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The map label for this gene is drg [H]

Identifier: 161869319

GI number: 161869319

Start: 331363

End: 332241

Strand: Direct

Name: drg [H]

Synonym: NMCC_0324

Alternate gene names: 161869319

Gene position: 331363-332241 (Clockwise)

Preceding gene: 161869318

Following gene: 161869320

Centisome position: 15.39

GC content: 42.09

Gene sequence:

>879_bases
TTGCCCCGCCTTGCCCTGCTGTCTGCGGCTTCGTCTCTTTGTCCTGATTTTGTTAATCCACTAAAACTTAATCTCAAAAT
CCAAAACATGAATTTATTTTTCGATACTGAATTGGGGAAGCAACAAAATAAAGCAACCCACAAAATCCGTGTAATGAGCG
AGGCTTGGTTGGAAAAAAACGGCTACTGCCCCTGTTGCGGAAGCAAGCCGATGAAGAGATTTGCCAATAACAAACCTGTT
GCAGACCTCTTTTGCCCAAATTGCCACGAGCAATATGAATTAAAGAGTAAAAATCAAAAAACCATAGGCAACATCGTGCC
TGACGGTGCATATCACACCATGTTGGAGCGCATCCGGTCAGATACCAACCCCAACTTTTTCTTTCTTGCATATAAAAAAG
CGGATTACTCCATACGGCAATTGGTGCTTGTACCCAAACATTTCATCACGCCGGATATGATTATTCCCAGAAATAAAGGC
ATTAAAAACCGGCCGCACCACATTATGTGTTCCATCAATCTCGCCCCTTTGCCTGAAAGCGGAAAAATATTCTTAATAGA
CGATTCCCGCATTATCGAACCCGAAACCGTTCTGAAAAAATGGCAATCTAATCTGTTTTTACGCAACCAAAATGCGGAGC
GCAAAGGTTGGCTTTTGGCTGTTATGAAATGTATCGACCAACTCCCCGAAGAATTCACATTGTCGCAAATGTATGAATTT
GAAAACAAACTATCCATCCAATTTCCCCAAAACAACCATATCAAAGACAAAATCCGCCAACAGTTGCAAATTTTGCGCGA
CCAAAATACGATCGAATTCATTGGTCGCGGACTTTACAAAAAAATCGACAAATTGCGTCCGACTTCCAAGGCGGTTTGA

Upstream 100 bases:

>100_bases
AAACTTGGAAACAGGGTTTCAGACGGCCTTTTTAAGGCAGATTGGGTTGTCCGCATGACAGACCTCAAATATAGTGGATT
AACTTTAAACCGGTACGGCG

Downstream 100 bases:

>100_bases
TTTCAAATCATGATACTGAATTCACAAGGGATATTTATTCCTTTGCTATTCTGAAAACAGTTGAAGTTCAGCGCAATATT
GCCGAAAAAGGCAGCAGCCG

Product: type II restriction endonuclease

Products: NA

Alternate protein names: R.DpnI; Endonuclease DpnI; Type II restriction enzyme DpnI [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MPRLALLSAASSLCPDFVNPLKLNLKIQNMNLFFDTELGKQQNKATHKIRVMSEAWLEKNGYCPCCGSKPMKRFANNKPV
ADLFCPNCHEQYELKSKNQKTIGNIVPDGAYHTMLERIRSDTNPNFFFLAYKKADYSIRQLVLVPKHFITPDMIIPRNKG
IKNRPHHIMCSINLAPLPESGKIFLIDDSRIIEPETVLKKWQSNLFLRNQNAERKGWLLAVMKCIDQLPEEFTLSQMYEF
ENKLSIQFPQNNHIKDKIRQQLQILRDQNTIEFIGRGLYKKIDKLRPTSKAV

Sequences:

>Translated_292_residues
MPRLALLSAASSLCPDFVNPLKLNLKIQNMNLFFDTELGKQQNKATHKIRVMSEAWLEKNGYCPCCGSKPMKRFANNKPV
ADLFCPNCHEQYELKSKNQKTIGNIVPDGAYHTMLERIRSDTNPNFFFLAYKKADYSIRQLVLVPKHFITPDMIIPRNKG
IKNRPHHIMCSINLAPLPESGKIFLIDDSRIIEPETVLKKWQSNLFLRNQNAERKGWLLAVMKCIDQLPEEFTLSQMYEF
ENKLSIQFPQNNHIKDKIRQQLQILRDQNTIEFIGRGLYKKIDKLRPTSKAV
>Mature_291_residues
PRLALLSAASSLCPDFVNPLKLNLKIQNMNLFFDTELGKQQNKATHKIRVMSEAWLEKNGYCPCCGSKPMKRFANNKPVA
DLFCPNCHEQYELKSKNQKTIGNIVPDGAYHTMLERIRSDTNPNFFFLAYKKADYSIRQLVLVPKHFITPDMIIPRNKGI
KNRPHHIMCSINLAPLPESGKIFLIDDSRIIEPETVLKKWQSNLFLRNQNAERKGWLLAVMKCIDQLPEEFTLSQMYEFE
NKLSIQFPQNNHIKDKIRQQLQILRDQNTIEFIGRGLYKKIDKLRPTSKAV

Specific function: Recognizes the double-stranded and methylated sequence G(Me)ATC and cleaves after A-2 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010324 [H]

Pfam domain/function: PF06044 DRP [H]

EC number: =3.1.21.4 [H]

Molecular weight: Translated: 33904; Mature: 33773

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLALLSAASSLCPDFVNPLKLNLKIQNMNLFFDTELGKQQNKATHKIRVMSEAWLEKN
CCCHHHHHHHHHHCHHHCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCC
GYCPCCGSKPMKRFANNKPVADLFCPNCHEQYELKSKNQKTIGNIVPDGAYHTMLERIRS
CCCCCCCCCHHHHHCCCCCCHHHCCCCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHC
DTNPNFFFLAYKKADYSIRQLVLVPKHFITPDMIIPRNKGIKNRPHHIMCSINLAPLPES
CCCCCEEEEEEECCCCCCHHEEECCHHHCCCCEEECCCCCCCCCCCEEEEEEEECCCCCC
GKIFLIDDSRIIEPETVLKKWQSNLFLRNQNAERKGWLLAVMKCIDQLPEEFTLSQMYEF
CEEEEEECCCEECHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
ENKLSIQFPQNNHIKDKIRQQLQILRDQNTIEFIGRGLYKKIDKLRPTSKAV
CCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PRLALLSAASSLCPDFVNPLKLNLKIQNMNLFFDTELGKQQNKATHKIRVMSEAWLEKN
CCHHHHHHHHHHCHHHCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCC
GYCPCCGSKPMKRFANNKPVADLFCPNCHEQYELKSKNQKTIGNIVPDGAYHTMLERIRS
CCCCCCCCCHHHHHCCCCCCHHHCCCCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHC
DTNPNFFFLAYKKADYSIRQLVLVPKHFITPDMIIPRNKGIKNRPHHIMCSINLAPLPES
CCCCCEEEEEEECCCCCCHHEEECCHHHCCCCEEECCCCCCCCCCCEEEEEEEECCCCCC
GKIFLIDDSRIIEPETVLKKWQSNLFLRNQNAERKGWLLAVMKCIDQLPEEFTLSQMYEF
CEEEEEECCCEECHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
ENKLSIQFPQNNHIKDKIRQQLQILRDQNTIEFIGRGLYKKIDKLRPTSKAV
CCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2844782; 3019562; 11463916 [H]