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The map label for this gene is insK [H]

Identifier: 161869926

GI number: 161869926

Start: 958728

End: 959477

Strand: Direct

Name: insK [H]

Synonym: NMCC_0958

Alternate gene names: 161869926

Gene position: 958728-959477 (Clockwise)

Preceding gene: 161869925

Following gene: 161869941

Centisome position: 44.52

GC content: 47.2

Gene sequence:

>750_bases
ATGCCATCCGTTGAACTGCTGTTGGAGATTGTCGGACTGCCACGCGGCACCTTCTATTACCAATTGGCCGTCCAATCGGC
AGAAGACAAATATGCCGATTTGAAACAGCATATCCATGATATTTATCGACGACATAAGGGAAGATACGGCTACCGGAGGA
TTGCAGCAGCCATCCTTCATGCAGGAACACCGGTCAATCACAAGAAAGTCAGCCGTCTGATGGCGAAGACGGGGCTGAAG
GCAGTGATACGGCGGCGCAAATACCGCTCGTTCAAAGGAGAAGTCGGCAAAATTGCGCCGAATATCCTGCGACGCTGTTT
CCATGCAGAAAAGCCGAATGAGAAATGGGTAACGGACGTTACCGAGTTCAATGTAGGCGGAGAAAAGATATACCTTTCTC
CGATTATGGATTTGTTTAACGGGGAAATCGTCAGTTACCGTATTCAAATCCGCCCGACTTTCGATTTGGCCGGCGAGATA
CTGAAAGGTGCGCCGGAGAAACCGGGATCGTCTGAAAAGCCGATACTGCATTCGGATCAAGGTTGGCAATATCAGATGTT
TTTTTATAGTGGATTAAATTTAAATCAGGACAAGGCGATGAAGCCGCAGACAGTACAAATAGTACGGCAAGGCGAGGCAA
CGCCGTACTGGTTTAAATTTAATCCACTATACAACAACGATAGAATCAAGTTGAAATTAAAAGGGCTGAGCCTTGTTCAG
TACAGAATTCAGTCCCTGAAAGCCGCTTGA

Upstream 100 bases:

>100_bases
TGCCTTACAGCGGAAATGGCTGCCCTAAAAAAGCCCGATGCCTTAATCCATGGGAAAGAAGTGCGGCAGAAAGAACGCAA
CTCGTCGCAGGGTTAAGGCA

Downstream 100 bases:

>100_bases
TTAAACTGTCCGACTTTTTGGGGTCAGTTCGGCTTCGGCATTTTTTTATCCGTTTGGGGGTAACTTGTTTGGAAAGCTGC
AAGCTTATAAATAAAGGATT

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MPSVELLLEIVGLPRGTFYYQLAVQSAEDKYADLKQHIHDIYRRHKGRYGYRRIAAAILHAGTPVNHKKVSRLMAKTGLK
AVIRRRKYRSFKGEVGKIAPNILRRCFHAEKPNEKWVTDVTEFNVGGEKIYLSPIMDLFNGEIVSYRIQIRPTFDLAGEI
LKGAPEKPGSSEKPILHSDQGWQYQMFFYSGLNLNQDKAMKPQTVQIVRQGEATPYWFKFNPLYNNDRIKLKLKGLSLVQ
YRIQSLKAA

Sequences:

>Translated_249_residues
MPSVELLLEIVGLPRGTFYYQLAVQSAEDKYADLKQHIHDIYRRHKGRYGYRRIAAAILHAGTPVNHKKVSRLMAKTGLK
AVIRRRKYRSFKGEVGKIAPNILRRCFHAEKPNEKWVTDVTEFNVGGEKIYLSPIMDLFNGEIVSYRIQIRPTFDLAGEI
LKGAPEKPGSSEKPILHSDQGWQYQMFFYSGLNLNQDKAMKPQTVQIVRQGEATPYWFKFNPLYNNDRIKLKLKGLSLVQ
YRIQSLKAA
>Mature_248_residues
PSVELLLEIVGLPRGTFYYQLAVQSAEDKYADLKQHIHDIYRRHKGRYGYRRIAAAILHAGTPVNHKKVSRLMAKTGLKA
VIRRRKYRSFKGEVGKIAPNILRRCFHAEKPNEKWVTDVTEFNVGGEKIYLSPIMDLFNGEIVSYRIQIRPTFDLAGEIL
KGAPEKPGSSEKPILHSDQGWQYQMFFYSGLNLNQDKAMKPQTVQIVRQGEATPYWFKFNPLYNNDRIKLKLKGLSLVQY
RIQSLKAA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=197, Percent_Identity=27.4111675126904, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1789981, Length=266, Percent_Identity=42.4812030075188, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1788405, Length=187, Percent_Identity=25.1336898395722, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787263, Length=187, Percent_Identity=25.1336898395722, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786753, Length=187, Percent_Identity=25.1336898395722, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786570, Length=187, Percent_Identity=25.1336898395722, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786490, Length=187, Percent_Identity=25.1336898395722, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 28712; Mature: 28581

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVELLLEIVGLPRGTFYYQLAVQSAEDKYADLKQHIHDIYRRHKGRYGYRRIAAAILH
CCHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AGTPVNHKKVSRLMAKTGLKAVIRRRKYRSFKGEVGKIAPNILRRCFHAEKPNEKWVTDV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
TEFNVGGEKIYLSPIMDLFNGEIVSYRIQIRPTFDLAGEILKGAPEKPGSSEKPILHSDQ
HHCCCCCCEEEHHHHHHHHCCCEEEEEEEEEECHHHHHHHHCCCCCCCCCCCCCEEECCC
GWQYQMFFYSGLNLNQDKAMKPQTVQIVRQGEATPYWFKFNPLYNNDRIKLKLKGLSLVQ
CCEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCHHHHH
YRIQSLKAA
HHHHHHCCC
>Mature Secondary Structure 
PSVELLLEIVGLPRGTFYYQLAVQSAEDKYADLKQHIHDIYRRHKGRYGYRRIAAAILH
CHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AGTPVNHKKVSRLMAKTGLKAVIRRRKYRSFKGEVGKIAPNILRRCFHAEKPNEKWVTDV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
TEFNVGGEKIYLSPIMDLFNGEIVSYRIQIRPTFDLAGEILKGAPEKPGSSEKPILHSDQ
HHCCCCCCEEEHHHHHHHHCCCEEEEEEEEEECHHHHHHHHCCCCCCCCCCCCCEEECCC
GWQYQMFFYSGLNLNQDKAMKPQTVQIVRQGEATPYWFKFNPLYNNDRIKLKLKGLSLVQ
CCEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCHHHHH
YRIQSLKAA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]