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The map label for this gene is namA [H]

Identifier: 161621448

GI number: 161621448

Start: 4347373

End: 4349667

Strand: Reverse

Name: namA [H]

Synonym: mll5434

Alternate gene names: 161621448

Gene position: 4349667-4347373 (Counterclockwise)

Preceding gene: 13474533

Following gene: 13474531

Centisome position: 61.82

GC content: 63.75

Gene sequence:

>2295_bases
ATGAAGGTTGCGGTTCTCGGCGGCGGTCCAGCCGGCCTCTACTTTGCCATATCGATGAAGCTCAGGGACGCCACGCACGA
TGTGACGGTGTTCGAGCGCAACCGCGCCGACGACACGTTCGGCTGGGGCGTGGTGCTGTCGGCCGAAACGCTCGAGAACC
TCGCTGAGAATGATCCGGTCAGCGCCGTCTGGATCAAGAAGCATTTTGCCTATTGGGACGACATTGCCGTCATCCATGAC
GGCGTTCGCACGGTCTCGTCAGGCCATGGTTTTTGCGGCATCGGCCGCAAGCGGCTGCTGATCCTCTTGCAGCGCCGCGC
CCGCGAGCTCGGCGTCAAGCTGATGTTCGAGACCGATATCGCCGATCCCAAGCCTTACATGGAGACTCATGACCTGGTCG
TCGCCGCCGACGGGCTGAATTCCAGGGCGCGCAACACCTTCGTCGACATCTTCAAGCCCGACATCGACACCCGCAAATGC
AAATTCGTCTGGCTCGGCACCAACCAGAAATTCGACGACGCCTTCACCTTCATCTTCGAGAAGACCGAGCATGGCTGGGT
GTGGGCGCACGCCTACCAGTTCGACAGCGAGACAGCGACCTTCATCGTCGAATGCAGCGAACAGACCTGGGCTGCCTTCG
GCTTCGGCGCGATGACGCAGCAGGAATCGATCGCGGTGTGCGAGCGCATTTTCGCCAAGCATCTCGGCGGCCATGCGCTG
ATGACCAATGCCAACCACATCAGGGGTTCGGCCTGGATCAATTTCCCGCGCGTACTGTGCGAACGCTGGTCGTACAAGAA
CCTGGCGCTGATGGGCGACGCGGCAGCGTCGGCGCATTTCTCGATCGGCTCCGGCACCAAGCTCGCTTTGGAAAGCGCGG
TGGCGCTGGCCGAGTATGTCGAGACGGAACCGGGCCTCGACGCCGCCTTCCGCAAATATGAGGACGCGCGGCGTACCGAG
GTGCTGAAGCTGCAATCGGCGGCGCGCAATTCGCTGGAATGGTTCGAGGAGGTCGAACGCTATCTCGGTCTTGATCCGGT
GCAGTTCAACTATTCGCTGCTGACCCGTTCGCAGCGCATCAGCCACGAGAATTTGCGGCTGCGCGACGCCCAATGGCTGG
GCGGCGCCGAAGAATGGTTCCAGCGCCAGGCCGGTGCCGGCGGCAACAGGCTGCGCCGGGCGCCGATGTTCGCGCCGTTC
AAGCTGCGCGACATGAAGCTGCAAAACCGCGTCGTCGTTTCGCCGATGGCGCAGTACAAGGCCGTCGACGGCTGCCCGAC
CGACTGGCATTTCACCCACTATGCCGAGCGCGCCAAGGGCGGCGCGGGGCTCATCTATATCGAGATGACCTGCGTCAGCC
CGGAAGGCCGTATCACGCCCGGCTGTCCGGGCTTCTACGCGCCTGAGCACGAGGTGGCGTGGAAGCGGCTTGTCGATTTC
GTCCATTCCGAGACCGAGGCCAAGATTTGCGCCCAGATCGGCCATTCCGGTGCCAAGGGCTCGACCCGGCTCGGCTGGGA
AGGCACCGACGTGCCGCTCGCCTCGGGCAATTGGCCTGTCATGGCGGCATCGGCTGTCGCATGGTCGCCTGAGAACCAGG
TGCCGAAGGCGATGGACCGCGCCGACATGGATCTGGTGCGCAACCAGTTCGTGGTCTCGGCCGAGATGGCTGAACGTTGC
GGCTTCGACATGCTGGAGATCCATGCCGCGCATGGCTATCTCCTGTCGTCCTTCATCACGCCTGTCACCAACCGGCGCAC
GGATGAATATGGCGGCTCACTGGAAAACCGCATGCGCTATCCCCTCGAGATCTTCCACGCGGTGCGCGCCGCCTGGCCGG
CGGAGAAGCCGATCTCGATGCGCATTTCGGCCAATGACTGGGTCGGCATCGAAGGCGTCACGCCCGCCGACGCGGTCGAG
ATCGCGCGGCTGCTGCACGAAGCCGGCGTCGACATCTGCGACGTCTCGGCCGGGCAGACATCGGTGTCCGCGAAGCCGAT
CTATGGCCGTATGTTCCAAACACCGTTTTCCGACCGCATCCGCAACGAGGTCGGCATGGCGACGATGGCGGTCGGCAATA
TCTATGAGCCGGACCATGTCAATTCGATCCTGATGGCCGGCCGCGCCGACCTGGTGGCGCTGGCGCGGCCGCATCTGGCC
GATCCCTACTGGACGCTGCATGCGGCGGTGACGCTCGGCGACCGCGGCGTCAAATGGCCGGATCCCTATTTGCCTGGCCG
CGACCAGATCTACCGGTTGGCCGAGCGCGATGCTGCCGCGGGGCTGAAAGTATGA

Upstream 100 bases:

>100_bases
CCGGTATCGGACAATGATTTCGACATAAAACTTTAAGCTTGAAATATTTTGCCGCCGGCGCGATACTCGCAAGGCAGCAA
GCGAAGAGGAGATCGCACAG

Downstream 100 bases:

>100_bases
CGGCGGTACCAGCGATCTCCGGCAAGCATGCGCTGGTCACTGGCGGTGGCTCCGGCGTCGGCCGGGCCATCGCACTTGCG
TTGGCCGGTGCCGGCATCGA

Product: hypothetical protein

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MKVAVLGGGPAGLYFAISMKLRDATHDVTVFERNRADDTFGWGVVLSAETLENLAENDPVSAVWIKKHFAYWDDIAVIHD
GVRTVSSGHGFCGIGRKRLLILLQRRARELGVKLMFETDIADPKPYMETHDLVVAADGLNSRARNTFVDIFKPDIDTRKC
KFVWLGTNQKFDDAFTFIFEKTEHGWVWAHAYQFDSETATFIVECSEQTWAAFGFGAMTQQESIAVCERIFAKHLGGHAL
MTNANHIRGSAWINFPRVLCERWSYKNLALMGDAAASAHFSIGSGTKLALESAVALAEYVETEPGLDAAFRKYEDARRTE
VLKLQSAARNSLEWFEEVERYLGLDPVQFNYSLLTRSQRISHENLRLRDAQWLGGAEEWFQRQAGAGGNRLRRAPMFAPF
KLRDMKLQNRVVVSPMAQYKAVDGCPTDWHFTHYAERAKGGAGLIYIEMTCVSPEGRITPGCPGFYAPEHEVAWKRLVDF
VHSETEAKICAQIGHSGAKGSTRLGWEGTDVPLASGNWPVMAASAVAWSPENQVPKAMDRADMDLVRNQFVVSAEMAERC
GFDMLEIHAAHGYLLSSFITPVTNRRTDEYGGSLENRMRYPLEIFHAVRAAWPAEKPISMRISANDWVGIEGVTPADAVE
IARLLHEAGVDICDVSAGQTSVSAKPIYGRMFQTPFSDRIRNEVGMATMAVGNIYEPDHVNSILMAGRADLVALARPHLA
DPYWTLHAAVTLGDRGVKWPDPYLPGRDQIYRLAERDAAAGLKV

Sequences:

>Translated_764_residues
MKVAVLGGGPAGLYFAISMKLRDATHDVTVFERNRADDTFGWGVVLSAETLENLAENDPVSAVWIKKHFAYWDDIAVIHD
GVRTVSSGHGFCGIGRKRLLILLQRRARELGVKLMFETDIADPKPYMETHDLVVAADGLNSRARNTFVDIFKPDIDTRKC
KFVWLGTNQKFDDAFTFIFEKTEHGWVWAHAYQFDSETATFIVECSEQTWAAFGFGAMTQQESIAVCERIFAKHLGGHAL
MTNANHIRGSAWINFPRVLCERWSYKNLALMGDAAASAHFSIGSGTKLALESAVALAEYVETEPGLDAAFRKYEDARRTE
VLKLQSAARNSLEWFEEVERYLGLDPVQFNYSLLTRSQRISHENLRLRDAQWLGGAEEWFQRQAGAGGNRLRRAPMFAPF
KLRDMKLQNRVVVSPMAQYKAVDGCPTDWHFTHYAERAKGGAGLIYIEMTCVSPEGRITPGCPGFYAPEHEVAWKRLVDF
VHSETEAKICAQIGHSGAKGSTRLGWEGTDVPLASGNWPVMAASAVAWSPENQVPKAMDRADMDLVRNQFVVSAEMAERC
GFDMLEIHAAHGYLLSSFITPVTNRRTDEYGGSLENRMRYPLEIFHAVRAAWPAEKPISMRISANDWVGIEGVTPADAVE
IARLLHEAGVDICDVSAGQTSVSAKPIYGRMFQTPFSDRIRNEVGMATMAVGNIYEPDHVNSILMAGRADLVALARPHLA
DPYWTLHAAVTLGDRGVKWPDPYLPGRDQIYRLAERDAAAGLKV
>Mature_764_residues
MKVAVLGGGPAGLYFAISMKLRDATHDVTVFERNRADDTFGWGVVLSAETLENLAENDPVSAVWIKKHFAYWDDIAVIHD
GVRTVSSGHGFCGIGRKRLLILLQRRARELGVKLMFETDIADPKPYMETHDLVVAADGLNSRARNTFVDIFKPDIDTRKC
KFVWLGTNQKFDDAFTFIFEKTEHGWVWAHAYQFDSETATFIVECSEQTWAAFGFGAMTQQESIAVCERIFAKHLGGHAL
MTNANHIRGSAWINFPRVLCERWSYKNLALMGDAAASAHFSIGSGTKLALESAVALAEYVETEPGLDAAFRKYEDARRTE
VLKLQSAARNSLEWFEEVERYLGLDPVQFNYSLLTRSQRISHENLRLRDAQWLGGAEEWFQRQAGAGGNRLRRAPMFAPF
KLRDMKLQNRVVVSPMAQYKAVDGCPTDWHFTHYAERAKGGAGLIYIEMTCVSPEGRITPGCPGFYAPEHEVAWKRLVDF
VHSETEAKICAQIGHSGAKGSTRLGWEGTDVPLASGNWPVMAASAVAWSPENQVPKAMDRADMDLVRNQFVVSAEMAERC
GFDMLEIHAAHGYLLSSFITPVTNRRTDEYGGSLENRMRYPLEIFHAVRAAWPAEKPISMRISANDWVGIEGVTPADAVE
IARLLHEAGVDICDVSAGQTSVSAKPIYGRMFQTPFSDRIRNEVGMATMAVGNIYEPDHVNSILMAGRADLVALARPHLA
DPYWTLHAAVTLGDRGVKWPDPYLPGRDQIYRLAERDAAAGLKV

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=339, Percent_Identity=28.3185840707965, Blast_Score=133, Evalue=5e-32,
Organism=Escherichia coli, GI1789463, Length=337, Percent_Identity=29.673590504451, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI72001454, Length=270, Percent_Identity=30, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17559804, Length=246, Percent_Identity=31.7073170731707, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=246, Percent_Identity=31.7073170731707, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17565138, Length=293, Percent_Identity=29.0102389078498, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559802, Length=173, Percent_Identity=34.6820809248555, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=270, Percent_Identity=28.1481481481481, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17566914, Length=292, Percent_Identity=26.3698630136986, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17566916, Length=266, Percent_Identity=24.4360902255639, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321973, Length=232, Percent_Identity=31.4655172413793, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325086, Length=237, Percent_Identity=28.2700421940928, Blast_Score=101, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 85130; Mature: 85130

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAVLGGGPAGLYFAISMKLRDATHDVTVFERNRADDTFGWGVVLSAETLENLAENDPV
CEEEEECCCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHCCCCC
SAVWIKKHFAYWDDIAVIHDGVRTVSSGHGFCGIGRKRLLILLQRRARELGVKLMFETDI
EEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHCCEEEEEECCC
ADPKPYMETHDLVVAADGLNSRARNTFVDIFKPDIDTRKCKFVWLGTNQKFDDAFTFIFE
CCCCCCCCCCCEEEEECCCCCCHHHCEEEEECCCCCCCEEEEEEECCCCCCCHHEEEEEE
KTEHGWVWAHAYQFDSETATFIVECSEQTWAAFGFGAMTQQESIAVCERIFAKHLGGHAL
ECCCCEEEEEEEEECCCCEEEEEEECCCCEEHHCCCCCCCHHHHHHHHHHHHHHCCCCEE
MTNANHIRGSAWINFPRVLCERWSYKNLALMGDAAASAHFSIGSGTKLALESAVALAEYV
EECCCCCCCCEEECHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHH
ETEPGLDAAFRKYEDARRTEVLKLQSAARNSLEWFEEVERYLGLDPVQFNYSLLTRSQRI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHC
SHENLRLRDAQWLGGAEEWFQRQAGAGGNRLRRAPMFAPFKLRDMKLQNRVVVSPMAQYK
CCCCCEEECHHHCCCHHHHHHHHCCCCCCHHCCCCCCCCCEEECCCCCCEEEECCHHHHH
AVDGCPTDWHFTHYAERAKGGAGLIYIEMTCVSPEGRITPGCPGFYAPEHEVAWKRLVDF
CCCCCCCCCCHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
VHSETEAKICAQIGHSGAKGSTRLGWEGTDVPLASGNWPVMAASAVAWSPENQVPKAMDR
HHCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHH
ADMDLVRNQFVVSAEMAERCGFDMLEIHAAHGYLLSSFITPVTNRRTDEYGGSLENRMRY
HHHHHHHHHHEEEHHHHHHCCCCEEEEHHHHHHHHHHHHCHHCCCCCHHHCCCHHHHCCC
PLEIFHAVRAAWPAEKPISMRISANDWVGIEGVTPADAVEIARLLHEAGVDICDVSAGQT
HHHHHHHHHHCCCCCCCEEEEEECCCEECCCCCCCHHHHHHHHHHHHCCCCEEECCCCCC
SVSAKPIYGRMFQTPFSDRIRNEVGMATMAVGNIYEPDHVNSILMAGRADLVALARPHLA
CCCCCCCHHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCC
DPYWTLHAAVTLGDRGVKWPDPYLPGRDQIYRLAERDAAAGLKV
CCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKVAVLGGGPAGLYFAISMKLRDATHDVTVFERNRADDTFGWGVVLSAETLENLAENDPV
CEEEEECCCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHCCCCC
SAVWIKKHFAYWDDIAVIHDGVRTVSSGHGFCGIGRKRLLILLQRRARELGVKLMFETDI
EEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHCCEEEEEECCC
ADPKPYMETHDLVVAADGLNSRARNTFVDIFKPDIDTRKCKFVWLGTNQKFDDAFTFIFE
CCCCCCCCCCCEEEEECCCCCCHHHCEEEEECCCCCCCEEEEEEECCCCCCCHHEEEEEE
KTEHGWVWAHAYQFDSETATFIVECSEQTWAAFGFGAMTQQESIAVCERIFAKHLGGHAL
ECCCCEEEEEEEEECCCCEEEEEEECCCCEEHHCCCCCCCHHHHHHHHHHHHHHCCCCEE
MTNANHIRGSAWINFPRVLCERWSYKNLALMGDAAASAHFSIGSGTKLALESAVALAEYV
EECCCCCCCCEEECHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHH
ETEPGLDAAFRKYEDARRTEVLKLQSAARNSLEWFEEVERYLGLDPVQFNYSLLTRSQRI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHC
SHENLRLRDAQWLGGAEEWFQRQAGAGGNRLRRAPMFAPFKLRDMKLQNRVVVSPMAQYK
CCCCCEEECHHHCCCHHHHHHHHCCCCCCHHCCCCCCCCCEEECCCCCCEEEECCHHHHH
AVDGCPTDWHFTHYAERAKGGAGLIYIEMTCVSPEGRITPGCPGFYAPEHEVAWKRLVDF
CCCCCCCCCCHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
VHSETEAKICAQIGHSGAKGSTRLGWEGTDVPLASGNWPVMAASAVAWSPENQVPKAMDR
HHCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHH
ADMDLVRNQFVVSAEMAERCGFDMLEIHAAHGYLLSSFITPVTNRRTDEYGGSLENRMRY
HHHHHHHHHHEEEHHHHHHCCCCEEEEHHHHHHHHHHHHCHHCCCCCHHHCCCHHHHCCC
PLEIFHAVRAAWPAEKPISMRISANDWVGIEGVTPADAVEIARLLHEAGVDICDVSAGQT
HHHHHHHHHHCCCCCCCEEEEEECCCEECCCCCCCHHHHHHHHHHHHCCCCEEECCCCCC
SVSAKPIYGRMFQTPFSDRIRNEVGMATMAVGNIYEPDHVNSILMAGRADLVALARPHLA
CCCCCCCHHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCC
DPYWTLHAAVTLGDRGVKWPDPYLPGRDQIYRLAERDAAAGLKV
CCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA