Click here to switch to the map view.

The map label for this gene is fabF [H]

Identifier: 161525349

GI number: 161525349

Start: 2395399

End: 2396631

Strand: Reverse

Name: fabF [H]

Synonym: Bmul_2179

Alternate gene names: 161525349

Gene position: 2396631-2395399 (Counterclockwise)

Preceding gene: 161525350

Following gene: 161525348

Centisome position: 69.5

GC content: 66.02

Gene sequence:

>1233_bases
GTGAGCCGCCGTCGTGTTGTCGTTACAGGCCTGGGGCTGATTTCGCCTGTTGGCAATAATGTTGCCGACGGCTGGGCCAA
TCTCGTCGCCGGCAAGTCCGGTATCGCCACCGTCACGAAGTTCGATGCGTCGAACCTGGCCGTGCATTTCGCGGGCGAGG
TAAAGGGTTTCAACGCCGAGGAATACATCCCGGCGAAGGAAGCCCGCAACATGGATACGTTCATCCATTACGGCATCGCG
GCCGGCATCCAGGCGCTGAAGGACAGCGGCCTGGAAGTGACCGAAGCGAATGCCGAACGCATCGGCGTGCTGGTCGGCTC
GGGCATCGGCGGTCTGCCGATGATCGAAGACACGCACCAGACCTACGTCGATCGCGGCGCACGCCGTATTTCGCCGTTTT
TCGTGCCGGGTTCGATCATCAACATGATCTCGGGCCACCTGAGCATCATGTTCGGCCTGAAGGGCCCGAACCTCGCCGCC
GTCACGGCCTGCACGACCGGGCTGCACAGCATCGGCCTCGCGGCGCGCCTGATCCAGGCCGGCGACGCGGACGTGATGGT
CGCCGGCGGCGCCGAATCGACGGTGTCGCCGCTCGGCATCGGCGGCTTCGCGGCCGCGCGTGCGCTGTCGACCCGCAACG
ACGATCCGGCCACCGCATCGCGTCCGTGGGACAAGGACCGCGACGGCTTCGTGCTCGGCGAAGGGGCCGGCGTGATGGTG
CTCGAGGAGTACGAATCGGCGAAGGCGCGCGGCGCGAAGATCTACGCGGAAGTCGCGGGCTTCGGCATGACGGGCGACGC
GTACCACATGACCGCGCCGAACATGGACGGCCCGCGCCGCTGCATGGTCGCGGCGCTGCGCGACGCCGGCGTGAACGCGG
ACGAGGTCCAGTACCTGAACGCGCACGGCACGTCGACGCCGCTCGGCGACAAGAACGAATCCGACGCGGTGAAGGCGGCT
TTCGGCGATCACGCGTACAAGATCGTCGTGAACTCGACGAAGTCGATGACGGGCCACCTGCTGGGCGGCGCGGGCGGCCT
CGAATCGGTGTTCACGGTGCTCGCGCTGCACAACAACGTGTCGCCGCCGACCATCAACATCTTCAACCAGGACCCGGAGT
GCGATCTCGACTACTGCGCGAACACCGCGCGTGAGATGAAGATCGACGTGGCCGTGAAGAACAACTTCGGCTTCGGCGGC
ACCAACGGCACGCTGGTGTTCAAGCGCGTCTGA

Upstream 100 bases:

>100_bases
GCATCCTCGCCGGACGGACTAACAGCCACAGGGCTCGCAGGGCTGGTTCCTGTGGCCACTGTGGCTTTTGTTTTTGTCAT
CCAATGGAAAAGAGGTTACC

Downstream 100 bases:

>100_bases
CGCCCACATCGCTTGACGAGTCCATTCGATGCACCGGCCGGGCGTCCGCAGCGTTTCTCGCTGCGGGCCTCGGCCGTGTC
GTATGTCGTGCTGGCCGCGT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDASNLAVHFAGEVKGFNAEEYIPAKEARNMDTFIHYGIA
AGIQALKDSGLEVTEANAERIGVLVGSGIGGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAA
VTACTTGLHSIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPATASRPWDKDRDGFVLGEGAGVMV
LEEYESAKARGAKIYAEVAGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNADEVQYLNAHGTSTPLGDKNESDAVKAA
FGDHAYKIVVNSTKSMTGHLLGGAGGLESVFTVLALHNNVSPPTINIFNQDPECDLDYCANTAREMKIDVAVKNNFGFGG
TNGTLVFKRV

Sequences:

>Translated_410_residues
MSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDASNLAVHFAGEVKGFNAEEYIPAKEARNMDTFIHYGIA
AGIQALKDSGLEVTEANAERIGVLVGSGIGGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAA
VTACTTGLHSIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPATASRPWDKDRDGFVLGEGAGVMV
LEEYESAKARGAKIYAEVAGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNADEVQYLNAHGTSTPLGDKNESDAVKAA
FGDHAYKIVVNSTKSMTGHLLGGAGGLESVFTVLALHNNVSPPTINIFNQDPECDLDYCANTAREMKIDVAVKNNFGFGG
TNGTLVFKRV
>Mature_409_residues
SRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDASNLAVHFAGEVKGFNAEEYIPAKEARNMDTFIHYGIAA
GIQALKDSGLEVTEANAERIGVLVGSGIGGLPMIEDTHQTYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAAV
TACTTGLHSIGLAARLIQAGDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPATASRPWDKDRDGFVLGEGAGVMVL
EEYESAKARGAKIYAEVAGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNADEVQYLNAHGTSTPLGDKNESDAVKAAF
GDHAYKIVVNSTKSMTGHLLGGAGGLESVFTVLALHNNVSPPTINIFNQDPECDLDYCANTAREMKIDVAVKNNFGFGGT
NGTLVFKRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=46.875, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI223972627, Length=148, Percent_Identity=52.027027027027, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI41872631, Length=438, Percent_Identity=23.2876712328767, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1787337, Length=413, Percent_Identity=61.0169491525424, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1788663, Length=412, Percent_Identity=38.5922330097087, Blast_Score=246, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=35.1941747572816, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI71983535, Length=255, Percent_Identity=39.2156862745098, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI212642053, Length=417, Percent_Identity=23.021582733813, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=414, Percent_Identity=24.6376811594203, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320904, Length=449, Percent_Identity=35.1893095768374, Blast_Score=259, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24644341, Length=418, Percent_Identity=44.2583732057416, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI221330659, Length=369, Percent_Identity=24.1192411924119, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19920632, Length=369, Percent_Identity=24.1192411924119, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24581345, Length=430, Percent_Identity=22.093023255814, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42806; Mature: 42675

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDASNLAVHFAGEVKGFNAE
CCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCHH
EYIPAKEARNMDTFIHYGIAAGIQALKDSGLEVTEANAERIGVLVGSGIGGLPMIEDTHQ
HCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCCCCCCCHHH
TYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAAVTACTTGLHSIGLAARLIQA
HHHHCCHHHCCCEECCHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHC
GDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPATASRPWDKDRDGFVLGEGAGVMV
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYESAKARGAKIYAEVAGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNADEVQYLN
EECCHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEE
AHGTSTPLGDKNESDAVKAAFGDHAYKIVVNSTKSMTGHLLGGAGGLESVFTVLALHNNV
CCCCCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHCCC
SPPTINIFNQDPECDLDYCANTAREMKIDVAVKNNFGFGGTNGTLVFKRV
CCCEEEEECCCCCCCHHHHCCCCCEEEEEEEEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIATVTKFDASNLAVHFAGEVKGFNAE
CCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCHH
EYIPAKEARNMDTFIHYGIAAGIQALKDSGLEVTEANAERIGVLVGSGIGGLPMIEDTHQ
HCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCCCCCCCHHH
TYVDRGARRISPFFVPGSIINMISGHLSIMFGLKGPNLAAVTACTTGLHSIGLAARLIQA
HHHHCCHHHCCCEECCHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHC
GDADVMVAGGAESTVSPLGIGGFAAARALSTRNDDPATASRPWDKDRDGFVLGEGAGVMV
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYESAKARGAKIYAEVAGFGMTGDAYHMTAPNMDGPRRCMVAALRDAGVNADEVQYLN
EECCHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEE
AHGTSTPLGDKNESDAVKAAFGDHAYKIVVNSTKSMTGHLLGGAGGLESVFTVLALHNNV
CCCCCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHCCC
SPPTINIFNQDPECDLDYCANTAREMKIDVAVKNNFGFGGTNGTLVFKRV
CCCEEEEECCCCCCCHHHHCCCCCEEEEEEEEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]