Click here to switch to the map view.

The map label for this gene is resA [H]

Identifier: 161869252

GI number: 161869252

Start: 270946

End: 271434

Strand: Direct

Name: resA [H]

Synonym: NMCC_0257

Alternate gene names: 161869252

Gene position: 270946-271434 (Clockwise)

Preceding gene: 161869251

Following gene: 161869254

Centisome position: 12.58

GC content: 51.12

Gene sequence:

>489_bases
ATGAAAAAAATACTCACCGCCGCCGTCGTCGCACTGATCGGCATCCTCCTTGCCATCGTCCTCATCCCCGACAGCAAAAC
CGCGCCCGCCTTCTCCCTGCCCGACCTGCACGGAAAAACCGTTTCCAACGCCGACCTGCAAGGCAAAGTTACCCTGATTA
ATTTTTGGTTTCCCTCCTGTCCGGGTTGTGTGAGCGAAATGCCCAAAATCATTAAAACGGCAAATGACTATAAAAACAAA
AACTTCCAAGTACTTGCCGTCGCCCAGCCCATCGATCCGATAGAAAGCGTCCGCCAATATGTCAAAGACTACGGTTTGCC
GTTTACCGTCATGTATGATGCGGACAAAGCTGTCGGACAGGCGTTCGGCACACAGGTTTATCCGACTTCCGTCCTTATCG
GCAAAAAAGGCGAAATCCTCAAAACTTATGTCGGCGAACCCGATTTCGGCAAACTCTACCAAGAAATCGATACCGCGCTG
GCGCAATAG

Upstream 100 bases:

>100_bases
CCGCAGAAGCCGACATTACCCTGATGCCCGTCCACGCCGCCACACAACGCACCGTCAGCCTGCCCGCCACCCTTGCCCGC
GCATTGGAAGCCTTGTCCGA

Downstream 100 bases:

>100_bases
CGATGCCGTCTGAAGCGCAAAAAACAGAAACGATGTTCCTGTTTTTTCAGATCATCCGCCCCGACACGTTCAGACGGCAT
TCAACCTTTCGGCAGATTCT

Product: periplasmic protein

Products: Acceptor; H2O; oxidized thioredoxin [C]

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLPDLHGKTVSNADLQGKVTLINFWFPSCPGCVSEMPKIIKTANDYKNK
NFQVLAVAQPIDPIESVRQYVKDYGLPFTVMYDADKAVGQAFGTQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEIDTAL
AQ

Sequences:

>Translated_162_residues
MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLPDLHGKTVSNADLQGKVTLINFWFPSCPGCVSEMPKIIKTANDYKNK
NFQVLAVAQPIDPIESVRQYVKDYGLPFTVMYDADKAVGQAFGTQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEIDTAL
AQ
>Mature_162_residues
MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLPDLHGKTVSNADLQGKVTLINFWFPSCPGCVSEMPKIIKTANDYKNK
NFQVLAVAQPIDPIESVRQYVKDYGLPFTVMYDADKAVGQAFGTQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEIDTAL
AQ

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: 920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 17623; Mature: 17623

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLPDLHGKTVSNADLQGKVTLINFWFPSC
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCC
PGCVSEMPKIIKTANDYKNKNFQVLAVAQPIDPIESVRQYVKDYGLPFTVMYDADKAVGQ
CHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHHHHH
AFGTQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEIDTALAQ
HHCCCCCCCEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLPDLHGKTVSNADLQGKVTLINFWFPSC
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCC
PGCVSEMPKIIKTANDYKNKNFQVLAVAQPIDPIESVRQYVKDYGLPFTVMYDADKAVGQ
CHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHHHHH
AFGTQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEIDTALAQ
HHCCCCCCCEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced acceptor; H2O2; reduced thioredoxin [C]

Specific reaction: reduced acceptor + H2O2 = Acceptor + H2O reduced thioredoxin + H2O2 = oxidized thioredoxin + H2O [C]

General reaction: Oxidoreductases; Acting on a peroxide as acceptor; Peroxidase [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]