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The map label for this gene is map-2 [H]

Identifier: 161723130

GI number: 161723130

Start: 2297435

End: 2298250

Strand: Reverse

Name: map-2 [H]

Synonym: BTH_I2026

Alternate gene names: 161723130

Gene position: 2298250-2297435 (Counterclockwise)

Preceding gene: 83719699

Following gene: 83721536

Centisome position: 60.33

GC content: 64.46

Gene sequence:

>816_bases
ATGGCTATTACGCTCAAAAACGAACACGACATCGCGCAGATGCGCATCGCCTGCCGTCTCGCGAGCGAAGTGCTCGACTA
CATCACGCCGTTCGTCGTCGCCGGCGTGACGACGGGCGAACTCGACCGCCTCTGCCACGAGTACATGATCAATGTGCAGG
GTACGGTGCCCGCGCCGCTCAACTACCAGCCGCCGGGCTATCCGCCGTTCCCGAAGGCGATCTGCACTTCGGTCAACGAC
GTGATCTGCCACGGCATTCCGGGCGACAAGACGCTGAAGAACGGCGACGCGCTGAACATCGACATCACCGTCATCAAGAA
CGGCTATTTCGGCGACACGAGCCGGATGTTCCTCATCGGCGAGGGCTCGATCCTCGCGAAGCGCCTCGTGCAAACCACCT
ACGAATGCATGTGGCTCGGCATCGACCAGGTGAAGCCCGGCGCGCATCTCGGCGACATCGGCCACGCAATTCAGAAGCAT
GCGGAGGCGCAAGGCTACAGCGTCGTGCGCGAATACTGCGGCCACGGCATCGGCACGGTGTTCCATGAAGATCCGCAGGT
CGTCCACTACGGACGCCCCGGCACGGGCATCGAGCTCAAGCCGGGCATGATCTTCACGATCGAGCCGATGATCAACGCCG
GCAAGCGCGACATCCGTACGATGCCCGACCAGTGGACCGTCAAGACCCGCGACCGCAGCCTGTCCGCGCAGTGGGAGCAC
ACGATTCTCGTCACCGAAACAGGCCACGAGGTGCTGACGGTGTCGGCCGGCACGCCGGCGCGCCCGACGTTCGCCGCGCC
GGCGACGGCGGCCTGA

Upstream 100 bases:

>100_bases
ATTCGCGCCAGAATTCGTGCTGCGACGGCCCGCGAAGGGCTGCGACGGCTGGAATAAGGTGCGATAATTGCGCAATTCAC
CGCATTTCAGGCATCGACTC

Downstream 100 bases:

>100_bases
GCGGCTGCGGCGCGCCTCGCGTGCGCCGCAAGCCGCTTCGTTCGCTTCAACCCGCTCGATTTAGCCAGGTAGCCGCTCGC
GTCGTCGCGCGCGGCCGTTC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MAITLKNEHDIAQMRIACRLASEVLDYITPFVVAGVTTGELDRLCHEYMINVQGTVPAPLNYQPPGYPPFPKAICTSVND
VICHGIPGDKTLKNGDALNIDITVIKNGYFGDTSRMFLIGEGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGHAIQKH
AEAQGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
TILVTETGHEVLTVSAGTPARPTFAAPATAA

Sequences:

>Translated_271_residues
MAITLKNEHDIAQMRIACRLASEVLDYITPFVVAGVTTGELDRLCHEYMINVQGTVPAPLNYQPPGYPPFPKAICTSVND
VICHGIPGDKTLKNGDALNIDITVIKNGYFGDTSRMFLIGEGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGHAIQKH
AEAQGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
TILVTETGHEVLTVSAGTPARPTFAAPATAA
>Mature_270_residues
AITLKNEHDIAQMRIACRLASEVLDYITPFVVAGVTTGELDRLCHEYMINVQGTVPAPLNYQPPGYPPFPKAICTSVNDV
ICHGIPGDKTLKNGDALNIDITVIKNGYFGDTSRMFLIGEGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGHAIQKHA
EAQGYSVVREYCGHGIGTVFHEDPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEHT
ILVTETGHEVLTVSAGTPARPTFAAPATAA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=264, Percent_Identity=50, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=40.0793650793651, Blast_Score=191, Evalue=4e-49,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=58.8235294117647, Blast_Score=317, Evalue=4e-88,
Organism=Escherichia coli, GI1788728, Length=254, Percent_Identity=25.9842519685039, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=252, Percent_Identity=47.2222222222222, Blast_Score=223, Evalue=8e-59,
Organism=Saccharomyces cerevisiae, GI6323273, Length=253, Percent_Identity=45.8498023715415, Blast_Score=223, Evalue=2e-59,
Organism=Drosophila melanogaster, GI21355531, Length=262, Percent_Identity=46.5648854961832, Blast_Score=227, Evalue=6e-60,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=39.3574297188755, Blast_Score=192, Evalue=1e-49,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29577; Mature: 29446

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITLKNEHDIAQMRIACRLASEVLDYITPFVVAGVTTGELDRLCHEYMINVQGTVPAPL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCCC
NYQPPGYPPFPKAICTSVNDVICHGIPGDKTLKNGDALNIDITVIKNGYFGDTSRMFLIG
CCCCCCCCCCHHHHHCCCCHHEEECCCCCCEECCCCEEEEEEEEEECCCCCCCCEEEEEE
EGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGHAIQKHAEAQGYSVVREYCGHGIGTV
CCHHHHHHHHHHHHHHEEEEHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEE
FHEDPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
EECCCCEEEECCCCCCEEECCCEEEEECCCCCCCCHHHHCCCCCEEEEECCCCCCCCEEE
TILVTETGHEVLTVSAGTPARPTFAAPATAA
EEEEEECCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AITLKNEHDIAQMRIACRLASEVLDYITPFVVAGVTTGELDRLCHEYMINVQGTVPAPL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCCC
NYQPPGYPPFPKAICTSVNDVICHGIPGDKTLKNGDALNIDITVIKNGYFGDTSRMFLIG
CCCCCCCCCCHHHHHCCCCHHEEECCCCCCEECCCCEEEEEEEEEECCCCCCCCEEEEEE
EGSILAKRLVQTTYECMWLGIDQVKPGAHLGDIGHAIQKHAEAQGYSVVREYCGHGIGTV
CCHHHHHHHHHHHHHHEEEEHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEE
FHEDPQVVHYGRPGTGIELKPGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWEH
EECCCCEEEECCCCCCEEECCCEEEEECCCCCCCCHHHHCCCCCEEEEECCCCCCCCEEE
TILVTETGHEVLTVSAGTPARPTFAAPATAA
EEEEEECCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]