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The map label for this gene is mdaB [H]

Identifier: 161869889

GI number: 161869889

Start: 923003

End: 923563

Strand: Direct

Name: mdaB [H]

Synonym: NMCC_0920

Alternate gene names: 161869889

Gene position: 923003-923563 (Clockwise)

Preceding gene: 161869888

Following gene: 161869893

Centisome position: 42.86

GC content: 48.13

Gene sequence:

>561_bases
GTGGGAATCCAGGACGAAAAATCTCTAGAAACCGTTTTACCCGATAAGTTTCCGCACCGACAGGTCTGGATTCCCGCATG
CGCGGGAATGACGATGCAGGTATTTCTGACGATTCCCGGCTATGATGTTGAGGCAGAAATCGAAAAATTCGTTTGGATGG
ATGCTGTGATTTGGCAGATGCCGAGCTGGTGGATGCACGAGCCTTGGACAGTGAAAAAATACATAGACGAAGTATTAACC
GCTGGACACGGCAAACTCTACCAAAGCGACGGCAGACACAGCGTCAATCCGACTGAGGGCTACGGCACAGGCGGCTTGTT
GCAAGGCAAAAAACATATGCTTTCACTGACTTGGAATGCGCCGATTGAGGCGTTTACCCGCGAAGGCGATTTCTTTGAAG
GCAAAGGCGTTGATGTTTTGTATATGCACTTCCACAAAGCCAACGAGTTTTTGGGTATGACCCGCCTGCCGACATTCTTA
TGTAACGATGTGGTTAAAAATCCGCAAGTGGAAAAATACTTGGCAGATTATCAGGCACACTTGGAAAAAGTGTTCGGCTA
A

Upstream 100 bases:

>100_bases
ATGAATTGGATTCCCGCCTGCGCGGGAATGACGAATCCATCCGTACGGAAACCTGCACCACGTCATTCCCACGAACCTAC
ATTCCGTCATTCCCACGAAA

Downstream 100 bases:

>100_bases
TTAAAAATCCATCTTCAACACGGAGATGGATTTTGTTTGTTTCGTTGATTTTGTGTCAGTTTCAGATGTAGGTGCTTATT
CGGACGGGCCGTCTGAAAAT

Product: modulator of drug activity B, putative

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MGIQDEKSLETVLPDKFPHRQVWIPACAGMTMQVFLTIPGYDVEAEIEKFVWMDAVIWQMPSWWMHEPWTVKKYIDEVLT
AGHGKLYQSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMTRLPTFL
CNDVVKNPQVEKYLADYQAHLEKVFG

Sequences:

>Translated_186_residues
MGIQDEKSLETVLPDKFPHRQVWIPACAGMTMQVFLTIPGYDVEAEIEKFVWMDAVIWQMPSWWMHEPWTVKKYIDEVLT
AGHGKLYQSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMTRLPTFL
CNDVVKNPQVEKYLADYQAHLEKVFG
>Mature_185_residues
GIQDEKSLETVLPDKFPHRQVWIPACAGMTMQVFLTIPGYDVEAEIEKFVWMDAVIWQMPSWWMHEPWTVKKYIDEVLTA
GHGKLYQSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMTRLPTFLC
NDVVKNPQVEKYLADYQAHLEKVFG

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli madB and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=158, Percent_Identity=58.8607594936709, Blast_Score=207, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 21384; Mature: 21253

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIQDEKSLETVLPDKFPHRQVWIPACAGMTMQVFLTIPGYDVEAEIEKFVWMDAVIWQM
CCCCCCCHHHHHCCCCCCCCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHC
PSWWMHEPWTVKKYIDEVLTAGHGKLYQSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNA
CCCCCCCCEEHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCEECCCCEEEEEEECC
PIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMTRLPTFLCNDVVKNPQVEKYLADYQAH
CHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LEKVFG
HHHHCC
>Mature Secondary Structure 
GIQDEKSLETVLPDKFPHRQVWIPACAGMTMQVFLTIPGYDVEAEIEKFVWMDAVIWQM
CCCCCCHHHHHCCCCCCCCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHC
PSWWMHEPWTVKKYIDEVLTAGHGKLYQSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNA
CCCCCCCCEEHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCEECCCCEEEEEEECC
PIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMTRLPTFLCNDVVKNPQVEKYLADYQAH
CHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LEKVFG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]