The gene/protein map for NC_012490 is currently unavailable.
Definition Neisseria meningitidis 053442, complete genome.
Accession NC_010120
Length 2,153,416

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The map label for this gene is dnaJ [H]

Identifier: 161870129

GI number: 161870129

Start: 1159268

End: 1159990

Strand: Reverse

Name: dnaJ [H]

Synonym: NMCC_1168

Alternate gene names: 161870129

Gene position: 1159990-1159268 (Counterclockwise)

Preceding gene: 161870131

Following gene: 161870128

Centisome position: 53.87

GC content: 54.77

Gene sequence:

>723_bases
ATGGACAAAGATTTGTATGCCGTATTGGGCGTGTCGCCGCAGGCGGGTGCGAACGAAATCAAACGCGCCTACCGCAAGCT
GGCGATGAAATACCATCCCGACCGCAATCCGGGCAATCCGCAGGCGGAAGAAAAGTTCAAAGAAATCCAACGGGCTTACG
ATACGCTTTCCGACCTGTCGAAACGGATGCAATACGACGCGTCCTTCAGACGGCATGAGGAACGCGGGCGGCAGGAAGAG
GCATTCCGCCGCGAACAGGCGCGCAGGGAGCAGTTTTACCGCGAACAGATGCGCCGCGAACAGGCGTTCAGACAGGCGTT
TGAACGGCAGGCCTCACGTTCGCGCCATGCTTACGAACCGTCCGGCGGCGGAAGCGGGCGCAACTATGTCCTCGCCGCCT
ACATCCTGTTCGGTTTGGGTGCAATCATGCTGTTCATGCCCATAGTTGGCGTGATTTTCGCCTATATGCCCATAGTCGGC
GTGATTCTCGCCTATATGAAACGGAACAGTTTGGACAGCATTGTCTATGCCACACATACCGAATACCTGATTAAAACCTT
TTGGCGCACATTTTGGCTTTATCTTTTGGGCGCGCTGACTGCCCTTTTGGGTATCGGCGTGCTGATTATTATTGCAACGA
ACGTCTGGTATTTCTACCGCATCATCGTCGGCTTTATCCGCTTCAACAGCGGCAGGGCGGTTGCACCCGAGAAATGGATA
TAG

Upstream 100 bases:

>100_bases
AAAACGCGGGTTCATTATCGGCATCCGTCCCGGAGATTTAAATATTTTGAACCCGAAAACAATACAGGCGGCGGTTTGAC
CGGGAAGTATAAGGAGCAAT

Downstream 100 bases:

>100_bases
TATGGCTTACCTGTTAATCAGCATCGTGTTCAGCGTGTCGGTTTCCATTTTGCTGAAAATGGCAAGGAAGAAAAAAATCG
ACATCGCGCAGGCGGTCGCC

Product: dnaJ-family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MDKDLYAVLGVSPQAGANEIKRAYRKLAMKYHPDRNPGNPQAEEKFKEIQRAYDTLSDLSKRMQYDASFRRHEERGRQEE
AFRREQARREQFYREQMRREQAFRQAFERQASRSRHAYEPSGGGSGRNYVLAAYILFGLGAIMLFMPIVGVIFAYMPIVG
VILAYMKRNSLDSIVYATHTEYLIKTFWRTFWLYLLGALTALLGIGVLIIIATNVWYFYRIIVGFIRFNSGRAVAPEKWI

Sequences:

>Translated_240_residues
MDKDLYAVLGVSPQAGANEIKRAYRKLAMKYHPDRNPGNPQAEEKFKEIQRAYDTLSDLSKRMQYDASFRRHEERGRQEE
AFRREQARREQFYREQMRREQAFRQAFERQASRSRHAYEPSGGGSGRNYVLAAYILFGLGAIMLFMPIVGVIFAYMPIVG
VILAYMKRNSLDSIVYATHTEYLIKTFWRTFWLYLLGALTALLGIGVLIIIATNVWYFYRIIVGFIRFNSGRAVAPEKWI
>Mature_240_residues
MDKDLYAVLGVSPQAGANEIKRAYRKLAMKYHPDRNPGNPQAEEKFKEIQRAYDTLSDLSKRMQYDASFRRHEERGRQEE
AFRREQARREQFYREQMRREQAFRQAFERQASRSRHAYEPSGGGSGRNYVLAAYILFGLGAIMLFMPIVGVIFAYMPIVG
VILAYMKRNSLDSIVYATHTEYLIKTFWRTFWLYLLGALTALLGIGVLIIIATNVWYFYRIIVGFIRFNSGRAVAPEKWI

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG3671

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI7706495, Length=65, Percent_Identity=55.3846153846154, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI201862587, Length=66, Percent_Identity=60.6060606060606, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI201862518, Length=66, Percent_Identity=60.6060606060606, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI56549115, Length=66, Percent_Identity=60.6060606060606, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI45504382, Length=62, Percent_Identity=56.4516129032258, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI24308127, Length=78, Percent_Identity=44.8717948717949, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI29126218, Length=62, Percent_Identity=56.4516129032258, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI6631085, Length=66, Percent_Identity=56.0606060606061, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI9558755, Length=65, Percent_Identity=53.8461538461538, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI5031741, Length=78, Percent_Identity=52.5641025641026, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI205360838, Length=65, Percent_Identity=53.8461538461538, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI205360840, Length=65, Percent_Identity=53.8461538461538, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI4504511, Length=61, Percent_Identity=59.0163934426229, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI72534740, Length=92, Percent_Identity=43.4782608695652, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4885495, Length=64, Percent_Identity=56.25, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI194328760, Length=61, Percent_Identity=59.0163934426229, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI5453690, Length=66, Percent_Identity=57.5757575757576, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI194328758, Length=61, Percent_Identity=59.0163934426229, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI17388799, Length=64, Percent_Identity=56.25, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI23503241, Length=62, Percent_Identity=54.8387096774194, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI47777312, Length=64, Percent_Identity=54.6875, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI8922563, Length=63, Percent_Identity=46.031746031746, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI56687498, Length=99, Percent_Identity=43.4343434343434, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI22749377, Length=93, Percent_Identity=40.8602150537634, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI88501736, Length=62, Percent_Identity=51.6129032258064, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21553335, Length=64, Percent_Identity=51.5625, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI27151736, Length=62, Percent_Identity=51.6129032258064, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI194306642, Length=64, Percent_Identity=53.125, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI194306640, Length=64, Percent_Identity=53.125, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786197, Length=64, Percent_Identity=57.8125, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787235, Length=116, Percent_Identity=36.2068965517241, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554644, Length=65, Percent_Identity=58.4615384615385, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI212645553, Length=74, Percent_Identity=51.3513513513513, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17534355, Length=66, Percent_Identity=59.0909090909091, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17507263, Length=61, Percent_Identity=55.7377049180328, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115532378, Length=76, Percent_Identity=40.7894736842105, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568643, Length=63, Percent_Identity=53.968253968254, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17553096, Length=64, Percent_Identity=50, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17553098, Length=64, Percent_Identity=50, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323870, Length=64, Percent_Identity=50, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322194, Length=72, Percent_Identity=44.4444444444444, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320888, Length=61, Percent_Identity=47.5409836065574, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324265, Length=62, Percent_Identity=56.4516129032258, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324321, Length=62, Percent_Identity=53.2258064516129, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322388, Length=71, Percent_Identity=46.4788732394366, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323813, Length=72, Percent_Identity=47.2222222222222, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324103, Length=63, Percent_Identity=49.2063492063492, Blast_Score=62, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323119, Length=65, Percent_Identity=52.3076923076923, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24658562, Length=66, Percent_Identity=59.0909090909091, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24658555, Length=66, Percent_Identity=59.0909090909091, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45549272, Length=76, Percent_Identity=50, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17737735, Length=62, Percent_Identity=54.8387096774194, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28574723, Length=62, Percent_Identity=54.8387096774194, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45552813, Length=76, Percent_Identity=50, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24668523, Length=62, Percent_Identity=54.8387096774194, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45552811, Length=76, Percent_Identity=50, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646562, Length=61, Percent_Identity=57.3770491803279, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24646560, Length=61, Percent_Identity=57.3770491803279, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24646558, Length=61, Percent_Identity=57.3770491803279, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24646556, Length=61, Percent_Identity=57.3770491803279, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21357547, Length=61, Percent_Identity=57.3770491803279, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI85726398, Length=66, Percent_Identity=56.0606060606061, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24645889, Length=69, Percent_Identity=46.3768115942029, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI18858081, Length=89, Percent_Identity=42.6966292134831, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161077138, Length=65, Percent_Identity=52.3076923076923, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24654066, Length=64, Percent_Identity=51.5625, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654070, Length=64, Percent_Identity=51.5625, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654068, Length=64, Percent_Identity=51.5625, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654072, Length=64, Percent_Identity=51.5625, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641698, Length=68, Percent_Identity=45.5882352941176, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641696, Length=68, Percent_Identity=45.5882352941176, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24668492, Length=76, Percent_Identity=43.421052631579, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129487, Length=78, Percent_Identity=51.2820512820513, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584014, Length=78, Percent_Identity=51.2820512820513, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920464, Length=64, Percent_Identity=45.3125, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 28021; Mature: 28021

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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>Mature Secondary Structure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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA