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The map label for this gene is etfA [H]

Identifier: 161525411

GI number: 161525411

Start: 2454935

End: 2455870

Strand: Reverse

Name: etfA [H]

Synonym: Bmul_2241

Alternate gene names: 161525411

Gene position: 2455870-2454935 (Counterclockwise)

Preceding gene: 161525412

Following gene: 161525409

Centisome position: 71.22

GC content: 65.49

Gene sequence:

>936_bases
ATGACGATTCTGGTAATTGCAGAACACGACAACGCGTCGATCAAGGCCGCGACGCTGAACACGGTGGCGGCGGCGCAGAA
GATCGGCGGCGACATTCACGTGCTGGTCGCCGGTCACAACGCGCAGGGCGCAGCCGATGCGGCCGCGAAGATCGCCGGCG
TGTCGAAGGTGCTGCTGGCCGACGCGCCGCAGCTCGAAGCGGGCCTCGCGGAAAACGTCGAAGCAACGGCGCTGAACATC
GCGAAGGACTATTCGCACATCCTCGCGCCGGCAACCGCGTACGGCAAGAACATCGCACCGCGTATCGCCGCGAAGCTCGA
CGTCGCGCAGATCTCGGATATCACGGCGGTCGATAGTGCCGATACGTTCGAGCGCCCGATTTACGCCGGCAACGCGATCG
CGACGGTGCAGTCGAGCGACCCGATCAAGGTCATCACCGTGCGGGCGACGGGTTTCGATCCGGTCGCAGCCGAAGGCGGC
AGCGCATCGGTCGAGAAGATCGAAGCCGCCGCCGATGCAGGCAAGTCGCAGTTCGTGAGCCGTGAAGTGACGAAGCTGGA
CCGTCCGGAGCTGACCTCGGCGAGCATCATCGTGTCGGGTGGCCGCGGTCTGGGCAGCGGCGAGAACTACACGAAGGTGC
TGGAGCCGCTGGCAGACAAGCTGTCGGCCGCACTCGGCGCCTCGCGCGCGGCAGTCGACGCGGGCTACGTGCCGAACGAC
TATCAGGTCGGCCAGACCGGCAAGATCGTCGCGCCGCAGCTGTACATCGCGGTCGGCATCTCGGGCGCGATCCAGCACCT
GGCCGGCATGAAGGATTCGAAGGTGATCGTCGCGATCAACAAGGATCCCGAAGCACCGATCTTCAGCGTGGCCGACTATG
GCCTCGTCGGCGATCTGTTCACGCTCGTGCCGGAGCTCGTCAGCGAGCTTGGCTGA

Upstream 100 bases:

>100_bases
GCCGCCGAAGCGCGCGGCCGGCGTGAAGGTGCCGGACGTGAAGACGCTGGTCGAGAAGCTGAAGACCGAAGCCAAGGTGC
TGTAAAGGGAGCGGAAAGAA

Downstream 100 bases:

>100_bases
TGCGGCGTGACGCGACGCGGCGATAAGCAGCGTCAAGCAGCGAAACGAGGGGCGCGACGAGCGCCCCTTTTTCGTTTCGG
CGGAAAGCGGCGGGACTGTG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTILVIAEHDNASIKAATLNTVAAAQKIGGDIHVLVAGHNAQGAADAAAKIAGVSKVLLADAPQLEAGLAENVEATALNI
AKDYSHILAPATAYGKNIAPRIAAKLDVAQISDITAVDSADTFERPIYAGNAIATVQSSDPIKVITVRATGFDPVAAEGG
SASVEKIEAAADAGKSQFVSREVTKLDRPELTSASIIVSGGRGLGSGENYTKVLEPLADKLSAALGASRAAVDAGYVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLVGDLFTLVPELVSELG

Sequences:

>Translated_311_residues
MTILVIAEHDNASIKAATLNTVAAAQKIGGDIHVLVAGHNAQGAADAAAKIAGVSKVLLADAPQLEAGLAENVEATALNI
AKDYSHILAPATAYGKNIAPRIAAKLDVAQISDITAVDSADTFERPIYAGNAIATVQSSDPIKVITVRATGFDPVAAEGG
SASVEKIEAAADAGKSQFVSREVTKLDRPELTSASIIVSGGRGLGSGENYTKVLEPLADKLSAALGASRAAVDAGYVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLVGDLFTLVPELVSELG
>Mature_310_residues
TILVIAEHDNASIKAATLNTVAAAQKIGGDIHVLVAGHNAQGAADAAAKIAGVSKVLLADAPQLEAGLAENVEATALNIA
KDYSHILAPATAYGKNIAPRIAAKLDVAQISDITAVDSADTFERPIYAGNAIATVQSSDPIKVITVRATGFDPVAAEGGS
ASVEKIEAAADAGKSQFVSREVTKLDRPELTSASIIVSGGRGLGSGENYTKVLEPLADKLSAALGASRAAVDAGYVPNDY
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLVGDLFTLVPELVSELG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=58.8424437299035, Blast_Score=352, Evalue=2e-97,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=59.6363636363636, Blast_Score=315, Evalue=5e-86,
Organism=Escherichia coli, GI1787990, Length=255, Percent_Identity=34.5098039215686, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1786226, Length=232, Percent_Identity=35.7758620689655, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082157, Length=229, Percent_Identity=32.3144104803493, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17506929, Length=312, Percent_Identity=56.0897435897436, Blast_Score=332, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6325261, Length=319, Percent_Identity=44.8275862068966, Blast_Score=260, Evalue=2e-70,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=60.8974358974359, Blast_Score=357, Evalue=8e-99,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=60.8974358974359, Blast_Score=357, Evalue=8e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31673; Mature: 31542

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVIAEHDNASIKAATLNTVAAAQKIGGDIHVLVAGHNAQGAADAAAKIAGVSKVLLA
CEEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHC
DAPQLEAGLAENVEATALNIAKDYSHILAPATAYGKNIAPRIAAKLDVAQISDITAVDSA
CCCCHHHCHHCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHCCHHHHCCEEECCCC
DTFERPIYAGNAIATVQSSDPIKVITVRATGFDPVAAEGGSASVEKIEAAADAGKSQFVS
CHHCCCEECCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCHHHHHH
REVTKLDRPELTSASIIVSGGRGLGSGENYTKVLEPLADKLSAALGASRAAVDAGYVPND
HHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLVGDLF
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEHHCCCHHHHHH
TLVPELVSELG
HHHHHHHHHCC
>Mature Secondary Structure 
TILVIAEHDNASIKAATLNTVAAAQKIGGDIHVLVAGHNAQGAADAAAKIAGVSKVLLA
EEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHC
DAPQLEAGLAENVEATALNIAKDYSHILAPATAYGKNIAPRIAAKLDVAQISDITAVDSA
CCCCHHHCHHCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHCCHHHHCCEEECCCC
DTFERPIYAGNAIATVQSSDPIKVITVRATGFDPVAAEGGSASVEKIEAAADAGKSQFVS
CHHCCCEECCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCHHHHHH
REVTKLDRPELTSASIIVSGGRGLGSGENYTKVLEPLADKLSAALGASRAAVDAGYVPND
HHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLVGDLF
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEHHCCCHHHHHH
TLVPELVSELG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]