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The map label for this gene is yciK [H]

Identifier: 161870014

GI number: 161870014

Start: 1030344

End: 1031063

Strand: Reverse

Name: yciK [H]

Synonym: NMCC_1047

Alternate gene names: 161870014

Gene position: 1031063-1030344 (Counterclockwise)

Preceding gene: 161870015

Following gene: 161870013

Centisome position: 47.88

GC content: 59.03

Gene sequence:

>720_bases
ATGGCGACACTGTCCGACAAAACCATCTTAATTACCGGCGCATCGCAAGGTCTGGGCGAACAGGTCGCCAAAGCCTATGC
GGCGGCAGGCGCAACCGTGATTCTGGTGGCACGCCATCAGAAAAAACTGGAAAAAGTCTATGACGCGATTGTCGAAGCCG
GACACCCCGAACCCTTCGCCATCCGTTTCGACCTGATGAGTGCGGAAGAAAAAGAATTCAATCAGTTCGCCGCCACCATT
GCCGAAGCCACGCAAGGCAAACTGGACGGCATCGTCCACTGCGCCGGCTATTTTTACGCCCTCTCGCCGCTGGATTTCCA
AACCGTCGCCGAATGGGTCAACCAATACCGCATCAACACCGTCGCACCTATGGGGCTGACCCGCGCCCTGTTCCCGCTGC
TGAAGCAGTCGCCCGACGCGTCCGTCATCTTCGTCGGCGAAAGCCACGGCGAAACACCCAAAGCCTACTGGGGCGGCTTC
GGCGCGTCCAAAGCCGCGTTGAACTACCTGTGCAAAGTCGCCGCCGACGAATGGGAACACTTCGGCAACCTGCGCGCCAA
CGTCCTCGTCCCCGGACCCATCAATTCCCCGCAACGCATCAAATCCCATCCGGGCGAAGCCAAAAGCGAACGCAAAAGCT
ACGGGGACGTGCTGCCCGCATTTGTCTGGTGGGCAAGTGCCGAAAGCAAAGGGCGGAGCGGCGAAATCGTTTACCTCTAA

Upstream 100 bases:

>100_bases
TGAGCGATGCCGTCTGAAAACGCCGGCCGGCATCGGGACGCTTTACAAGGTGCGGCAAAACGCTAAAATACCCCCGACCG
ACCACCAAAAAGGAAAAAGT

Downstream 100 bases:

>100_bases
ATCCGGAAAAGGCAGGCATCCCGCCCGCGCCGCGATTCCGTTTGAAAAATATCCGTACCTTCCGTGCGCATCCGTCCCGC
ACAGACAAACACCTTGACTT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MATLSDKTILITGASQGLGEQVAKAYAAAGATVILVARHQKKLEKVYDAIVEAGHPEPFAIRFDLMSAEEKEFNQFAATI
AEATQGKLDGIVHCAGYFYALSPLDFQTVAEWVNQYRINTVAPMGLTRALFPLLKQSPDASVIFVGESHGETPKAYWGGF
GASKAALNYLCKVAADEWEHFGNLRANVLVPGPINSPQRIKSHPGEAKSERKSYGDVLPAFVWWASAESKGRSGEIVYL

Sequences:

>Translated_239_residues
MATLSDKTILITGASQGLGEQVAKAYAAAGATVILVARHQKKLEKVYDAIVEAGHPEPFAIRFDLMSAEEKEFNQFAATI
AEATQGKLDGIVHCAGYFYALSPLDFQTVAEWVNQYRINTVAPMGLTRALFPLLKQSPDASVIFVGESHGETPKAYWGGF
GASKAALNYLCKVAADEWEHFGNLRANVLVPGPINSPQRIKSHPGEAKSERKSYGDVLPAFVWWASAESKGRSGEIVYL
>Mature_238_residues
ATLSDKTILITGASQGLGEQVAKAYAAAGATVILVARHQKKLEKVYDAIVEAGHPEPFAIRFDLMSAEEKEFNQFAATIA
EATQGKLDGIVHCAGYFYALSPLDFQTVAEWVNQYRINTVAPMGLTRALFPLLKQSPDASVIFVGESHGETPKAYWGGFG
ASKAALNYLCKVAADEWEHFGNLRANVLVPGPINSPQRIKSHPGEAKSERKSYGDVLPAFVWWASAESKGRSGEIVYL

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787526, Length=231, Percent_Identity=34.6320346320346, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87082100, Length=201, Percent_Identity=28.8557213930348, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25152911, Length=178, Percent_Identity=27.5280898876405, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=29.6482412060301, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=199, Percent_Identity=26.1306532663317, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI45553409, Length=211, Percent_Identity=29.8578199052133, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647948, Length=211, Percent_Identity=29.8578199052133, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647946, Length=211, Percent_Identity=29.8578199052133, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25933; Mature: 25801

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLSDKTILITGASQGLGEQVAKAYAAAGATVILVARHQKKLEKVYDAIVEAGHPEPFA
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEE
IRFDLMSAEEKEFNQFAATIAEATQGKLDGIVHCAGYFYALSPLDFQTVAEWVNQYRINT
EEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCE
VAPMGLTRALFPLLKQSPDASVIFVGESHGETPKAYWGGFGASKAALNYLCKVAADEWEH
ECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
FGNLRANVLVPGPINSPQRIKSHPGEAKSERKSYGDVLPAFVWWASAESKGRSGEIVYL
HCCCEEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
>Mature Secondary Structure 
ATLSDKTILITGASQGLGEQVAKAYAAAGATVILVARHQKKLEKVYDAIVEAGHPEPFA
CCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEE
IRFDLMSAEEKEFNQFAATIAEATQGKLDGIVHCAGYFYALSPLDFQTVAEWVNQYRINT
EEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCE
VAPMGLTRALFPLLKQSPDASVIFVGESHGETPKAYWGGFGASKAALNYLCKVAADEWEH
ECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
FGNLRANVLVPGPINSPQRIKSHPGEAKSERKSYGDVLPAFVWWASAESKGRSGEIVYL
HCCCEEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]