGGCAGCAGACGAACTCGGCGCAGGTTTCACCCTCGCCATGCAGGATTTGG
AAATCCGCGGCGCAGGCGAAATCCTCGGCGAAGGGCAGTCCGGCGAAATGATACAGGTCGGCTTCACGCTCTACACCGAA
ATGCTCAAACAAGCCGTGCGCGATCTCAAAAAAGGCCGCCAACCCGACCTCGACGCGCCGCTGGGCATCACCACCGAAAT
CAAACTGCACAGCCCCGCCCTACTGCCCGAAAGCTACTGCCCCGACATCCACGAGCGTCTCGTCCTCTACAAACGCCTCG
CCGTCTGCGAAACCGTGCAGCAAATCAACGCCATACACGAAGAACTCGTCGACCGCTTCGGCCTGCCCGAACAACCCGTC
AAAACCCTTATCGAAAGCCACCACCTGCGGCTTATGGCAAAAGAATTGGGTATCGATGCCATTGATGCGGCCGGCGAAGC
GGTAACGGTAACCTTCGGTAAAAACAATAATGTCGATCCAACCGAAATCATCCTGCTGATTCAGAACGACAAAAAATACC
GCCTTGCCGGCGCCGATAAGCTGCGGTTTACCGCAGAGATGGAAAATATCGAGGTCAGAATCAACACCGTAAAAAACGTT
TTAAAAACCTTGCAAAACAGATGCCTGCCCAAATAA

Upstream 100 bases:

>100_bases
AAAGTGCGCCGGGCAACAATCCGCCGACCTTTCAGACAGCATCGCGCCCCCTCCCGTGCTAAAATGACCGTTTGCATCAC
TGTCCGCCGATTGCCGCACT

Downstream 100 bases:

>100_bases
AGCCGACACCGCAATGCCGTCTGAAACACCGTTTTCCTTGTCCGAAAGCCGCCATTATGAATTTGAAGGAAACTCCACTA
TAATACGGCATTCAGATTTC

Product: transcription-repair coupling factor

Products: NA

Alternate protein names: TRCF; ATP-dependent helicase mfd [H]

Number of amino acids: Translated: 1371; Mature: 1370

Protein sequence:

>1371_residues
MTYPIPKPREKSRWSNLSQGSLPLALARYLPHKRLKVVLTQDAEQALRLQTAWRFFRPHDTAVFLPDWETLPYERFSPHQ
DLVSERLSALWQIKSGAADVLFVPVATAMQKLPPVPFLAGRTFWLKTGQTLDIGRLKTDLVDAGYNHVSHVVAAGEFAVR
GGIVDLFPMGSEMPYRIDLFDDEIDSIKTFDTDTQRTISPVSEIRLLSAHEFPTDSEAQKIFRSRFREEVDGNPNDAAVY
KAVSNGHFGAGVEYYLPLFFENELETLFDYIGEDALFVSLGDVHAEANRFWSDVKSRYAMAQGDETYPPLLPQHLYLSSD
VFAGRLKNYGQVLPDIFGVEHTLPNVAVNRQADEPLQALKDFQTAFKGRILLCAESLGRRETMLGFLQQNGLKAKPVSDW
QGFLSAHEPLMITVAPLAYGFKLGGLQSPNQQQTTSASEGEGDAVTDQTEFSAAATNPLPSPLPQEREQSAAAVSTESSL
PPGKSNLHGQIQQQPAPSPVGEGWGEGKAVAAQTEFPASATNPLPNPLPQEREQSAAVVSDSLKAAAVSTESSLPPGKSN
LHGQIQQQPAPSPVGEGWGEGKAVAAQTEFSASATNPLPSPLPQEREQSAAVVSDSLKAAAVSTESSLPPGKSNLHGQIQ
QQPAPSPVGEGWGEGKAVAAQSAIAVITESDLYQYVARSRVHNRRKKHAAVSDGLLRDLAEINIGDPVVHEEHGIGRYMG
LVTMDLGGETNEMMLLEYAGEAQLYVPVSQLHLISRYSGQAHENIALHKLGSGAWNKAKRKAAEKARDTAAELLNLYARR
AAQSGHKFEINELDYQAFADGFGYEETEDQAAAIAAVIKDLTQAKPMDRLVCGDVGFGKTEVALRAAFVAVMGGKQVAVL
APTTLLVEQHAQNFADRFADFPVKVASLSRFNNSKATKAALEGMADGTVDIVIGTHKLVQDDIKFKNLGLVIIDEEHRFG
VRQKEQLKRLRANVDILTMTATPIPRTLSMALEGLRDFSLITTAPSRRLAVKTFVKPFSEGSVREAVLRELKRGGQVFFL
HNEVDTIENMRERLETLLPEARIGVAHGQLRERELEQVMRDFLQQRFNVLLCSTIIETGIDIPNANTIIINRADKFGLAQ
LHQLRGRVGRSHHQAYAYLLTPEYITKDAEKRLDAIAAADELGAGFTLAMQDLEIRGAGEILGEGQSGEMIQVGFTLYTE
MLKQAVRDLKKGRQPDLDAPLGITTEIKLHSPALLPESYCPDIHERLVLYKRLAVCETVQQINAIHEELVDRFGLPEQPV
KTLIESHHLRLMAKELGIDAIDAAGEAVTVTFGKNNNVDPTEIILLIQNDKKYRLAGADKLRFTAEMENIEVRINTVKNV
LKTLQNRCLPK

Sequences:

>Translated_1371_residues
MTYPIPKPREKSRWSNLSQGSLPLALARYLPHKRLKVVLTQDAEQALRLQTAWRFFRPHDTAVFLPDWETLPYERFSPHQ
DLVSERLSALWQIKSGAADVLFVPVATAMQKLPPVPFLAGRTFWLKTGQTLDIGRLKTDLVDAGYNHVSHVVAAGEFAVR
GGIVDLFPMGSEMPYRIDLFDDEIDSIKTFDTDTQRTISPVSEIRLLSAHEFPTDSEAQKIFRSRFREEVDGNPNDAAVY
KAVSNGHFGAGVEYYLPLFFENELETLFDYIGEDALFVSLGDVHAEANRFWSDVKSRYAMAQGDETYPPLLPQHLYLSSD
VFAGRLKNYGQVLPDIFGVEHTLPNVAVNRQADEPLQALKDFQTAFKGRILLCAESLGRRETMLGFLQQNGLKAKPVSDW
QGFLSAHEPLMITVAPLAYGFKLGGLQSPNQQQTTSASEGEGDAVTDQTEFSAAATNPLPSPLPQEREQSAAAVSTESSL
PPGKSNLHGQIQQQPAPSPVGEGWGEGKAVAAQTEFPASATNPLPNPLPQEREQSAAVVSDSLKAAAVSTESSLPPGKSN
LHGQIQQQPAPSPVGEGWGEGKAVAAQTEFSASATNPLPSPLPQEREQSAAVVSDSLKAAAVSTESSLPPGKSNLHGQIQ
QQPAPSPVGEGWGEGKAVAAQSAIAVITESDLYQYVARSRVHNRRKKHAAVSDGLLRDLAEINIGDPVVHEEHGIGRYMG
LVTMDLGGETNEMMLLEYAGEAQLYVPVSQLHLISRYSGQAHENIALHKLGSGAWNKAKRKAAEKARDTAAELLNLYARR
AAQSGHKFEINELDYQAFADGFGYEETEDQAAAIAAVIKDLTQAKPMDRLVCGDVGFGKTEVALRAAFVAVMGGKQVAVL
APTTLLVEQHAQNFADRFADFPVKVASLSRFNNSKATKAALEGMADGTVDIVIGTHKLVQDDIKFKNLGLVIIDEEHRFG
VRQKEQLKRLRANVDILTMTATPIPRTLSMALEGLRDFSLITTAPSRRLAVKTFVKPFSEGSVREAVLRELKRGGQVFFL
HNEVDTIENMRERLETLLPEARIGVAHGQLRERELEQVMRDFLQQRFNVLLCSTIIETGIDIPNANTIIINRADKFGLAQ
LHQLRGRVGRSHHQAYAYLLTPEYITKDAEKRLDAIAAADELGAGFTLAMQDLEIRGAGEILGEGQSGEMIQVGFTLYTE
MLKQAVRDLKKGRQPDLDAPLGITTEIKLHSPALLPESYCPDIHERLVLYKRLAVCETVQQINAIHEELVDRFGLPEQPV
KTLIESHHLRLMAKELGIDAIDAAGEAVTVTFGKNNNVDPTEIILLIQNDKKYRLAGADKLRFTAEMENIEVRINTVKNV
LKTLQNRCLPK
>Mature_1370_residues
TYPIPKPREKSRWSNLSQGSLPLALARYLPHKRLKVVLTQDAEQALRLQTAWRFFRPHDTAVFLPDWETLPYERFSPHQD
LVSERLSALWQIKSGAADVLFVPVATAMQKLPPVPFLAGRTFWLKTGQTLDIGRLKTDLVDAGYNHVSHVVAAGEFAVRG
GIVDLFPMGSEMPYRIDLFDDEIDSIKTFDTDTQRTISPVSEIRLLSAHEFPTDSEAQKIFRSRFREEVDGNPNDAAVYK
AVSNGHFGAGVEYYLPLFFENELETLFDYIGEDALFVSLGDVHAEANRFWSDVKSRYAMAQGDETYPPLLPQHLYLSSDV
FAGRLKNYGQVLPDIFGVEHTLPNVAVNRQADEPLQALKDFQTAFKGRILLCAESLGRRETMLGFLQQNGLKAKPVSDWQ
GFLSAHEPLMITVAPLAYGFKLGGLQSPNQQQTTSASEGEGDAVTDQTEFSAAATNPLPSPLPQEREQSAAAVSTESSLP
PGKSNLHGQIQQQPAPSPVGEGWGEGKAVAAQTEFPASATNPLPNPLPQEREQSAAVVSDSLKAAAVSTESSLPPGKSNL
HGQIQQQPAPSPVGEGWGEGKAVAAQTEFSASATNPLPSPLPQEREQSAAVVSDSLKAAAVSTESSLPPGKSNLHGQIQQ
QPAPSPVGEGWGEGKAVAAQSAIAVITESDLYQYVARSRVHNRRKKHAAVSDGLLRDLAEINIGDPVVHEEHGIGRYMGL
VTMDLGGETNEMMLLEYAGEAQLYVPVSQLHLISRYSGQAHENIALHKLGSGAWNKAKRKAAEKARDTAAELLNLYARRA
AQSGHKFEINELDYQAFADGFGYEETEDQAAAIAAVIKDLTQAKPMDRLVCGDVGFGKTEVALRAAFVAVMGGKQVAVLA
PTTLLVEQHAQNFADRFADFPVKVASLSRFNNSKATKAALEGMADGTVDIVIGTHKLVQDDIKFKNLGLVIIDEEHRFGV
RQKEQLKRLRANVDILTMTATPIPRTLSMALEGLRDFSLITTAPSRRLAVKTFVKPFSEGSVREAVLRELKRGGQVFFLH
NEVDTIENMRERLETLLPEARIGVAHGQLRERELEQVMRDFLQQRFNVLLCSTIIETGIDIPNANTIIINRADKFGLAQL
HQLRGRVGRSHHQAYAYLLTPEYITKDAEKRLDAIAAADELGAGFTLAMQDLEIRGAGEILGEGQSGEMIQVGFTLYTEM
LKQAVRDLKKGRQPDLDAPLGITTEIKLHSPALLPESYCPDIHERLVLYKRLAVCETVQQINAIHEELVDRFGLPEQPVK
TLIESHHLRLMAKELGIDAIDAAGEAVTVTFGKNNNVDPTEIILLIQNDKKYRLAGADKLRFTAEMENIEVRINTVKNVL
KTLQNRCLPK

Specific function: Necessary for strand-specific repair. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognized by TRCF which releases RNAP and the truncated transcript; the TCRF may replace RNAP at the

COG id: COG1197

COG function: function code LK; Transcription-repair coupling factor (superfamily II helicase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787357, Length=723, Percent_Identity=55.8782849239281, Blast_Score=811, Evalue=0.0,
Organism=Escherichia coli, GI2367254, Length=412, Percent_Identity=39.3203883495146, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI1790370, Length=206, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003711
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR004576
- InterPro:   IPR005118 [H]

Pfam domain/function: PF02559 CarD_TRCF; PF00270 DEAD; PF00271 Helicase_C; PF03461 TRCF [H]

EC number: NA

Molecular weight: Translated: 150663; Mature: 150531

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYPIPKPREKSRWSNLSQGSLPLALARYLPHKRLKVVLTQDAEQALRLQTAWRFFRPHD
CCCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCC
TAVFLPDWETLPYERFSPHQDLVSERLSALWQIKSGAADVLFVPVATAMQKLPPVPFLAG
CEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCEECC
RTFWLKTGQTLDIGRLKTDLVDAGYNHVSHVVAAGEFAVRGGIVDLFPMGSEMPYRIDLF
CEEEEECCCEEEHHHHHHHHHHCCHHHHHHHHHHCCHHHCCCCEEEEECCCCCCEEEEEC
DDEIDSIKTFDTDTQRTISPVSEIRLLSAHEFPTDSEAQKIFRSRFREEVDGNPNDAAVY
CCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHEE
KAVSNGHFGAGVEYYLPLFFENELETLFDYIGEDALFVSLGDVHAEANRFWSDVKSRYAM
EEECCCCCCCCHHHEEHHEEHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHH
AQGDETYPPLLPQHLYLSSDVFAGRLKNYGQVLPDIFGVEHTLPNVAVNRQADEPLQALK
HCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHH
DFQTAFKGRILLCAESLGRRETMLGFLQQNGLKAKPVSDWQGFLSAHEPLMITVAPLAYG
HHHHHHCCEEEEEEHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEHHHHH
FKLGGLQSPNQQQTTSASEGEGDAVTDQTEFSAAATNPLPSPLPQEREQSAAAVSTESSL
HEECCCCCCCCHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
PPGKSNLHGQIQQQPAPSPVGEGWGEGKAVAAQTEFPASATNPLPNPLPQEREQSAAVVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
DSLKAAAVSTESSLPPGKSNLHGQIQQQPAPSPVGEGWGEGKAVAAQTEFSASATNPLPS
HHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
PLPQEREQSAAVVSDSLKAAAVSTESSLPPGKSNLHGQIQQQPAPSPVGEGWGEGKAVAA
CCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
QSAIAVITESDLYQYVARSRVHNRRKKHAAVSDGLLRDLAEINIGDPVVHEEHGIGRYMG
HCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LVTMDLGGETNEMMLLEYAGEAQLYVPVSQLHLISRYSGQAHENIALHKLGSGAWNKAKR
EEEEECCCCCCCEEEEEECCCEEEEEEHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
KAAEKARDTAAELLNLYARRAAQSGHKFEINELDYQAFADGFGYEETEDQAAAIAAVIKD
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCCHHHHHCCCCCCCCHHHHHHHHHHHHH
LTQAKPMDRLVCGDVGFGKTEVALRAAFVAVMGGKQVAVLAPTTLLVEQHAQNFADRFAD
HHHCCCCHHHEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHC
FPVKVASLSRFNNSKATKAALEGMADGTVDIVIGTHKLVQDDIKFKNLGLVIIDEEHRFG
CCCHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHCCCEECCCEEEEECCCCCC
VRQKEQLKRLRANVDILTMTATPIPRTLSMALEGLRDFSLITTAPSRRLAVKTFVKPFSE
CCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCC
GSVREAVLRELKRGGQVFFLHNEVDTIENMRERLETLLPEARIGVAHGQLRERELEQVMR
CHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCHHHEECHHHHHHHHHHHHHHH
DFLQQRFNVLLCSTIIETGIDIPNANTIIINRADKFGLAQLHQLRGRVGRSHHQAYAYLL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEE
TPEYITKDAEKRLDAIAAADELGAGFTLAMQDLEIRGAGEILGEGQSGEMIQVGFTLYTE
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEEECCCHHHHCCCCCCCEEEEHHHHHHH
MLKQAVRDLKKGRQPDLDAPLGITTEIKLHSPALLPESYCPDIHERLVLYKRLAVCETVQ
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHCCCCHHHHHHHHHHHHHHHHHH
QINAIHEELVDRFGLPEQPVKTLIESHHLRLMAKELGIDAIDAAGEAVTVTFGKNNNVDP
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCH
TEIILLIQNDKKYRLAGADKLRFTAEMENIEVRINTVKNVLKTLQNRCLPK
HHEEEEEECCCEEEECCCCCEEEEEEECCEEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TYPIPKPREKSRWSNLSQGSLPLALARYLPHKRLKVVLTQDAEQALRLQTAWRFFRPHD
CCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCC
TAVFLPDWETLPYERFSPHQDLVSERLSALWQIKSGAADVLFVPVATAMQKLPPVPFLAG
CEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCEECC
RTFWLKTGQTLDIGRLKTDLVDAGYNHVSHVVAAGEFAVRGGIVDLFPMGSEMPYRIDLF
CEEEEECCCEEEHHHHHHHHHHCCHHHHHHHHHHCCHHHCCCCEEEEECCCCCCEEEEEC
DDEIDSIKTFDTDTQRTISPVSEIRLLSAHEFPTDSEAQKIFRSRFREEVDGNPNDAAVY
CCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHEE
KAVSNGHFGAGVEYYLPLFFENELETLFDYIGEDALFVSLGDVHAEANRFWSDVKSRYAM
EEECCCCCCCCHHHEEHHEEHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHH
AQGDETYPPLLPQHLYLSSDVFAGRLKNYGQVLPDIFGVEHTLPNVAVNRQADEPLQALK
HCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHH
DFQTAFKGRILLCAESLGRRETMLGFLQQNGLKAKPVSDWQGFLSAHEPLMITVAPLAYG
HHHHHHCCEEEEEEHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEHHHHH
FKLGGLQSPNQQQTTSASEGEGDAVTDQTEFSAAATNPLPSPLPQEREQSAAAVSTESSL
HEECCCCCCCCHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
PPGKSNLHGQIQQQPAPSPVGEGWGEGKAVAAQTEFPASATNPLPNPLPQEREQSAAVVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
DSLKAAAVSTESSLPPGKSNLHGQIQQQPAPSPVGEGWGEGKAVAAQTEFSASATNPLPS
HHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
PLPQEREQSAAVVSDSLKAAAVSTESSLPPGKSNLHGQIQQQPAPSPVGEGWGEGKAVAA
CCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
QSAIAVITESDLYQYVARSRVHNRRKKHAAVSDGLLRDLAEINIGDPVVHEEHGIGRYMG
HCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LVTMDLGGETNEMMLLEYAGEAQLYVPVSQLHLISRYSGQAHENIALHKLGSGAWNKAKR
EEEEECCCCCCCEEEEEECCCEEEEEEHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHH
KAAEKARDTAAELLNLYARRAAQSGHKFEINELDYQAFADGFGYEETEDQAAAIAAVIKD
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCCHHHHHCCCCCCCCHHHHHHHHHHHHH
LTQAKPMDRLVCGDVGFGKTEVALRAAFVAVMGGKQVAVLAPTTLLVEQHAQNFADRFAD
HHHCCCCHHHEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHC
FPVKVASLSRFNNSKATKAALEGMADGTVDIVIGTHKLVQDDIKFKNLGLVIIDEEHRFG
CCCHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCHHHHHHCCCEECCCEEEEECCCCCC
VRQKEQLKRLRANVDILTMTATPIPRTLSMALEGLRDFSLITTAPSRRLAVKTFVKPFSE
CCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCC
GSVREAVLRELKRGGQVFFLHNEVDTIENMRERLETLLPEARIGVAHGQLRERELEQVMR
CHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCHHHEECHHHHHHHHHHHHHHH
DFLQQRFNVLLCSTIIETGIDIPNANTIIINRADKFGLAQLHQLRGRVGRSHHQAYAYLL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEE
TPEYITKDAEKRLDAIAAADELGAGFTLAMQDLEIRGAGEILGEGQSGEMIQVGFTLYTE
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEEECCCHHHHCCCCCCCEEEEHHHHHHH
MLKQAVRDLKKGRQPDLDAPLGITTEIKLHSPALLPESYCPDIHERLVLYKRLAVCETVQ
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHCCCCHHHHHHHHHHHHHHHHHH
QINAIHEELVDRFGLPEQPVKTLIESHHLRLMAKELGIDAIDAAGEAVTVTFGKNNNVDP
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCH
TEIILLIQNDKKYRLAGADKLRFTAEMENIEVRINTVKNVLKTLQNRCLPK
HHEEEEEECCCEEEECCCCCEEEEEEECCEEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8465200; 8905232; 9278503 [H]