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The map label for this gene is ribC [H]

Identifier: 161870090

GI number: 161870090

Start: 1114753

End: 1115370

Strand: Reverse

Name: ribC [H]

Synonym: NMCC_1128

Alternate gene names: 161870090

Gene position: 1115370-1114753 (Counterclockwise)

Preceding gene: 161870091

Following gene: 161870089

Centisome position: 51.8

GC content: 53.56

Gene sequence:

>618_bases
ATGTTTACAGGCATTGTTCAAGGATTGGGAAAACTGACGGCAATCCACCGCCCGTCGGAGGCATTTCACACTTATGTCGT
CGAGCTTCCGCAAGAGGCGGCGGACAATCTGCAACGCGGCGCATCGGTCGCCAATAACGGCTGCTGCCTGACGATTACCG
AAATCGAAGGAAACCGCGTCAGTTTCGATTTAATGGCGGAAACTTTGGCAAAAACCAATTTGGGGCTGCTGAAGGAAGGC
GATTGCGTCAACATCGAACGGGCGGCGCGTTTCGGAGACGAAATCGGCGGACACGTCATGAGCGGACACATTATGGCAAC
CGTGCCTATTGTCGAAATCGAACGGGACGGGTTCAACCGCACGGTTTGGTTTTCGCTCCCGCATGAACTCAAACCCTATA
TCCTGACCAAAGGGTTCGTCGGCTTGGACGGTTGCAGCCTGACCATAGGCAAAGTCGAAGACGGCCGTTTCAATGTCCAT
CTGATTCCCGAAACTTTGGAACGGACGCTGTTCGGCAGCAGAAAGGTCGGCGACAGGATCAACATCGAAATCGATCCGAA
TACGCAGGCAATCGTCGATACCGTCGAACGGCTGATGGCGCAAAGATATGCAAAGTGA

Upstream 100 bases:

>100_bases
AATCGGAGGCATAATGCTGTCTGAAGGCATTTCAGACGGCATTTTTCGCGGGGAGATGCTACAATTTGCACCATTTTTAC
CGACACAGGGAAACAGGATT

Downstream 100 bases:

>100_bases
GGCAGAGATGGAATTGAACGAATTTCTCGATAAAGCCTATGCCGTTTTGCGGCGTTTGGATGCCGTGCTTCCGCCCGAAC
CCGGGCATACGGATTGGAAC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MFTGIVQGLGKLTAIHRPSEAFHTYVVELPQEAADNLQRGASVANNGCCLTITEIEGNRVSFDLMAETLAKTNLGLLKEG
DCVNIERAARFGDEIGGHVMSGHIMATVPIVEIERDGFNRTVWFSLPHELKPYILTKGFVGLDGCSLTIGKVEDGRFNVH
LIPETLERTLFGSRKVGDRINIEIDPNTQAIVDTVERLMAQRYAK

Sequences:

>Translated_205_residues
MFTGIVQGLGKLTAIHRPSEAFHTYVVELPQEAADNLQRGASVANNGCCLTITEIEGNRVSFDLMAETLAKTNLGLLKEG
DCVNIERAARFGDEIGGHVMSGHIMATVPIVEIERDGFNRTVWFSLPHELKPYILTKGFVGLDGCSLTIGKVEDGRFNVH
LIPETLERTLFGSRKVGDRINIEIDPNTQAIVDTVERLMAQRYAK
>Mature_205_residues
MFTGIVQGLGKLTAIHRPSEAFHTYVVELPQEAADNLQRGASVANNGCCLTITEIEGNRVSFDLMAETLAKTNLGLLKEG
DCVNIERAARFGDEIGGHVMSGHIMATVPIVEIERDGFNRTVWFSLPHELKPYILTKGFVGLDGCSLTIGKVEDGRFNVH
LIPETLERTLFGSRKVGDRINIEIDPNTQAIVDTVERLMAQRYAK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=204, Percent_Identity=62.7450980392157, Blast_Score=253, Evalue=9e-69,
Organism=Saccharomyces cerevisiae, GI6319733, Length=195, Percent_Identity=33.8461538461538, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22582; Mature: 22582

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVQGLGKLTAIHRPSEAFHTYVVELPQEAADNLQRGASVANNGCCLTITEIEGNRV
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCEE
SFDLMAETLAKTNLGLLKEGDCVNIERAARFGDEIGGHVMSGHIMATVPIVEIERDGFNR
EHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCEEEEEEEEEEEECCCCCE
TVWFSLPHELKPYILTKGFVGLDGCSLTIGKVEDGRFNVHLIPETLERTLFGSRKVGDRI
EEEEECCCCCCCEEEECCCCCCCCCEEEEEEECCCEEEEEECHHHHHHHHCCCCCCCCEE
NIEIDPNTQAIVDTVERLMAQRYAK
EEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTGIVQGLGKLTAIHRPSEAFHTYVVELPQEAADNLQRGASVANNGCCLTITEIEGNRV
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCEE
SFDLMAETLAKTNLGLLKEGDCVNIERAARFGDEIGGHVMSGHIMATVPIVEIERDGFNR
EHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCEEEEEEEEEEEECCCCCE
TVWFSLPHELKPYILTKGFVGLDGCSLTIGKVEDGRFNVHLIPETLERTLFGSRKVGDRI
EEEEECCCCCCCEEEECCCCCCCCCEEEEEEECCCEEEEEECHHHHHHHHCCCCCCCCEE
NIEIDPNTQAIVDTVERLMAQRYAK
EEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9022701; 9023191; 9097039; 9278503; 11377200 [H]