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The map label for this gene is mltB [H]

Identifier: 161870152

GI number: 161870152

Start: 1180885

End: 1181931

Strand: Reverse

Name: mltB [H]

Synonym: NMCC_1191

Alternate gene names: 161870152

Gene position: 1181931-1180885 (Counterclockwise)

Preceding gene: 161870153

Following gene: 161870150

Centisome position: 54.89

GC content: 55.4

Gene sequence:

>1047_bases
ATGGAGGCACGCCCACCCCGGGCAAATGAAGCCCAAGCCCCCCGCGCGGTTGAAATGAAAAAAGAAAGCCGCCCCGCGTT
TGACGCGGCAGCCGTATTTGACGCGGCAGCCGTACCGGTATCCGACAGCGGGTTTGCCGCCAATGCAAATGTCCGCCGTT
TTGTGGACGATGAAGTCGGGAAAGGGGATTTTTCCCGGGCGGAATGGCAGGATTTTTTTGACAAAGCGGCTTACAAGGCG
GACATCGTCAAGATTATGCACCGCCCCTCCACATCGCGTCCGTGGTATGTGTTCCGCACGGGAAATTCGGGCAAGGCGAA
ATTTCGCGGCGCGCGCCGGTTTTATGCGGAAAACCGCGCGCTTATCGATGATGTGGCGCAAAAATACGGCGTGCCTGCCG
AACTTATCGTGGCGGTTATCGGGATTGAAACGAATTACGGCAAAAATACGGGCAGTTTCCGTGTGGCGGACGCATTGGCG
ACCTTAGGCTTTGATTACCCCCGCCGCGCCGGGTTTTTCCAAAAAGAATTGGTCGAGCTTTTAAAGCTGGCAAAAGAAGA
AGGCGGCGATGTTTTCGCCTTTAAAGGCAGCTATGCGGGCGCAATGGGGATGCCGCAATTTATGCCTTCGAGCTACCGGA
AATGGGCGGTGGATTATGACGGGGACGGACATCGGGACATATGGGGCAACATCGGCGATGTCGCGGCATCGGTTGCCAAT
TATATGAAGCAGCACGGTTGGCGCACGGGCGGGAAAATACTGGTGTCTGCAACATTGGCGCCGGGTGCGGATGTTCAGGC
AATCATTGGCGAAAAAACCGCCCTGACGCGGACGGTGGCGGATTTGAAGGCGTACGGCATCATCCCCGGCGAAGAGCTTG
CCGATGATGAAAAGGCGGTTTTGTTCAAACTGGAAACCGCACCCGGCGTGTTTGAATATTATTTGGGCTTGAACAATTTT
TATACGGTATGGCAGTACAATCACAGTCGGATGTATGTAACGGCGGTCAGGGACATTGCCAATTCGCTCGGCGGCCCGGG
ATTGTAA

Upstream 100 bases:

>100_bases
CGCTTTCCCACTTACCCTATTTGTTCGGAACATATTTATGAAAAAGAGAAAAATACTGCCGCTGGCAATTTGTTTGGCGG
CTTTGTCTGCCTGTACGGCG

Downstream 100 bases:

>100_bases
TGTTTTTTTATAGTGGATTAAATTTGAACCAGTACGGCGTTGCCTCGCCTTGCCGTACTATTTGTACTGTCTACGGCTTC
GTCGCCTTGTCCTGATTTTT

Product: membrane-bound lytic murein transglycosylase B, putative

Products: Muramic Acid Residue [C]

Alternate protein names: 35 kDa soluble lytic transglycosylase; Murein hydrolase B; Slt35 [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MEARPPRANEAQAPRAVEMKKESRPAFDAAAVFDAAAVPVSDSGFAANANVRRFVDDEVGKGDFSRAEWQDFFDKAAYKA
DIVKIMHRPSTSRPWYVFRTGNSGKAKFRGARRFYAENRALIDDVAQKYGVPAELIVAVIGIETNYGKNTGSFRVADALA
TLGFDYPRRAGFFQKELVELLKLAKEEGGDVFAFKGSYAGAMGMPQFMPSSYRKWAVDYDGDGHRDIWGNIGDVAASVAN
YMKQHGWRTGGKILVSATLAPGADVQAIIGEKTALTRTVADLKAYGIIPGEELADDEKAVLFKLETAPGVFEYYLGLNNF
YTVWQYNHSRMYVTAVRDIANSLGGPGL

Sequences:

>Translated_348_residues
MEARPPRANEAQAPRAVEMKKESRPAFDAAAVFDAAAVPVSDSGFAANANVRRFVDDEVGKGDFSRAEWQDFFDKAAYKA
DIVKIMHRPSTSRPWYVFRTGNSGKAKFRGARRFYAENRALIDDVAQKYGVPAELIVAVIGIETNYGKNTGSFRVADALA
TLGFDYPRRAGFFQKELVELLKLAKEEGGDVFAFKGSYAGAMGMPQFMPSSYRKWAVDYDGDGHRDIWGNIGDVAASVAN
YMKQHGWRTGGKILVSATLAPGADVQAIIGEKTALTRTVADLKAYGIIPGEELADDEKAVLFKLETAPGVFEYYLGLNNF
YTVWQYNHSRMYVTAVRDIANSLGGPGL
>Mature_348_residues
MEARPPRANEAQAPRAVEMKKESRPAFDAAAVFDAAAVPVSDSGFAANANVRRFVDDEVGKGDFSRAEWQDFFDKAAYKA
DIVKIMHRPSTSRPWYVFRTGNSGKAKFRGARRFYAENRALIDDVAQKYGVPAELIVAVIGIETNYGKNTGSFRVADALA
TLGFDYPRRAGFFQKELVELLKLAKEEGGDVFAFKGSYAGAMGMPQFMPSSYRKWAVDYDGDGHRDIWGNIGDVAASVAN
YMKQHGWRTGGKILVSATLAPGADVQAIIGEKTALTRTVADLKAYGIIPGEELADDEKAVLFKLETAPGVFEYYLGLNNF
YTVWQYNHSRMYVTAVRDIANSLGGPGL

Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789053, Length=310, Percent_Identity=38.3870967741935, Blast_Score=208, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011757 [H]

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 38220; Mature: 38220

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEARPPRANEAQAPRAVEMKKESRPAFDAAAVFDAAAVPVSDSGFAANANVRRFVDDEVG
CCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCC
KGDFSRAEWQDFFDKAAYKADIVKIMHRPSTSRPWYVFRTGNSGKAKFRGARRFYAENRA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCHH
LIDDVAQKYGVPAELIVAVIGIETNYGKNTGSFRVADALATLGFDYPRRAGFFQKELVEL
HHHHHHHHHCCCHHHHHEEHEEECCCCCCCCCCHHHHHHHHHCCCCCHHCCHHHHHHHHH
LKLAKEEGGDVFAFKGSYAGAMGMPQFMPSSYRKWAVDYDGDGHRDIWGNIGDVAASVAN
HHHHHHCCCCEEEECCCCCCCCCCCHHCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHHH
YMKQHGWRTGGKILVSATLAPGADVQAIIGEKTALTRTVADLKAYGIIPGEELADDEKAV
HHHHCCCCCCCEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCHHHCCCCCEE
LFKLETAPGVFEYYLGLNNFYTVWQYNHSRMYVTAVRDIANSLGGPGL
EEEEECCCCHHHHHHCCCCEEEEEEECCCEEEEHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEARPPRANEAQAPRAVEMKKESRPAFDAAAVFDAAAVPVSDSGFAANANVRRFVDDEVG
CCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCC
KGDFSRAEWQDFFDKAAYKADIVKIMHRPSTSRPWYVFRTGNSGKAKFRGARRFYAENRA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCHH
LIDDVAQKYGVPAELIVAVIGIETNYGKNTGSFRVADALATLGFDYPRRAGFFQKELVEL
HHHHHHHHHCCCHHHHHEEHEEECCCCCCCCCCHHHHHHHHHCCCCCHHCCHHHHHHHHH
LKLAKEEGGDVFAFKGSYAGAMGMPQFMPSSYRKWAVDYDGDGHRDIWGNIGDVAASVAN
HHHHHHCCCCEEEECCCCCCCCCCCHHCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHHH
YMKQHGWRTGGKILVSATLAPGADVQAIIGEKTALTRTVADLKAYGIIPGEELADDEKAV
HHHHCCCCCCCEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCHHHCCCCCEE
LFKLETAPGVFEYYLGLNNFYTVWQYNHSRMYVTAVRDIANSLGGPGL
EEEEECCCCHHHHHHCCCCEEEEEEECCCEEEEHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7476170; 7789526; 9205837; 9278503; 3553176; 9761817; 10570954; 10545329; 10684641 [H]