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The map label for this gene is aaeR [H]

Identifier: 161525324

GI number: 161525324

Start: 2370951

End: 2371868

Strand: Direct

Name: aaeR [H]

Synonym: Bmul_2154

Alternate gene names: 161525324

Gene position: 2370951-2371868 (Clockwise)

Preceding gene: 161525321

Following gene: 161525325

Centisome position: 68.75

GC content: 71.02

Gene sequence:

>918_bases
ATGAACGATAACGCCCGAGATCTGAACGATCTCTACTACTTCGTCCAGGCGGTCGAACACGGCGGTTTCGCGCCGGCCGG
GCGCGCGCTGAACATGCCGAAGTCGAAACTGAGCCGCCGTATCGCGCTCCTGGAAGCGCGGCTCGGCATCCGGCTGATCC
AGCGCTCGACGCGCCGCTTCACCGTCACCGACGTCGGCCAGACCTACTACGCGCACTGCCGCGCAATGCTCGTCGAAGCC
GACGCCGCGGACGAGGCCGTCGCGTTGCTGCACGAGGAGCCGCGCGGCATCGTGCGTGTCAGCTGTCCGATCGTGCTGCT
CGATTCGCTTGTCGGCGACATGATCGCGGCGTTCATGCTCGCGTGCCCGCGCGTCGAGATCCATCTGGAAGCGACGAACC
GGCGCGTCGACGTGGTCGGCGAAGGGATCGACGTCGCGATTCGCGTCCGGCCGCCGCCGCTCGACGACAGCGATCTCGCG
CTGCGCGTGCTCGCCGAGCGCGGCCAGTGCCTCGTCGCGAGCCCTGCTTTGCTGCGCGAGCACGGCACGCCGGCTGTGCC
CGCCGACCTCGCACGGCTGCCGAGCCTCGATCACGGCGTGCCGCAGGCCGCGCACGTGTGGCGCCTGCGCGGGCCCGACG
GCGCCAGCGCGGAAATCCATCACCAGCCGCGTTTCGTGACGGGCGGCATGCTCGCGCTGCGCGCGGCCGCCGTTGCGGGC
GTCGGCATCGTGCAGTTGCCGACGATGATGGTGCGCGACGAACTCGCGCGCGGCACGCTCGTGACCGTGCTGCCCGACTG
GGCGCCGCGGCGCGAGATCGTCCACGCGGTGTTCGCGTCGCGCCGCGGCTTGCTGCCCGCCGTGCGCGCGCTGCTCGACT
TTCTCGCGGCGCGGTTCGCGGAACTCGAACCCGACTGA

Upstream 100 bases:

>100_bases
AATTTGCGGCGAAACCTGTGTTTCGCATCCTTGAGTGTCACTATAGTGGTGGAACGATCGGTCCGGTAGACTGCGAAATC
CGCACTCAGCGTTCTATTTC

Downstream 100 bases:

>100_bases
GCCGGCGTGTCGCCGCGCGCTGCACGTCGCACGCGCGTGCCGTAGACTGCCGTACGCGCGTCGCGCGTTTTTCCAACCTT
TACCGCTTTTCAGCCATGTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNDNARDLNDLYYFVQAVEHGGFAPAGRALNMPKSKLSRRIALLEARLGIRLIQRSTRRFTVTDVGQTYYAHCRAMLVEA
DAADEAVALLHEEPRGIVRVSCPIVLLDSLVGDMIAAFMLACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLDDSDLA
LRVLAERGQCLVASPALLREHGTPAVPADLARLPSLDHGVPQAAHVWRLRGPDGASAEIHHQPRFVTGGMLALRAAAVAG
VGIVQLPTMMVRDELARGTLVTVLPDWAPRREIVHAVFASRRGLLPAVRALLDFLAARFAELEPD

Sequences:

>Translated_305_residues
MNDNARDLNDLYYFVQAVEHGGFAPAGRALNMPKSKLSRRIALLEARLGIRLIQRSTRRFTVTDVGQTYYAHCRAMLVEA
DAADEAVALLHEEPRGIVRVSCPIVLLDSLVGDMIAAFMLACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLDDSDLA
LRVLAERGQCLVASPALLREHGTPAVPADLARLPSLDHGVPQAAHVWRLRGPDGASAEIHHQPRFVTGGMLALRAAAVAG
VGIVQLPTMMVRDELARGTLVTVLPDWAPRREIVHAVFASRRGLLPAVRALLDFLAARFAELEPD
>Mature_305_residues
MNDNARDLNDLYYFVQAVEHGGFAPAGRALNMPKSKLSRRIALLEARLGIRLIQRSTRRFTVTDVGQTYYAHCRAMLVEA
DAADEAVALLHEEPRGIVRVSCPIVLLDSLVGDMIAAFMLACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLDDSDLA
LRVLAERGQCLVASPALLREHGTPAVPADLARLPSLDHGVPQAAHVWRLRGPDGASAEIHHQPRFVTGGMLALRAAAVAG
VGIVQLPTMMVRDELARGTLVTVLPDWAPRREIVHAVFASRRGLLPAVRALLDFLAARFAELEPD

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=30.5084745762712, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=29.8969072164948, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI87081978, Length=303, Percent_Identity=31.3531353135314, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=29.4915254237288, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=27.1477663230241, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=23.2876712328767, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787589, Length=297, Percent_Identity=25.2525252525253, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI157672245, Length=212, Percent_Identity=27.3584905660377, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789173, Length=297, Percent_Identity=25.2525252525253, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33237; Mature: 33237

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNARDLNDLYYFVQAVEHGGFAPAGRALNMPKSKLSRRIALLEARLGIRLIQRSTRRF
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
TVTDVGQTYYAHCRAMLVEADAADEAVALLHEEPRGIVRVSCPIVLLDSLVGDMIAAFML
EEEECHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHH
ACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLDDSDLALRVLAERGQCLVASPALLRE
HCCCEEEEEEECCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEECHHHHHH
HGTPAVPADLARLPSLDHGVPQAAHVWRLRGPDGASAEIHHQPRFVTGGMLALRAAAVAG
CCCCCCCHHHHHCCCCCCCCCCHHHEEEEECCCCCCCEECCCCCEEHHHHHHHHHHHHHC
VGIVQLPTMMVRDELARGTLVTVLPDWAPRREIVHAVFASRRGLLPAVRALLDFLAARFA
CCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ELEPD
CCCCC
>Mature Secondary Structure
MNDNARDLNDLYYFVQAVEHGGFAPAGRALNMPKSKLSRRIALLEARLGIRLIQRSTRRF
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
TVTDVGQTYYAHCRAMLVEADAADEAVALLHEEPRGIVRVSCPIVLLDSLVGDMIAAFML
EEEECHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHH
ACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLDDSDLALRVLAERGQCLVASPALLRE
HCCCEEEEEEECCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEECHHHHHH
HGTPAVPADLARLPSLDHGVPQAAHVWRLRGPDGASAEIHHQPRFVTGGMLALRAAAVAG
CCCCCCCHHHHHCCCCCCCCCCHHHEEEEECCCCCCCEECCCCCEEHHHHHHHHHHHHHC
VGIVQLPTMMVRDELARGTLVTVLPDWAPRREIVHAVFASRRGLLPAVRALLDFLAARFA
CCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ELEPD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]