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The map label for this gene is hisS [H]

Identifier: 161869789

GI number: 161869789

Start: 823732

End: 825027

Strand: Reverse

Name: hisS [H]

Synonym: NMCC_0812

Alternate gene names: 161869789

Gene position: 825027-823732 (Counterclockwise)

Preceding gene: 161869790

Following gene: 161869788

Centisome position: 38.31

GC content: 51.39

Gene sequence:

>1296_bases
ATGGCACAAAAAATCCAATCCGTCAAAGGCATGAACGACCTTCTGCCTGTCGAGCAAAAAGATTTCAAACTGACGGCTGC
GTTTTGGCAGGCGTTTGAAGATACGGTCGGCCGCTGGACACGCACTTACGGTTATCAGCAAATCCGTACGCCGATTGTCG
AGCAAACCGGTTTGTTTGTCCGCTCCATCGGCGAGGAAACCGATGTGGTCGGCAAGGAAATGTACACCTTCTCCGATTCA
AACGATTCTTTGAGTTTGAGCTTGCGTCCTGAAGGTACGGCTTCCTGCCTGCGTGCGGTGGTCGAACACAACCTTCTCTA
CAACAGCCCGCAAAAGCTGTGGTATATGGGGCCGATGTTCCGCCGCGAGCGTCCGCAAAAAGGCCGTTATCGTCAGTTCC
ATCAGGTCGGTATCGAAGCTTTGGGTTTTGAAGGTCCGGATATTGATGCGGAAATCATCGCGATGTCTGCCGACTTGTGG
GAAAAATTGGGTATTCGCGAATACCTGACTTTGGAAATCAACAGCTTGGGCAACCGTGAGGAACGCGCGGCACACCGTGC
GGCATTGGTTGAATATCTGACCCGTTATGAAGATAAATTGGATGAAGACAGCAAACGCCGTCTGAAAACCAATCCTTTGC
GCGTTTTAGATACGAAAAACCCTGATTTGCAGGAAATCTGCAATGCCGCGCCGCGTTTGGTGGATTACTTGGGCGAGGCT
TCGCAAAACCACTATGCACGCTTCAAGGCGATGTTGGATGGTTTGGGTATTCAATATATTGAAAATCCGCGCTTGGTTCG
CGGTTTGGATTATTACAATCAGACGGTTTTTGAGTGGACGACCGACAAACTCGGCGCGCAGGCGACTGTGTGTGGCGGCG
GCCGTTACGATGGTTTGATTGAAGAACTTGGCGGCAAACCTGCGCCGTCTATCGGCTTTGCAATGGGCATCGAACGGTTG
CTGTTTTTGGTGAGCGAATACGGCTCGCTGGAAGTGAATGCTGCGCCTGATGTCTATGCAATGCACCAAGGCGAAAGGGC
GGACTTGCAAGTGATGAAATACGCGCAAGCCTTGCGCACACAAGGTTTCAATGTAATGCAGCATTCCGGCTATCAAAGCC
TGAAAGCGCAAATGAAAAAAGCCGACAACAGCGGCGCGCGCTTTGCCCTGATTGTCGCGCAAGACGAACTGGCGAACGGT
ACGGTTACGCTCAAAGATATGAACGGCGCACACGGTCAGCAAACTGTCGCCGCCGCTGATTTGACAAACACTTTACAACA
ATGGAAGAACGCATAA

Upstream 100 bases:

>100_bases
AGAGTAAGTCAAATGCCGTCCGCAAACCACCCCCAACCTCACAAACCCTTAAAAATCCGCTATAATCGCCCGCAATTTGA
TTTAAGCATTCTTACTTGAA

Downstream 100 bases:

>100_bases
ATGGCAGCCCATTTGGAAGAACAACAAGAGTTGGACAACTTTAAATATTTTTGGAAAACCACGGGCAAATGGCTGTTTGC
CCTGCTGATTTTGGCGGCGC

Product: histidyl-tRNA synthetase

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MAQKIQSVKGMNDLLPVEQKDFKLTAAFWQAFEDTVGRWTRTYGYQQIRTPIVEQTGLFVRSIGEETDVVGKEMYTFSDS
NDSLSLSLRPEGTASCLRAVVEHNLLYNSPQKLWYMGPMFRRERPQKGRYRQFHQVGIEALGFEGPDIDAEIIAMSADLW
EKLGIREYLTLEINSLGNREERAAHRAALVEYLTRYEDKLDEDSKRRLKTNPLRVLDTKNPDLQEICNAAPRLVDYLGEA
SQNHYARFKAMLDGLGIQYIENPRLVRGLDYYNQTVFEWTTDKLGAQATVCGGGRYDGLIEELGGKPAPSIGFAMGIERL
LFLVSEYGSLEVNAAPDVYAMHQGERADLQVMKYAQALRTQGFNVMQHSGYQSLKAQMKKADNSGARFALIVAQDELANG
TVTLKDMNGAHGQQTVAAADLTNTLQQWKNA

Sequences:

>Translated_431_residues
MAQKIQSVKGMNDLLPVEQKDFKLTAAFWQAFEDTVGRWTRTYGYQQIRTPIVEQTGLFVRSIGEETDVVGKEMYTFSDS
NDSLSLSLRPEGTASCLRAVVEHNLLYNSPQKLWYMGPMFRRERPQKGRYRQFHQVGIEALGFEGPDIDAEIIAMSADLW
EKLGIREYLTLEINSLGNREERAAHRAALVEYLTRYEDKLDEDSKRRLKTNPLRVLDTKNPDLQEICNAAPRLVDYLGEA
SQNHYARFKAMLDGLGIQYIENPRLVRGLDYYNQTVFEWTTDKLGAQATVCGGGRYDGLIEELGGKPAPSIGFAMGIERL
LFLVSEYGSLEVNAAPDVYAMHQGERADLQVMKYAQALRTQGFNVMQHSGYQSLKAQMKKADNSGARFALIVAQDELANG
TVTLKDMNGAHGQQTVAAADLTNTLQQWKNA
>Mature_430_residues
AQKIQSVKGMNDLLPVEQKDFKLTAAFWQAFEDTVGRWTRTYGYQQIRTPIVEQTGLFVRSIGEETDVVGKEMYTFSDSN
DSLSLSLRPEGTASCLRAVVEHNLLYNSPQKLWYMGPMFRRERPQKGRYRQFHQVGIEALGFEGPDIDAEIIAMSADLWE
KLGIREYLTLEINSLGNREERAAHRAALVEYLTRYEDKLDEDSKRRLKTNPLRVLDTKNPDLQEICNAAPRLVDYLGEAS
QNHYARFKAMLDGLGIQYIENPRLVRGLDYYNQTVFEWTTDKLGAQATVCGGGRYDGLIEELGGKPAPSIGFAMGIERLL
FLVSEYGSLEVNAAPDVYAMHQGERADLQVMKYAQALRTQGFNVMQHSGYQSLKAQMKKADNSGARFALIVAQDELANGT
VTLKDMNGAHGQQTVAAADLTNTLQQWKNA

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1788861, Length=424, Percent_Identity=54.0094339622642, Blast_Score=457, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.21 [H]

Molecular weight: Translated: 48547; Mature: 48415

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKIQSVKGMNDLLPVEQKDFKLTAAFWQAFEDTVGRWTRTYGYQQIRTPIVEQTGLFV
CCCHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RSIGEETDVVGKEMYTFSDSNDSLSLSLRPEGTASCLRAVVEHNLLYNSPQKLWYMGPMF
HHCCCHHHHHHHHHEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEECCCHH
RRERPQKGRYRQFHQVGIEALGFEGPDIDAEIIAMSADLWEKLGIREYLTLEINSLGNRE
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHEEECHHHHHHCCCCEEEEEEECCCCCHH
ERAAHRAALVEYLTRYEDKLDEDSKRRLKTNPLRVLDTKNPDLQEICNAAPRLVDYLGEA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC
SQNHYARFKAMLDGLGIQYIENPRLVRGLDYYNQTVFEWTTDKLGAQATVCGGGRYDGLI
CCHHHHHHHHHHHCCCCEEECCCCCEEHHHHHCCHHEEECHHHCCCEEEEECCCCHHHHH
EELGGKPAPSIGFAMGIERLLFLVSEYGSLEVNAAPDVYAMHQGERADLQVMKYAQALRT
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHH
QGFNVMQHSGYQSLKAQMKKADNSGARFALIVAQDELANGTVTLKDMNGAHGQQTVAAAD
CCCHHHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHH
LTNTLQQWKNA
HHHHHHHHCCC
>Mature Secondary Structure 
AQKIQSVKGMNDLLPVEQKDFKLTAAFWQAFEDTVGRWTRTYGYQQIRTPIVEQTGLFV
CCHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RSIGEETDVVGKEMYTFSDSNDSLSLSLRPEGTASCLRAVVEHNLLYNSPQKLWYMGPMF
HHCCCHHHHHHHHHEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEECCCHH
RRERPQKGRYRQFHQVGIEALGFEGPDIDAEIIAMSADLWEKLGIREYLTLEINSLGNRE
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHEEECHHHHHHCCCCEEEEEEECCCCCHH
ERAAHRAALVEYLTRYEDKLDEDSKRRLKTNPLRVLDTKNPDLQEICNAAPRLVDYLGEA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC
SQNHYARFKAMLDGLGIQYIENPRLVRGLDYYNQTVFEWTTDKLGAQATVCGGGRYDGLI
CCHHHHHHHHHHHCCCCEEECCCCCEEHHHHHCCHHEEECHHHCCCEEEEECCCCHHHHH
EELGGKPAPSIGFAMGIERLLFLVSEYGSLEVNAAPDVYAMHQGERADLQVMKYAQALRT
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCCCCHHHHHHHHHHHHHH
QGFNVMQHSGYQSLKAQMKKADNSGARFALIVAQDELANGTVTLKDMNGAHGQQTVAAAD
CCCHHHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHH
LTNTLQQWKNA
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA