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The map label for this gene is ppiD [H]

Identifier: 161870081

GI number: 161870081

Start: 1105806

End: 1107344

Strand: Reverse

Name: ppiD [H]

Synonym: NMCC_1119

Alternate gene names: 161870081

Gene position: 1107344-1105806 (Counterclockwise)

Preceding gene: 161870083

Following gene: 161870080

Centisome position: 51.42

GC content: 52.7

Gene sequence:

>1539_bases
ATGTTCCATTCCATCGAAAAATACAGAACGCCCGCCCAAGTCTTATTAGGCCTGATTGCATTGACCTTCGTCGGCTTCGG
GGTCAGCACGGTATCCCATCCGGGCGCCGACTACATCGTCCAAGTGGGCGACGAAAAAATCAGCGAGCAGTCGCTTAACG
CCGCCGTCCAAAACGAGCAGGCGGACGGCGGCAGCCCTTCGCGCGACGCGGTGTTCCAATCCCTGCTACAACGCGCCTAC
CTGAAACAGGGCGCGAAGCTGATGGGCATTTCGGTTTCTTCCGAACAAATCAAGCAGATTATCGTGGACGATCCCAATTT
CCACGACGCAAACGGCAAATTCGACCACGCGCTTTTAAACCGCTACCTGTCGCAACGCCATATGTCTGAAGACCAGTTTG
TCGAAGAAATCCGCGATCAGTTTGCCTTGCAGAATTTGGTAAACCTCGTCCAAAACGGCGTATTGGTCGGCGACGCGCAG
GCGGAACAGCTGATCAGGCTGACGCAGGTCAACCGCACCATCCGTTCGCACACTTTCAACCCCGACGAATTCATCGCCCA
AGTCAAAGTGTCTGAAGCCGATTTGCAGAAGTTTTATAACGCAAACAAAAAAGACTACCTGCTTCCCAAAGCGGTCAAAT
TGGAATATGTCGCATTGAATCTGAAAGACTTTGCAGACAAACAGACCGTCAGCGAAACAGAAGTGAAAAATGCGTTTGAA
GAGCGCGTGGCGCGTTTGCCGGCAAATGAAGCCAAACCTTCTTTCGAGCAGGAAAAAGCCGCCGTAGAAAACGAATTGAA
AATGAAAAAGGCGGTTGCCGACTTCAATAAGGCAAAAGAAAAGCTGGGCGATGACGCGTTCAACCATCCTTCCTCGCTTG
CCGAAGCCGCCAAAAACAGCGGTTTGAAAGTCGAAACCCAAGAAACTTGGCTGAGCAGGCAGGATGCGCAAATGTCCGGT
ATGCCCGAAAACCTGATCAATGCCGTATTCAGCGACGACGTATTGAAGAAAAAACACAATTCCGAAGTACTGACCATCAA
CAGCGAAACCGCGTGGGTCGTCCGCGCCAAAGAAGTCCGCGAAGAGAAAACCCTGCCGTTTGCCGAAGCCAAAGACGCGG
TACGTCAGGCTTATATCCGTACCGAAGCCGCCAAACTTGCCGAAAACAAGGCAAAAGACGTGCTTACCCAACTGAACGGC
GGCAAGGCTGTTGACGTGAAATGGTCGGAAGTGTCCGTTTTGGGCGCACAGCAGGCAAGGCAGTCCATGCCGCCCGAGGC
TTATGCGGAACTGCTGAAAGCAAAACCGGCAAACGGCAAACCCGCCTACGTCAGGCTGATCGGTCTGCCGGCACCCGTGA
TTGTCGAAGTACAGGCTGTAACCCCGCCGGATGATATCGCCGCACAGCTTCCGCTTGCAAAACAGGCTTTGGCGCAACAG
CAGTCTGCCAATACTTTCGACTTGTTGATACGTTATTTCAACGGCAAAATCAAACAGACCAAAGGAGCGCAATCGGTCGA
CAACGGCGACGCTCAGTAA

Upstream 100 bases:

>100_bases
CGAGAGATATTCAAACGTTAGTTAAGCCTTCGTGCAGGCGCGTATAAAAACCGTTACAATACCCGACTTGAATTTCCCAT
TCTATATCCCGATTTAAAAT

Downstream 100 bases:

>100_bases
TTGACACTTTTGTTGACAAAATAACGGTCGGAATATTCCGGCCGTTTTCCCATACGGCGGAATATGATGAGCCACAAAAA
ACAAGATGCCTTCCAAGGAT

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MFHSIEKYRTPAQVLLGLIALTFVGFGVSTVSHPGADYIVQVGDEKISEQSLNAAVQNEQADGGSPSRDAVFQSLLQRAY
LKQGAKLMGISVSSEQIKQIIVDDPNFHDANGKFDHALLNRYLSQRHMSEDQFVEEIRDQFALQNLVNLVQNGVLVGDAQ
AEQLIRLTQVNRTIRSHTFNPDEFIAQVKVSEADLQKFYNANKKDYLLPKAVKLEYVALNLKDFADKQTVSETEVKNAFE
ERVARLPANEAKPSFEQEKAAVENELKMKKAVADFNKAKEKLGDDAFNHPSSLAEAAKNSGLKVETQETWLSRQDAQMSG
MPENLINAVFSDDVLKKKHNSEVLTINSETAWVVRAKEVREEKTLPFAEAKDAVRQAYIRTEAAKLAENKAKDVLTQLNG
GKAVDVKWSEVSVLGAQQARQSMPPEAYAELLKAKPANGKPAYVRLIGLPAPVIVEVQAVTPPDDIAAQLPLAKQALAQQ
QSANTFDLLIRYFNGKIKQTKGAQSVDNGDAQ

Sequences:

>Translated_512_residues
MFHSIEKYRTPAQVLLGLIALTFVGFGVSTVSHPGADYIVQVGDEKISEQSLNAAVQNEQADGGSPSRDAVFQSLLQRAY
LKQGAKLMGISVSSEQIKQIIVDDPNFHDANGKFDHALLNRYLSQRHMSEDQFVEEIRDQFALQNLVNLVQNGVLVGDAQ
AEQLIRLTQVNRTIRSHTFNPDEFIAQVKVSEADLQKFYNANKKDYLLPKAVKLEYVALNLKDFADKQTVSETEVKNAFE
ERVARLPANEAKPSFEQEKAAVENELKMKKAVADFNKAKEKLGDDAFNHPSSLAEAAKNSGLKVETQETWLSRQDAQMSG
MPENLINAVFSDDVLKKKHNSEVLTINSETAWVVRAKEVREEKTLPFAEAKDAVRQAYIRTEAAKLAENKAKDVLTQLNG
GKAVDVKWSEVSVLGAQQARQSMPPEAYAELLKAKPANGKPAYVRLIGLPAPVIVEVQAVTPPDDIAAQLPLAKQALAQQ
QSANTFDLLIRYFNGKIKQTKGAQSVDNGDAQ
>Mature_512_residues
MFHSIEKYRTPAQVLLGLIALTFVGFGVSTVSHPGADYIVQVGDEKISEQSLNAAVQNEQADGGSPSRDAVFQSLLQRAY
LKQGAKLMGISVSSEQIKQIIVDDPNFHDANGKFDHALLNRYLSQRHMSEDQFVEEIRDQFALQNLVNLVQNGVLVGDAQ
AEQLIRLTQVNRTIRSHTFNPDEFIAQVKVSEADLQKFYNANKKDYLLPKAVKLEYVALNLKDFADKQTVSETEVKNAFE
ERVARLPANEAKPSFEQEKAAVENELKMKKAVADFNKAKEKLGDDAFNHPSSLAEAAKNSGLKVETQETWLSRQDAQMSG
MPENLINAVFSDDVLKKKHNSEVLTINSETAWVVRAKEVREEKTLPFAEAKDAVRQAYIRTEAAKLAENKAKDVLTQLNG
GKAVDVKWSEVSVLGAQQARQSMPPEAYAELLKAKPANGKPAYVRLIGLPAPVIVEVQAVTPPDDIAAQLPLAKQALAQQ
QSANTFDLLIRYFNGKIKQTKGAQSVDNGDAQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=594, Percent_Identity=22.3905723905724, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 56584; Mature: 56584

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHSIEKYRTPAQVLLGLIALTFVGFGVSTVSHPGADYIVQVGDEKISEQSLNAAVQNEQ
CCCCCHHHCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCC
ADGGSPSRDAVFQSLLQRAYLKQGAKLMGISVSSEQIKQIIVDDPNFHDANGKFDHALLN
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHHH
RYLSQRHMSEDQFVEEIRDQFALQNLVNLVQNGVLVGDAQAEQLIRLTQVNRTIRSHTFN
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHCCCC
PDEFIAQVKVSEADLQKFYNANKKDYLLPKAVKLEYVALNLKDFADKQTVSETEVKNAFE
HHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHEEEEEEECHHHHHHHHHHHHHHHHHHHH
ERVARLPANEAKPSFEQEKAAVENELKMKKAVADFNKAKEKLGDDAFNHPSSLAEAAKNS
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
GLKVETQETWLSRQDAQMSGMPENLINAVFSDDVLKKKHNSEVLTINSETAWVVRAKEVR
CCEEEHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEHHHHH
EEKTLPFAEAKDAVRQAYIRTEAAKLAENKAKDVLTQLNGGKAVDVKWSEVSVLGAQQAR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
QSMPPEAYAELLKAKPANGKPAYVRLIGLPAPVIVEVQAVTPPDDIAAQLPLAKQALAQQ
HCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHCCHHHHHHHHH
QSANTFDLLIRYFNGKIKQTKGAQSVDNGDAQ
HCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFHSIEKYRTPAQVLLGLIALTFVGFGVSTVSHPGADYIVQVGDEKISEQSLNAAVQNEQ
CCCCCHHHCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCC
ADGGSPSRDAVFQSLLQRAYLKQGAKLMGISVSSEQIKQIIVDDPNFHDANGKFDHALLN
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHHH
RYLSQRHMSEDQFVEEIRDQFALQNLVNLVQNGVLVGDAQAEQLIRLTQVNRTIRSHTFN
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHCCCC
PDEFIAQVKVSEADLQKFYNANKKDYLLPKAVKLEYVALNLKDFADKQTVSETEVKNAFE
HHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHEEEEEEECHHHHHHHHHHHHHHHHHHHH
ERVARLPANEAKPSFEQEKAAVENELKMKKAVADFNKAKEKLGDDAFNHPSSLAEAAKNS
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
GLKVETQETWLSRQDAQMSGMPENLINAVFSDDVLKKKHNSEVLTINSETAWVVRAKEVR
CCEEEHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEHHHHH
EEKTLPFAEAKDAVRQAYIRTEAAKLAENKAKDVLTQLNGGKAVDVKWSEVSVLGAQQAR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
QSMPPEAYAELLKAKPANGKPAYVRLIGLPAPVIVEVQAVTPPDDIAAQLPLAKQALAQQ
HCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHCCHHHHHHHHH
QSANTFDLLIRYFNGKIKQTKGAQSVDNGDAQ
HCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]