| Definition | Neisseria meningitidis 053442, complete genome. |
|---|---|
| Accession | NC_010120 |
| Length | 2,153,416 |
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The map label for this gene is uvrA [H]
Identifier: 161869875
GI number: 161869875
Start: 909558
End: 912332
Strand: Reverse
Name: uvrA [H]
Synonym: NMCC_0906
Alternate gene names: 161869875
Gene position: 912332-909558 (Counterclockwise)
Preceding gene: 161869877
Following gene: 161869874
Centisome position: 42.37
GC content: 56.97
Gene sequence:
>2775_bases TTGAAAAACGTCGATTTGGACATTCCGCGCCACAAGCTCGTGGTGGTAACAGGATTGTCGGGCAGCGGCAAATCGTCGCT AGCGTTTGATACTTTATATGCCGAAGGCCAACGCCGTTATGTCGAGAGCCTGTCCGCCTATGCGCGGCAGTTTTTGCAGA TGATGGACAAACCCGATGTCGATTTGATCGAAGGCCTGTCGCCCGCGATTTCCATCGAGCAGAAATCCACCAGCCACAAT CCGCGTTCCACCGTCGGCACGGTTACGGAAATCCACGACTATCTGCGCCTTTTGTACGCACGCGTCGGCACACCCTACTG CCCCGAACACAAGCTGCCGCTATCCAGCCAAACCGTATCTCAAATGGTTGATGCCGTCTTAAAACTGCCGGAAGACACGC GCGTGATGATTCTGGCGCCGGCGGTACGAGAGCGTAAGGGCGAGTTTGTCGATTTCTTTGCCGACTTGCAGGCGCAGGGT TTTGCGCGCGTGCGCGTGGACGGCGAAGTCTATCAGTTGGACGAAGTGCCGAAGCTGGAAAAAAACATCAAGCACAATAT CGACGTGGTCATCGACCGTGTAAAAGTGAAGGCGGACATCAAGCAGCGGCTGGCGGAAAGTTTTGAAACCGCGTTACGCC ACGGCAACGAGCGCGCGCTGGCGATGGAGATGGACAGCGGCGAAGAACATTGGTTTTCCGCGCGTTTCGCCTGCCCCGTA TGTTCGTACAGCCTGCCAGAATTAGAGCCGCGCCTGTTTTCCTTCAACAACCCGATGGGTTCCTGCCCGACTTGCGACGG CTTGGGCAACACCAATTTCTTCGACCCCGAAAAAGTGGTCGCCCACCCCGAATTGTCGCTGGCTTCGGGCGCGATTGACG GCTGGGACAAACGCAACCAGTTCTATTTCCAAATGATTCAGTCGCTGGCACGGCATTACGGTTTTGATGTGCAGGCTGCT TGGGAAACCCTACCTGCAAAAATCAAAAAAGTCGTGTTGCACGGTTCGGGCAAGGAAGTCATTGATTTCACCTACCTATC CGAACGCGGCACCACCTTCAACCGCAGCCACGCCTTCGAAGGCATCATTCCCAATCTCGAACGCCGCTACCGCGAAACCG ACAGCGAAACCGTGCGCGAAAAATTGCGCGAATACCAAAACCACCGCGCCTGCCCGAGCTGCGGCGGTGCACGTTTGCGC AAAGAAGCGCGCTACGTTTACGTCAGCGGCGAACCGTTGCACGAAGTCTCCGCCTGGCCGCTGACCAAAACCCACCAATT CTTTGAAACGCTGGATTTGGACGGCAACAAAAAACAAATCGCCGAAAAAATCCTCAAAGAAATCACCGAGCGGCTTGGCT TTTTGATTAACGTCGGGCTGGATTACCTGAATTTAAGCCGCTCCGCCGAAACCCTCTCCGGCGGCGAAGCCCAGCGTATC CGCCTCGCCAGCCAAATCGGCAGCGGCCTGACCGGCGTGATGTACGTTTTGGACGAACCCTCCATCGGCCTGCACCAGCG CGACAACGACCGCCTGCTCGCCACCCTCAAACGCCTGCGCGATTTAGGCAACAGCGTGATTGTAGTCGAACACGACGAAG ACGCCATCCGCGAAGCCGATTTCGTCGTCGATATGGGCCCGGGCGCAGGCGAACACGGCGGCAACGTATTGATTGCCGAC ACGCCCGAAAACGTCGCCAAATGTGAAAACTCCGTTACCGGACAATACCTCAGCGGCAAAAAATCCATTGCCGTGCCGTC TGAACGCACACCCGTCAATCCCGACCGAATGCTCGTCCTCAAAGGCGCGCGCGGCAACAACCTCAAAAACGTTACCCTCG AACTGCCGCTCGGTTTGATTACCTGCATCACCGGCGTATCCGGCAGCGGCAAGTCCACCCTGATTAACGACACCCTCGCC AAAATCACCGCCCGCGAACTCAACCGCGCCCAAGAAGAACCCGCCCCATACGACGACATCCGCGGCCTCGAACACCTCGA CAAAGTCATCAACGTCGACCAATCCCCCATCGGCCGCACCCCACGCTCCAATCCCGCCACCTACACCGGCCTGTTCACCC CCATCCGCGAACTCTTCGCCGGCGTACCCCTCTCGCGCGAACGCGGCTACAATGTCGGCAGATTCTCCTTCAACGTCAAA GGCGGCCGCTGCGAAGCCTGCCAAGGCGACGGCGTCATCAAAGTCGAAATGCACTTCCTGCCCGACGTGTATGTTCCCTG CGAAGTCTGCCACGGCAAACGCTACAACCGCGAAACGCTCGAAATCCAATACAAAGGCAAAAACATCAGCCAAGTCCTCG ACATGACCGTTGAAGAAGCCCGCGAATTTTTCGACGCCGTCCCCACCGTATCGCGCAAACTGCAAACCCTGATGGACGTA GGCCTCGGCTACATCCGCCTCGGCCAATCCGCCACCACCCTCTCCGGCGGCGAAGCCCAGCGCGTCAAACTCGCCTTGGA ACTCTCCAAACGCGACACCGGCAGAACGCTCTATATCCTCGACGAACCCACCACCGGCCTGCACTTCGCCGACATCGCCC TGCTGCTGGAAGTCATAGGTCGTCTGAAAGGCAAAGGCAACTCGATAGTGATTATCGAGCATAATCTGGATGTGATTAAA ACCGCCGATTGGATTGTGGACTTAGGGCCAGAAGGCGGCGACGGCGGAGGGAGGATTATTGCTTCAGGTAGCCCGGAGGA AGTGGCGAAGGTTAAGGGGAGTTATACTGGGAAGTATTTGAAGAATATACTTTAA
Upstream 100 bases:
>100_bases TTCCTTTATTTTTCAGGCGGCATCCATTATGTGCAACCATCATCCCAAACATTCGCACGGCAACGACACCATCCGCATCC GCGGCGCGCGCACGCATAAT
Downstream 100 bases:
>100_bases AAAACGGGATGGTTTAAACCATCCCGTTTTTTATTCCTTCTGTTTTCGATTTTGTTTGGCTTTGAAGCTATCAAAAATAA TGCTAAATCCCAAACAGGTG
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 924; Mature: 924
Protein sequence:
>924_residues MKNVDLDIPRHKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMDKPDVDLIEGLSPAISIEQKSTSHN PRSTVGTVTEIHDYLRLLYARVGTPYCPEHKLPLSSQTVSQMVDAVLKLPEDTRVMILAPAVRERKGEFVDFFADLQAQG FARVRVDGEVYQLDEVPKLEKNIKHNIDVVIDRVKVKADIKQRLAESFETALRHGNERALAMEMDSGEEHWFSARFACPV CSYSLPELEPRLFSFNNPMGSCPTCDGLGNTNFFDPEKVVAHPELSLASGAIDGWDKRNQFYFQMIQSLARHYGFDVQAA WETLPAKIKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFEGIIPNLERRYRETDSETVREKLREYQNHRACPSCGGARLR KEARYVYVSGEPLHEVSAWPLTKTHQFFETLDLDGNKKQIAEKILKEITERLGFLINVGLDYLNLSRSAETLSGGEAQRI RLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAIREADFVVDMGPGAGEHGGNVLIAD TPENVAKCENSVTGQYLSGKKSIAVPSERTPVNPDRMLVLKGARGNNLKNVTLELPLGLITCITGVSGSGKSTLINDTLA KITARELNRAQEEPAPYDDIRGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPLSRERGYNVGRFSFNVK GGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMTVEEAREFFDAVPTVSRKLQTLMDV GLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADIALLLEVIGRLKGKGNSIVIIEHNLDVIK TADWIVDLGPEGGDGGGRIIASGSPEEVAKVKGSYTGKYLKNIL
Sequences:
>Translated_924_residues MKNVDLDIPRHKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMDKPDVDLIEGLSPAISIEQKSTSHN PRSTVGTVTEIHDYLRLLYARVGTPYCPEHKLPLSSQTVSQMVDAVLKLPEDTRVMILAPAVRERKGEFVDFFADLQAQG FARVRVDGEVYQLDEVPKLEKNIKHNIDVVIDRVKVKADIKQRLAESFETALRHGNERALAMEMDSGEEHWFSARFACPV CSYSLPELEPRLFSFNNPMGSCPTCDGLGNTNFFDPEKVVAHPELSLASGAIDGWDKRNQFYFQMIQSLARHYGFDVQAA WETLPAKIKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFEGIIPNLERRYRETDSETVREKLREYQNHRACPSCGGARLR KEARYVYVSGEPLHEVSAWPLTKTHQFFETLDLDGNKKQIAEKILKEITERLGFLINVGLDYLNLSRSAETLSGGEAQRI RLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAIREADFVVDMGPGAGEHGGNVLIAD TPENVAKCENSVTGQYLSGKKSIAVPSERTPVNPDRMLVLKGARGNNLKNVTLELPLGLITCITGVSGSGKSTLINDTLA KITARELNRAQEEPAPYDDIRGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPLSRERGYNVGRFSFNVK GGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMTVEEAREFFDAVPTVSRKLQTLMDV GLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADIALLLEVIGRLKGKGNSIVIIEHNLDVIK TADWIVDLGPEGGDGGGRIIASGSPEEVAKVKGSYTGKYLKNIL >Mature_924_residues MKNVDLDIPRHKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMDKPDVDLIEGLSPAISIEQKSTSHN PRSTVGTVTEIHDYLRLLYARVGTPYCPEHKLPLSSQTVSQMVDAVLKLPEDTRVMILAPAVRERKGEFVDFFADLQAQG FARVRVDGEVYQLDEVPKLEKNIKHNIDVVIDRVKVKADIKQRLAESFETALRHGNERALAMEMDSGEEHWFSARFACPV CSYSLPELEPRLFSFNNPMGSCPTCDGLGNTNFFDPEKVVAHPELSLASGAIDGWDKRNQFYFQMIQSLARHYGFDVQAA WETLPAKIKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFEGIIPNLERRYRETDSETVREKLREYQNHRACPSCGGARLR KEARYVYVSGEPLHEVSAWPLTKTHQFFETLDLDGNKKQIAEKILKEITERLGFLINVGLDYLNLSRSAETLSGGEAQRI RLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAIREADFVVDMGPGAGEHGGNVLIAD TPENVAKCENSVTGQYLSGKKSIAVPSERTPVNPDRMLVLKGARGNNLKNVTLELPLGLITCITGVSGSGKSTLINDTLA KITARELNRAQEEPAPYDDIRGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPLSRERGYNVGRFSFNVK GGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMTVEEAREFFDAVPTVSRKLQTLMDV GLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADIALLLEVIGRLKGKGNSIVIIEHNLDVIK TADWIVDLGPEGGDGGGRIIASGSPEEVAKVKGSYTGKYLKNIL
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=927, Percent_Identity=70.1186623516721, Blast_Score=1326, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 102492; Mature: 102492
Theoretical pI: Translated: 6.52; Mature: 6.52
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNVDLDIPRHKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMDKPDV CCCCCCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH DLIEGLSPAISIEQKSTSHNPRSTVGTVTEIHDYLRLLYARVGTPYCPEHKLPLSSQTVS HHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH QMVDAVLKLPEDTRVMILAPAVRERKGEFVDFFADLQAQGFARVRVDGEVYQLDEVPKLE HHHHHHHHCCCCCEEEEEECHHHHHCCCHHHHHHHHCCCCEEEEEECCCEEECCCCCHHH KNIKHNIDVVIDRVKVKADIKQRLAESFETALRHGNERALAMEMDSGEEHWFSARFACPV HHHCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCH CSYSLPELEPRLFSFNNPMGSCPTCDGLGNTNFFDPEKVVAHPELSLASGAIDGWDKRNQ HCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHCCCCCCCCCCHH FYFQMIQSLARHYGFDVQAAWETLPAKIKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFE HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCEEEEEEECCCCCCCCCCCCCC GIIPNLERRYRETDSETVREKLREYQNHRACPSCGGARLRKEARYVYVSGEPLHEVSAWP CCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEECCCCCHHCCCCC LTKTHQFFETLDLDGNKKQIAEKILKEITERLGFLINVGLDYLNLSRSAETLSGGEAQRI CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCEEEECCHHHHHCCCCHHHCCCCCHHHH RLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAIREAD HHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHCCC FVVDMGPGAGEHGGNVLIADTPENVAKCENSVTGQYLSGKKSIAVPSERTPVNPDRMLVL EEEECCCCCCCCCCEEEEECCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCEEEE KGARGNNLKNVTLELPLGLITCITGVSGSGKSTLINDTLAKITARELNRAQEEPAPYDDI ECCCCCCCCEEEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH RGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPLSRERGYNVGRFSFNVK HHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCHHCCCCEEEEEEEEC GGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMTVEEA CCEECCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHH REFFDAVPTVSRKLQTLMDVGLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYIL HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEE DEPTTGLHFADIALLLEVIGRLKGKGNSIVIIEHNLDVIKTADWIVDLGPEGGDGGGRII ECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCEEEEECCCCCCCCCEEE ASGSPEEVAKVKGSYTGKYLKNIL ECCCHHHHHHHCCCCCHHHHHHCC >Mature Secondary Structure MKNVDLDIPRHKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMDKPDV CCCCCCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH DLIEGLSPAISIEQKSTSHNPRSTVGTVTEIHDYLRLLYARVGTPYCPEHKLPLSSQTVS HHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH QMVDAVLKLPEDTRVMILAPAVRERKGEFVDFFADLQAQGFARVRVDGEVYQLDEVPKLE HHHHHHHHCCCCCEEEEEECHHHHHCCCHHHHHHHHCCCCEEEEEECCCEEECCCCCHHH KNIKHNIDVVIDRVKVKADIKQRLAESFETALRHGNERALAMEMDSGEEHWFSARFACPV HHHCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCH CSYSLPELEPRLFSFNNPMGSCPTCDGLGNTNFFDPEKVVAHPELSLASGAIDGWDKRNQ HCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHCCCCCCCCCCHH FYFQMIQSLARHYGFDVQAAWETLPAKIKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFE HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCEEEEEEECCCCCCCCCCCCCC GIIPNLERRYRETDSETVREKLREYQNHRACPSCGGARLRKEARYVYVSGEPLHEVSAWP CCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEECCCCCHHCCCCC LTKTHQFFETLDLDGNKKQIAEKILKEITERLGFLINVGLDYLNLSRSAETLSGGEAQRI CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCEEEECCHHHHHCCCCHHHCCCCCHHHH RLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAIREAD HHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHCCC FVVDMGPGAGEHGGNVLIADTPENVAKCENSVTGQYLSGKKSIAVPSERTPVNPDRMLVL EEEECCCCCCCCCCEEEEECCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCEEEE KGARGNNLKNVTLELPLGLITCITGVSGSGKSTLINDTLAKITARELNRAQEEPAPYDDI ECCCCCCCCEEEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH RGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPLSRERGYNVGRFSFNVK HHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCHHCCCCEEEEEEEEC GGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMTVEEA CCEECCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHH REFFDAVPTVSRKLQTLMDVGLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYIL HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCEEEEE DEPTTGLHFADIALLLEVIGRLKGKGNSIVIIEHNLDVIKTADWIVDLGPEGGDGGGRII ECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCEEEEECCCCCCCCCEEE ASGSPEEVAKVKGSYTGKYLKNIL ECCCHHHHHHHCCCCCHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9197406 [H]