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The map label for this gene is pdxY [H]

Identifier: 161525308

GI number: 161525308

Start: 2352002

End: 2352862

Strand: Direct

Name: pdxY [H]

Synonym: Bmul_2138

Alternate gene names: 161525308

Gene position: 2352002-2352862 (Clockwise)

Preceding gene: 161525306

Following gene: 161525309

Centisome position: 68.2

GC content: 67.71

Gene sequence:

>861_bases
ATGAAAAACGTCCTCAGCATTCAGTCGCACGTCATCTACGGCCACGCCGGCAACAGCGCCGCCGTGTTTCCGATGCAGCG
CCTGGGCGTCAACGTCTGGCCGCTCAACACCGTCCAGCTGTCGAACCACATGCAGTACGGCCACTGGGCCGGCAGCGCGA
TCGACGCCGCGAAGATGGAGCAGCTCGTCGACGGGATCGCCGCGATCGGCGCGCTCAAGCGCTGCGACGCCGTGCTGTCG
GGCTTCGCCGGCTCCCCCGCGCAGGCGCGCGCGACCGTCGAGATCGTGCGCGCCGTGAAGGCGATGAATCCGAACGCGTG
GTACTTCTGCGATCCCGCGATGGGCCAGACGGGCGGCATCCGGCCCGAGCCCGGCGTCGAGGAATTCATCGTCAACGAAA
TGCCGGCGCTCGCGGACGGCATGTCGCCCAATCACACCGAACTGCAGAAACTCGCGGGCCGGCGCATCGAGACCGTCGCC
GAAGCGGTCGACGCATGCCGCACGTTGATCGCGCGCGGCCCGAAGATCATCCTCGTCAAGCATCTGCACGACCGCAACAG
TCCCGCCGACCGCTTCAACATGCTCGCCGTCACCGAAACCGAAGCGTGGATCGGCCAGCGTCCGCTGTATGCGTTTCCGC
GTCATCCGGTCGGCGTCGGCGATCTCACCAGCGCGATCTTCGTCGCACGCCGGCTGCGCGGCGACTCGGTGCGCGCCGCG
TTCGAGCACACGCTCGCGGCCGTGCACGCGGTCGTCAAGGCAACCTACGACGCGCGCCGCTACGAACTCGAACTGATCGC
CGCGCAGGACGAAATCGCGCGCCCGAGCGAATGGTTCGGTGCGTGGGTCACCGACGTCTGA

Upstream 100 bases:

>100_bases
TGACGACGCCGCGCAACACCGTGCGCCGCGCGACTTCCGCGCGCGCGGCGAACTCGGGTATCGTGTGACGTGACCCTGAA
ACGCGAGCCGGCGAATTCCC

Downstream 100 bases:

>100_bases
CGCGTCGCGCCTCCTCGCCGCGCGGTACACACCCTGCGGCTCGCCCTGTCCTCCCGCGCGATCAAATCGCCTCGCGTACC
GCGCCATTTCCGGCCGATCG

Product: pyridoxal kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGALKRCDAVLS
GFAGSPAQARATVEIVRAVKAMNPNAWYFCDPAMGQTGGIRPEPGVEEFIVNEMPALADGMSPNHTELQKLAGRRIETVA
EAVDACRTLIARGPKIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAA
FEHTLAAVHAVVKATYDARRYELELIAAQDEIARPSEWFGAWVTDV

Sequences:

>Translated_286_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGALKRCDAVLS
GFAGSPAQARATVEIVRAVKAMNPNAWYFCDPAMGQTGGIRPEPGVEEFIVNEMPALADGMSPNHTELQKLAGRRIETVA
EAVDACRTLIARGPKIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAA
FEHTLAAVHAVVKATYDARRYELELIAAQDEIARPSEWFGAWVTDV
>Mature_286_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGALKRCDAVLS
GFAGSPAQARATVEIVRAVKAMNPNAWYFCDPAMGQTGGIRPEPGVEEFIVNEMPALADGMSPNHTELQKLAGRRIETVA
EAVDACRTLIARGPKIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAA
FEHTLAAVHAVVKATYDARRYELELIAAQDEIARPSEWFGAWVTDV

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=271, Percent_Identity=32.1033210332103, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1787924, Length=283, Percent_Identity=52.2968197879859, Blast_Score=287, Evalue=6e-79,
Organism=Escherichia coli, GI1788758, Length=264, Percent_Identity=25.7575757575758, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17507759, Length=260, Percent_Identity=30.7692307692308, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17507757, Length=270, Percent_Identity=29.6296296296296, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324354, Length=272, Percent_Identity=31.6176470588235, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320806, Length=275, Percent_Identity=30.1818181818182, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI45553007, Length=292, Percent_Identity=29.1095890410959, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31169; Mature: 31169

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKME
CCCCCEEHHEEEEEECCCCEEECCHHHHCCEECCCCEEECCCCCCCCCCCCCHHHHHHHH
QLVDGIAAIGALKRCDAVLSGFAGSPAQARATVEIVRAVKAMNPNAWYFCDPAMGQTGGI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
RPEPGVEEFIVNEMPALADGMSPNHTELQKLAGRRIETVAEAVDACRTLIARGPKIILVK
CCCCCHHHHHHHCCCHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEE
HLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAA
ECCCCCCCHHHHEEEEEECCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
FEHTLAAVHAVVKATYDARRYELELIAAQDEIARPSEWFGAWVTDV
HHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKME
CCCCCEEHHEEEEEECCCCEEECCHHHHCCEECCCCEEECCCCCCCCCCCCCHHHHHHHH
QLVDGIAAIGALKRCDAVLSGFAGSPAQARATVEIVRAVKAMNPNAWYFCDPAMGQTGGI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
RPEPGVEEFIVNEMPALADGMSPNHTELQKLAGRRIETVAEAVDACRTLIARGPKIILVK
CCCCCHHHHHHHCCCHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEE
HLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAA
ECCCCCCCHHHHEEEEEECCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
FEHTLAAVHAVVKATYDARRYELELIAAQDEIARPSEWFGAWVTDV
HHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA