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The map label for this gene is pncB [H]

Identifier: 161525373

GI number: 161525373

Start: 2419685

End: 2420884

Strand: Reverse

Name: pncB [H]

Synonym: Bmul_2203

Alternate gene names: 161525373

Gene position: 2420884-2419685 (Counterclockwise)

Preceding gene: 161525380

Following gene: 161525372

Centisome position: 70.2

GC content: 63.83

Gene sequence:

>1200_bases
ATGATCATCACTTCGCTGCTCGACACGGATCTCTATAAATTCACGATGATGCAGGTCGTCCTGCATCACTTCCCGGCCGC
AAGCGTCGAATACCGCTTCAAGTGCCGCACGCCCGGCGTCGACCTCGTGCCGTACATCGACGAGATTCGCGACGAGGTGC
GCGGGCTGTGTGCGCTGCGCTTCACGGACGTCGAGCTCGACTATCTGCGGCGGATGCGCTTCATCAAGAGCGATTTCGTC
GACTTCCTCGCGCTGTTCCATCTGAACGAGAAATACATTTCGATCACGCCCTCGCCGAAGGGCAACGGCGAGATCGACAT
CGAGATCAAGGGGCCGTGGCTGCACACGATCCTGTTCGAGATTCCGGTGCTCGCGATCGTCAACGAAGTCTATTTCCGCA
ACACGCAGCGCGAGCCGGACTATCGCGAGGGCCGCGAGCGGCTGCGCGAGAAGATCAAGCTGCTCGGCGCGAAGCCCGAA
TTCGCCGACTGCAAGATCGCCGACTACGGCACGCGCCGGCGCTTCTCGAAGGTCTGGCACGAGGAGGTCGCGCTCACGCT
GCGCGACGGGCTCGGCGCGCAGTTCGCGGGCACGAGCAACGTCTACTACGCGATGAAGCACGGGCTCACGCCGCTCGGCA
CGATGGCGCACGAATACCTGCAGGCGTGCCAGGCGCTCGGCCCGCGCCTGCGCGACTCGCAGACCTACGGCTTCGAGATG
TGGGCGAAGGAATATCGCGGCGACCTCGGGATCGCGCTGTCGGACGTCTACGGCATGGACGCGTTCCTGAACGACTTCGA
CATGTACTTCTGCAAGCTGTTCGACGGTGCGCGTCACGATTCGGGCGACCCGTTCGAGTGGGGCGAGCGCATGATCCGTC
ATTACGACGCGAACCGCTGCGACCCGCGCACGAAGGTGCTCGTGTTCTCGGACGCGCTTGACATCCCGAAGGTGATGCAG
CTGTACGAGCGCTTCCGCGGCCGCTGCAAGCTCGCGTTCGGCGTCGGCACGAACCTGACCAACGATCTCGGCTACGTGCC
GCTGCAGATCGTGATCAAGATGGTCCGCTGCAACGGGCAGCCGGTCGCGAAGCTGTCGGATTCGCCGGGCAAGAGCATGT
GCGACGACAAGGCCTATCTGGCCTATCTGCGCCAGGTGTTCGGCATCGCGCAGCCGGCCGACGACGACGCGGCGGCGTGA

Upstream 100 bases:

>100_bases
GGTTTCGCGATGGTCCGGCACGCATTCGGGTAACATGGCCGGCAGACCGGGCGGCGCGCGGTGCGCCGGCACGGGTCACG
ATACTGGCGGTGCCGTCATC

Downstream 100 bases:

>100_bases
GCGCCGGCCGCACGGCCGAAGGTGCGTGCGCAAAGAGGCGGCCGGTATAATCCGGCGGGTATCGAACGAACGCCAACGTC
ACGAGGACGCTTCATGGACA

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFKCRTPGVDLVPYIDEIRDEVRGLCALRFTDVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIEIKGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGAQFAGTSNVYYAMKHGLTPLGTMAHEYLQACQALGPRLRDSQTYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMIRHYDANRCDPRTKVLVFSDALDIPKVMQ
LYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPADDDAAA

Sequences:

>Translated_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFKCRTPGVDLVPYIDEIRDEVRGLCALRFTDVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIEIKGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGAQFAGTSNVYYAMKHGLTPLGTMAHEYLQACQALGPRLRDSQTYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMIRHYDANRCDPRTKVLVFSDALDIPKVMQ
LYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPADDDAAA
>Mature_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFKCRTPGVDLVPYIDEIRDEVRGLCALRFTDVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIEIKGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGAQFAGTSNVYYAMKHGLTPLGTMAHEYLQACQALGPRLRDSQTYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMIRHYDANRCDPRTKVLVFSDALDIPKVMQ
LYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPADDDAAA

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=393, Percent_Identity=43.5114503816794, Blast_Score=327, Evalue=6e-91,
Organism=Saccharomyces cerevisiae, GI6324783, Length=402, Percent_Identity=30.0995024875622, Blast_Score=192, Evalue=7e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45815; Mature: 45815

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFKCRTPGVDLVPYIDEIRDEVRGLCALR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHEE
FTDVELDYLRRMRFIKSDFVDFLALFHLNEKYISITPSPKGNGEIDIEIKGPWLHTILFE
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHH
IPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
EEVALTLRDGLGAQFAGTSNVYYAMKHGLTPLGTMAHEYLQACQALGPRLRDSQTYGFEM
HHHHHHHHCCCCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMIRHYDANRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
DPRTKVLVFSDALDIPKVMQLYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQ
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPADDDAAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFKCRTPGVDLVPYIDEIRDEVRGLCALR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHEE
FTDVELDYLRRMRFIKSDFVDFLALFHLNEKYISITPSPKGNGEIDIEIKGPWLHTILFE
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHH
IPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
EEVALTLRDGLGAQFAGTSNVYYAMKHGLTPLGTMAHEYLQACQALGPRLRDSQTYGFEM
HHHHHHHHCCCCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMIRHYDANRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
DPRTKVLVFSDALDIPKVMQLYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQ
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPADDDAAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA