Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 161870115

GI number: 161870115

Start: 1144157

End: 1145335

Strand: Reverse

Name: hflX [H]

Synonym: NMCC_1154

Alternate gene names: 161870115

Gene position: 1145335-1144157 (Counterclockwise)

Preceding gene: 161870116

Following gene: 161870114

Centisome position: 53.19

GC content: 58.78

Gene sequence:

>1179_bases
ATGACAGGCAGAACAGGCCGCAACGGCAGTACCCAAGCGCAACCGGAACGCGTCATGCTGGTGGGCGTAATGTTGGACAA
AGATGGTACGGGCAGCAGTGCCGCCCGTCTGAACGGTTTTCAGACGGCATTGGCGGAAGCTGTCGAGCTGGTCAAGGCGG
CGGGCGGCGATTCCGTGCGCGTGGAGACTGCCAAACGCGACCGTCCGCACACCGCGCTGTTTGTCGGCACGGGCAAGGCG
GCGGAGCTGTCGGAAGCAGTTGCCGCAGACGGCATCGATTTGGTCGTATTCAACCACGAACTTACGCCCACGCAAGAGCG
CAACCTCGAAAAGGAGCTGAAGTGCCGCGTATTGGACAGGGTGGGGCTGATTCTGGCGATTTTCGCCCGCCGCGCCCGCA
CGCAGGAAGGCAGGCTGCAAGTCGAGTTGGCGCAATTGAGCCATTTGGCGGGACGCTTGATACGCGGTTACGGCCATCTG
CAGAGCCAGCGCGGCGGTATCGGCATGAAAGGGCCGGGCGAAACCAAACTGGAAACCGACCGCCGATTGATCGCCCATCG
AATCAACGCCTTGAAAAAACAGCTTGCCAACCTCAAAAAACAGCGCGCCCTGCGCCGCAAGTCCCGCGAATCGGGCACAA
TCAAAACGTTTGCGCTGGTCGGCTATACCAATGTCGGCAAATCCAGCCTGTTCAACCGGCTGACCAAGTCGGGCATATAT
GCGAAAGACCAGCTTTTCGCCACACTCGACACCACGGCGCGGCGGCTGTACATCAGTCCCGAATGCAGCATCATCCTGAC
CGATACCGTCGGATTCGTCAGCGATCTGCCGCACAAACTGATTTCCGCCTTTTCCGCCACGCTGGAAGAAACCGCGCAAG
CCGATGTGCTGCTGCACGTCGTCGATGCCGCCGCTCCGAACAGCGGACAGCAGATTGAAGACGTGGAAAACGTACTGCGA
GAAATCCATGCCGGCGATATTCTGTGCATCAAGGTGTACAACAAAACCGACCTGCTGCCGTCTGAAGAACAAAACACGGG
CATATGGCGCGACGCTGCGGGAAAAATTGCCGCCGTCCGCATTTCCGTTGCTGAAAATACCGGTATAGACGCACTGCGCG
AAGCCATTGCCGAGTATTGTGCCACCGCACCAAACACAGACGAAACCGAAATGCCATGA

Upstream 100 bases:

>100_bases
ATCGTCTTCAGCGTTGACGGAATGGCGGGCAGCCGCATCACGCTTGCACCGGAAGGAGAAACGGAACGAGGCGTAACCCT
TTATTTACAGGATTGAATAC

Downstream 100 bases:

>100_bases
AAAAAACCTGTTTCCACTGCGGGCTGGACGTTCCCGAAAACCTGCATCTGACCGTCCGTTACGAAAATGAAGACCGCGAA
ACCTGCTGCGCCGGTTGTCA

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTGRTGRNGSTQAQPERVMLVGVMLDKDGTGSSAARLNGFQTALAEAVELVKAAGGDSVRVETAKRDRPHTALFVGTGKA
AELSEAVAADGIDLVVFNHELTPTQERNLEKELKCRVLDRVGLILAIFARRARTQEGRLQVELAQLSHLAGRLIRGYGHL
QSQRGGIGMKGPGETKLETDRRLIAHRINALKKQLANLKKQRALRRKSRESGTIKTFALVGYTNVGKSSLFNRLTKSGIY
AKDQLFATLDTTARRLYISPECSIILTDTVGFVSDLPHKLISAFSATLEETAQADVLLHVVDAAAPNSGQQIEDVENVLR
EIHAGDILCIKVYNKTDLLPSEEQNTGIWRDAAGKIAAVRISVAENTGIDALREAIAEYCATAPNTDETEMP

Sequences:

>Translated_392_residues
MTGRTGRNGSTQAQPERVMLVGVMLDKDGTGSSAARLNGFQTALAEAVELVKAAGGDSVRVETAKRDRPHTALFVGTGKA
AELSEAVAADGIDLVVFNHELTPTQERNLEKELKCRVLDRVGLILAIFARRARTQEGRLQVELAQLSHLAGRLIRGYGHL
QSQRGGIGMKGPGETKLETDRRLIAHRINALKKQLANLKKQRALRRKSRESGTIKTFALVGYTNVGKSSLFNRLTKSGIY
AKDQLFATLDTTARRLYISPECSIILTDTVGFVSDLPHKLISAFSATLEETAQADVLLHVVDAAAPNSGQQIEDVENVLR
EIHAGDILCIKVYNKTDLLPSEEQNTGIWRDAAGKIAAVRISVAENTGIDALREAIAEYCATAPNTDETEMP
>Mature_391_residues
TGRTGRNGSTQAQPERVMLVGVMLDKDGTGSSAARLNGFQTALAEAVELVKAAGGDSVRVETAKRDRPHTALFVGTGKAA
ELSEAVAADGIDLVVFNHELTPTQERNLEKELKCRVLDRVGLILAIFARRARTQEGRLQVELAQLSHLAGRLIRGYGHLQ
SQRGGIGMKGPGETKLETDRRLIAHRINALKKQLANLKKQRALRRKSRESGTIKTFALVGYTNVGKSSLFNRLTKSGIYA
KDQLFATLDTTARRLYISPECSIILTDTVGFVSDLPHKLISAFSATLEETAQADVLLHVVDAAAPNSGQQIEDVENVLRE
IHAGDILCIKVYNKTDLLPSEEQNTGIWRDAAGKIAAVRISVAENTGIDALREAIAEYCATAPNTDETEMP

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=204, Percent_Identity=37.2549019607843, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI310124269, Length=174, Percent_Identity=39.0804597701149, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI310124267, Length=174, Percent_Identity=39.0804597701149, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI310124171, Length=174, Percent_Identity=39.0804597701149, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI310124169, Length=174, Percent_Identity=39.0804597701149, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI310133116, Length=192, Percent_Identity=37.5, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1790615, Length=361, Percent_Identity=49.8614958448753, Blast_Score=335, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI17561038, Length=287, Percent_Identity=32.404181184669, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24650079, Length=334, Percent_Identity=32.9341317365269, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42546; Mature: 42415

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRTGRNGSTQAQPERVMLVGVMLDKDGTGSSAARLNGFQTALAEAVELVKAAGGDSVR
CCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
VETAKRDRPHTALFVGTGKAAELSEAVAADGIDLVVFNHELTPTQERNLEKELKCRVLDR
EEECCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCHHHCHHHHHHHHHHHH
VGLILAIFARRARTQEGRLQVELAQLSHLAGRLIRGYGHLQSQRGGIGMKGPGETKLETD
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
RRLIAHRINALKKQLANLKKQRALRRKSRESGTIKTFALVGYTNVGKSSLFNRLTKSGIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCC
AKDQLFATLDTTARRLYISPECSIILTDTVGFVSDLPHKLISAFSATLEETAQADVLLHV
CHHHHHHHHCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDAAAPNSGQQIEDVENVLREIHAGDILCIKVYNKTDLLPSEEQNTGIWRDAAGKIAAVR
HHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCHHCCCCEEEEE
ISVAENTGIDALREAIAEYCATAPNTDETEMP
EEECCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TGRTGRNGSTQAQPERVMLVGVMLDKDGTGSSAARLNGFQTALAEAVELVKAAGGDSVR
CCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
VETAKRDRPHTALFVGTGKAAELSEAVAADGIDLVVFNHELTPTQERNLEKELKCRVLDR
EEECCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCHHHCHHHHHHHHHHHH
VGLILAIFARRARTQEGRLQVELAQLSHLAGRLIRGYGHLQSQRGGIGMKGPGETKLETD
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
RRLIAHRINALKKQLANLKKQRALRRKSRESGTIKTFALVGYTNVGKSSLFNRLTKSGIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCC
AKDQLFATLDTTARRLYISPECSIILTDTVGFVSDLPHKLISAFSATLEETAQADVLLHV
CHHHHHHHHCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDAAAPNSGQQIEDVENVLREIHAGDILCIKVYNKTDLLPSEEQNTGIWRDAAGKIAAVR
HHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCHHCCCCEEEEE
ISVAENTGIDALREAIAEYCATAPNTDETEMP
EEECCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]