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The map label for this gene is hgiDIIM [H]

Identifier: 161870058

GI number: 161870058

Start: 1077592

End: 1078614

Strand: Direct

Name: hgiDIIM [H]

Synonym: NMCC_1094

Alternate gene names: 161870058

Gene position: 1077592-1078614 (Clockwise)

Preceding gene: 161870057

Following gene: 161870061

Centisome position: 50.04

GC content: 40.86

Gene sequence:

>1023_bases
ATGAAAATTGAAGCAGTAGATTTATTTTGTGGAGCAGGTGGGTTGACAGCAGGTTTACTTCGAGCAGGAATTAAAGTGAA
AGCTGGATATGATATTGATGCAGCTTGTGCATATGCGTACGAGTATAACAATAAAGGTGCAAAATTTATATTACAAGATG
TGGAAACAGTTACTGGAGATCAGATTCAGGCGCACTATTCAAAAGATGCAGTTAGATTATTAGCTGGTTGTGCTCCTTGT
CAGCCATTTTCTACTTACAATCAAGGTCGTGATGTTCGTAATGACAAAAAATGGCCATTACTATACGCTTTTTCTCGCTT
GATTCATGAAGTGCAACCAGAGCTTGTGACTATGGAGAATGTGCCAGATGTTGTAAAACATGAGGTATACCAAGATTTTG
TAAATAATTTAAAACAACAGGGATACCAAGTTTGGGCTGAAAAAGTATTATGTGCAGATTATGGAGTCCCTCAATCACGA
CGTAGACACGTATTACTTGCATCACGTATCGGTAATATTCAGATGGTTCCTCCAACGCATTCAAATTGCCATGTAACAGT
TCGTCAGGCTATTGGACACTTGCCGCCACTGGCAGCAGGCAAACAAGATACTATAGATGTATTACATCGGTGTTCATCAA
TGTCAGCTCGTAATCTAGAACGGATTCGTGCTTCTCGTCCAGGAGGAACATGGATGGATTGGCCAGAAGATTTACGAGCC
GCATGTCATCGCAAAAAAAAAGGACAGTCTTATAAACGAATTTATGGTCGTATGGAATGGGACAAGCCCGCCCCAACAAT
GACAACTTTATGTATTGGCTTCGGCAATGGACGCTTTGGGCATCCGGAACAAGACCGTGCAATTTCTTTAAGGGAGGCAG
CCTTATTCCAAAGTTTTCCTCTAGATTACCAGTTCACTCAAGAAACTGATACTCCAATTCGCCAAATTAGTCGAATGATT
GGTAATGCTGTTCCTGTATTGCTAGGTGAGGCAATCGGAAATAGTTTTAAACTGTTGGTTTGA

Upstream 100 bases:

>100_bases
TCATAAGGAACTGTACTATTCAGAGCTTATATACTATTAAAAGCTCGACTCCAATCAAAGTTAAGGATATAATCCTTATA
TCAAAAATATGAGTTGAAAA

Downstream 100 bases:

>100_bases
GATATTTCTTCTGCATTAGATATTCAGTAAATGCATCAGTAAATAAATGCATATAGCGGAAAGTAGTGTCTTTTATTGCC
ATTAAATCAGATATTGTTCG

Product: modification methylase (cytosine-specific DNA methylase)

Products: NA

Alternate protein names: M.HgiDII; Cytosine-specific methyltransferase HgiDII [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKIEAVDLFCGAGGLTAGLLRAGIKVKAGYDIDAACAYAYEYNNKGAKFILQDVETVTGDQIQAHYSKDAVRLLAGCAPC
QPFSTYNQGRDVRNDKKWPLLYAFSRLIHEVQPELVTMENVPDVVKHEVYQDFVNNLKQQGYQVWAEKVLCADYGVPQSR
RRHVLLASRIGNIQMVPPTHSNCHVTVRQAIGHLPPLAAGKQDTIDVLHRCSSMSARNLERIRASRPGGTWMDWPEDLRA
ACHRKKKGQSYKRIYGRMEWDKPAPTMTTLCIGFGNGRFGHPEQDRAISLREAALFQSFPLDYQFTQETDTPIRQISRMI
GNAVPVLLGEAIGNSFKLLV

Sequences:

>Translated_340_residues
MKIEAVDLFCGAGGLTAGLLRAGIKVKAGYDIDAACAYAYEYNNKGAKFILQDVETVTGDQIQAHYSKDAVRLLAGCAPC
QPFSTYNQGRDVRNDKKWPLLYAFSRLIHEVQPELVTMENVPDVVKHEVYQDFVNNLKQQGYQVWAEKVLCADYGVPQSR
RRHVLLASRIGNIQMVPPTHSNCHVTVRQAIGHLPPLAAGKQDTIDVLHRCSSMSARNLERIRASRPGGTWMDWPEDLRA
ACHRKKKGQSYKRIYGRMEWDKPAPTMTTLCIGFGNGRFGHPEQDRAISLREAALFQSFPLDYQFTQETDTPIRQISRMI
GNAVPVLLGEAIGNSFKLLV
>Mature_340_residues
MKIEAVDLFCGAGGLTAGLLRAGIKVKAGYDIDAACAYAYEYNNKGAKFILQDVETVTGDQIQAHYSKDAVRLLAGCAPC
QPFSTYNQGRDVRNDKKWPLLYAFSRLIHEVQPELVTMENVPDVVKHEVYQDFVNNLKQQGYQVWAEKVLCADYGVPQSR
RRHVLLASRIGNIQMVPPTHSNCHVTVRQAIGHLPPLAAGKQDTIDVLHRCSSMSARNLERIRASRPGGTWMDWPEDLRA
ACHRKKKGQSYKRIYGRMEWDKPAPTMTTLCIGFGNGRFGHPEQDRAISLREAALFQSFPLDYQFTQETDTPIRQISRMI
GNAVPVLLGEAIGNSFKLLV

Specific function: This methylase recognizes the double-stranded sequence GTCGAC, causes specific methylation on C-? on both strands and protects the DNA from cleavage by the HgiDII endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 38106; Mature: 38106

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS01109 RIBOSOMAL_L10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEAVDLFCGAGGLTAGLLRAGIKVKAGYDIDAACAYAYEYNNKGAKFILQDVETVTGD
CCCEEEEEEECCCHHHHHHHHCCCEEECCCCCCHHEEEEEEECCCCHHHHHHHHHHHCCC
QIQAHYSKDAVRLLAGCAPCQPFSTYNQGRDVRNDKKWPLLYAFSRLIHEVQPELVTMEN
HHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCC
VPDVVKHEVYQDFVNNLKQQGYQVWAEKVLCADYGVPQSRRRHVLLASRIGNIQMVPPTH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEEEEECCCCEEECCCCC
SNCHVTVRQAIGHLPPLAAGKQDTIDVLHRCSSMSARNLERIRASRPGGTWMDWPEDLRA
CCCEEEHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHH
ACHRKKKGQSYKRIYGRMEWDKPAPTMTTLCIGFGNGRFGHPEQDRAISLREAALFQSFP
HHHHHHCCCHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
LDYQFTQETDTPIRQISRMIGNAVPVLLGEAIGNSFKLLV
CCEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MKIEAVDLFCGAGGLTAGLLRAGIKVKAGYDIDAACAYAYEYNNKGAKFILQDVETVTGD
CCCEEEEEEECCCHHHHHHHHCCCEEECCCCCCHHEEEEEEECCCCHHHHHHHHHHHCCC
QIQAHYSKDAVRLLAGCAPCQPFSTYNQGRDVRNDKKWPLLYAFSRLIHEVQPELVTMEN
HHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCC
VPDVVKHEVYQDFVNNLKQQGYQVWAEKVLCADYGVPQSRRRHVLLASRIGNIQMVPPTH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEEEEECCCCEEECCCCC
SNCHVTVRQAIGHLPPLAAGKQDTIDVLHRCSSMSARNLERIRASRPGGTWMDWPEDLRA
CCCEEEHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHH
ACHRKKKGQSYKRIYGRMEWDKPAPTMTTLCIGFGNGRFGHPEQDRAISLREAALFQSFP
HHHHHHCCCHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
LDYQFTQETDTPIRQISRMIGNAVPVLLGEAIGNSFKLLV
CCEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1937045; 7607523 [H]