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The map label for this gene is cysH [H]

Identifier: 161870040

GI number: 161870040

Start: 1055780

End: 1056553

Strand: Reverse

Name: cysH [H]

Synonym: NMCC_1073

Alternate gene names: 161870040

Gene position: 1056553-1055780 (Counterclockwise)

Preceding gene: 161870041

Following gene: 161870039

Centisome position: 49.06

GC content: 58.27

Gene sequence:

>774_bases
ATGCCGGACAACGGGCGGCATAAGGCGGGAAAAATGGAAACGACACTGTTCAAACCCGCCCTGTGGCAGATACCGCATAT
CGGATCCGGCGGCGAAACCGCCCTTGCGGAAAAAACGGAAACCCTCAAACAACGCCTGCACCGGATTGTCGGCAGCCACC
GGGATGCACGGTTTGCCAGCAGCCTTGCGGCAGAAGATATGGTGATTACCGACCTTATCGCCGGCGAAAACCTCAATATC
GGCATTTTTACCTTGGATACGGGGCTGCTCCACACGGAAACCCTAAACCTGCTGGACAGGCTCGGACGCGCATATCCCCA
TTTGCGGATAAAGCGTTTCCGGCCGGTTCGAGAAGATGCCGACCGTTATGTGGAAAGCAAAGGCAGGTTTGCCTTTTACG
ACAGCGTTGAAGCGCGCCGCGAATGCTGCCGCATCCGAAAAATCGAACCGCTCAACCGCGCCATTGCAGGCGCGGACGCC
TGGCTTACCGGGCAACGCCGCGAACAATCCGCCACACGCACGGAACTGCCGTTTGCCGAATACGATGCCGGACGGGGCAT
CGGCAAATACAACCCGATTTTCGACTGGTCGGAACACGACGTGTGGGCATACATCCTCGCCAACAATGTGCCTTACAACG
ATTTGTACCGGCAAGGATTTCCCAGCATAGGCTGCGACCCCTGCACCCGCCCCGTCAAGGCGGGCGAAGACATCCGCGCC
GGGCGGTGGTGGTGGGAAGGCAGAAACAGCAAAGAATGCGGGCTGCACAAATAA

Upstream 100 bases:

>100_bases
GGCGAAGTGGTGGGGCTGCACGAAAAACTCGCCTGGTTCGGTGAAAACGGCGAAGGAGAAAACCGGGTCGGGCAGGCGTA
TCCCGCATTGGGCGGACTGA

Downstream 100 bases:

>100_bases
TTCATAAATATCAGACAGAAGAAATAAGGAATATGGTATGACGAAAACCGAACCGAACAACGCCCAACTCGACTGGTTGG
AATCCGAATCCATCCACATC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MPDNGRHKAGKMETTLFKPALWQIPHIGSGGETALAEKTETLKQRLHRIVGSHRDARFASSLAAEDMVITDLIAGENLNI
GIFTLDTGLLHTETLNLLDRLGRAYPHLRIKRFRPVREDADRYVESKGRFAFYDSVEARRECCRIRKIEPLNRAIAGADA
WLTGQRREQSATRTELPFAEYDAGRGIGKYNPIFDWSEHDVWAYILANNVPYNDLYRQGFPSIGCDPCTRPVKAGEDIRA
GRWWWEGRNSKECGLHK

Sequences:

>Translated_257_residues
MPDNGRHKAGKMETTLFKPALWQIPHIGSGGETALAEKTETLKQRLHRIVGSHRDARFASSLAAEDMVITDLIAGENLNI
GIFTLDTGLLHTETLNLLDRLGRAYPHLRIKRFRPVREDADRYVESKGRFAFYDSVEARRECCRIRKIEPLNRAIAGADA
WLTGQRREQSATRTELPFAEYDAGRGIGKYNPIFDWSEHDVWAYILANNVPYNDLYRQGFPSIGCDPCTRPVKAGEDIRA
GRWWWEGRNSKECGLHK
>Mature_256_residues
PDNGRHKAGKMETTLFKPALWQIPHIGSGGETALAEKTETLKQRLHRIVGSHRDARFASSLAAEDMVITDLIAGENLNIG
IFTLDTGLLHTETLNLLDRLGRAYPHLRIKRFRPVREDADRYVESKGRFAFYDSVEARRECCRIRKIEPLNRAIAGADAW
LTGQRREQSATRTELPFAEYDAGRGIGKYNPIFDWSEHDVWAYILANNVPYNDLYRQGFPSIGCDPCTRPVKAGEDIRAG
RWWWEGRNSKECGLHK

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=202, Percent_Identity=30.1980198019802, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325425, Length=115, Percent_Identity=45.2173913043478, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 29295; Mature: 29164

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDNGRHKAGKMETTLFKPALWQIPHIGSGGETALAEKTETLKQRLHRIVGSHRDARFAS
CCCCCCCCCCCCHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SLAAEDMVITDLIAGENLNIGIFTLDTGLLHTETLNLLDRLGRAYPHLRIKRFRPVREDA
HHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHH
DRYVESKGRFAFYDSVEARRECCRIRKIEPLNRAIAGADAWLTGQRREQSATRTELPFAE
HHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHCCCHHCCCCHHHHHHHHHCCCCHH
YDAGRGIGKYNPIFDWSEHDVWAYILANNVPYNDLYRQGFPSIGCDPCTRPVKAGEDIRA
HCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
GRWWWEGRNSKECGLHK
CCEEECCCCCCCCCCCC
>Mature Secondary Structure 
PDNGRHKAGKMETTLFKPALWQIPHIGSGGETALAEKTETLKQRLHRIVGSHRDARFAS
CCCCCCCCCCCHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SLAAEDMVITDLIAGENLNIGIFTLDTGLLHTETLNLLDRLGRAYPHLRIKRFRPVREDA
HHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHH
DRYVESKGRFAFYDSVEARRECCRIRKIEPLNRAIAGADAWLTGQRREQSATRTELPFAE
HHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHCCCHHCCCCHHHHHHHHHCCCCHH
YDAGRGIGKYNPIFDWSEHDVWAYILANNVPYNDLYRQGFPSIGCDPCTRPVKAGEDIRA
HCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
GRWWWEGRNSKECGLHK
CCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]