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The map label for this gene is bphD [H]

Identifier: 161525307

GI number: 161525307

Start: 2350776

End: 2351837

Strand: Reverse

Name: bphD [H]

Synonym: Bmul_2137

Alternate gene names: 161525307

Gene position: 2351837-2350776 (Counterclockwise)

Preceding gene: 161525311

Following gene: 161525304

Centisome position: 68.2

GC content: 68.36

Gene sequence:

>1062_bases
ATGTTTTCGATTCGCAAGATGTTGTCCGCCGTGCGAGCCGCGCTCGTCGGCGCGGGCGTCGCCGCCGCGTGCGCGACGGC
CGTCGCGGCCACCGTGCCGGCCGCGGCCGGCAACGACGGGCCCGCCTACGGCCCGCGGCTGGAAGGCTTCGACTATCCGG
CGCCGCTGCACCGCTACGCCTTCGTGTCGCAGCGCGAAACGCTCGAAATGGTGTACCTCGACGTGCCGCCCGCGCATCCG
AACGGCCGCACGGTCGTGCTGCTGCACGGGAAGAATTTCTGCGCGGCGACGTGGGAAGACACGATCGGCGTGCTGAGTCG
CGCGGGCTACCGCGTGATCGCGCCGGACCAGATCGGCTTTTGCAAGTCGTCGAAGCCCGAGCGCTACCAGTACAGCTTCC
AGCAGCTCGCGCGCAACACGCATGCGCTGCTCGAATCGATCGGCGTGAAGTCGGCCACGCTCGTCGGCCATTCGACCGGC
GGCATGCTCGCGATGCGCTATGCGCTGATGTATCCGAAGGCGACCGAGCAGCTCGTGCTCGTGAACCCGATCGGTCTCGA
AGACTGGAAGGCGCTCGGCGTGCCGCCGCTGTCCGTCGACTATTGGTACGCGCGCGAACTGAAAACGTCGGCGGACGGCA
TTCGCCGCTACGAGCAGGCGACCTACTACGCGGGCAAGTGGGCGCCGTCGTACGAGCGCTGGGTGCAGATGCTGGCCGGC
ATGTATCGCGGGCCGGGCCGCGACATCGTCGCGTGGAATTCCGCGCTGATCTACGACATGATCCTCACGCAGCCGGTCGT
CTACGAGCTCGGCGCGATCCGCGTGCCGACGCTGCTGCTGATCGGCGACAAGGACACGACGGCGATCGGCAAGGACGTCG
CGCCGCCCGACGTGCATGCGAAGCTCGGCCGTTATCCGGAGCTCGCGAAGCGCACGCAGGCCGCGATTCCCGGCGCGCAG
CTCGTCGAATTTCCGACGCTCGGACACGCGCCGCAGATCCAGGATCCGGACGCCTTCCACAAGGCGCTGCTCGACGGGCT
CGACGCGGTGCGCACGCCGTAA

Upstream 100 bases:

>100_bases
AAGTCGCGCGGCGCACGGTGTTGCGCGGCGTCGTCAGCGCGACCCGCGTAGAATCGCGGGGCACGGCGCTGCCCGTGCGT
GTCCAATTACCGTGAACGCC

Downstream 100 bases:

>100_bases
CGCGCAGCCGGGCGCGCGCGGCATGCGGCGGCGCGCATTGGGCCGCGCGCATCTCCGCAGCGGCGCCCGGCGCCGTTGCT
ATCGCCGCTCGCTCGCGAGC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MFSIRKMLSAVRAALVGAGVAAACATAVAATVPAAAGNDGPAYGPRLEGFDYPAPLHRYAFVSQRETLEMVYLDVPPAHP
NGRTVVLLHGKNFCAATWEDTIGVLSRAGYRVIAPDQIGFCKSSKPERYQYSFQQLARNTHALLESIGVKSATLVGHSTG
GMLAMRYALMYPKATEQLVLVNPIGLEDWKALGVPPLSVDYWYARELKTSADGIRRYEQATYYAGKWAPSYERWVQMLAG
MYRGPGRDIVAWNSALIYDMILTQPVVYELGAIRVPTLLLIGDKDTTAIGKDVAPPDVHAKLGRYPELAKRTQAAIPGAQ
LVEFPTLGHAPQIQDPDAFHKALLDGLDAVRTP

Sequences:

>Translated_353_residues
MFSIRKMLSAVRAALVGAGVAAACATAVAATVPAAAGNDGPAYGPRLEGFDYPAPLHRYAFVSQRETLEMVYLDVPPAHP
NGRTVVLLHGKNFCAATWEDTIGVLSRAGYRVIAPDQIGFCKSSKPERYQYSFQQLARNTHALLESIGVKSATLVGHSTG
GMLAMRYALMYPKATEQLVLVNPIGLEDWKALGVPPLSVDYWYARELKTSADGIRRYEQATYYAGKWAPSYERWVQMLAG
MYRGPGRDIVAWNSALIYDMILTQPVVYELGAIRVPTLLLIGDKDTTAIGKDVAPPDVHAKLGRYPELAKRTQAAIPGAQ
LVEFPTLGHAPQIQDPDAFHKALLDGLDAVRTP
>Mature_353_residues
MFSIRKMLSAVRAALVGAGVAAACATAVAATVPAAAGNDGPAYGPRLEGFDYPAPLHRYAFVSQRETLEMVYLDVPPAHP
NGRTVVLLHGKNFCAATWEDTIGVLSRAGYRVIAPDQIGFCKSSKPERYQYSFQQLARNTHALLESIGVKSATLVGHSTG
GMLAMRYALMYPKATEQLVLVNPIGLEDWKALGVPPLSVDYWYARELKTSADGIRRYEQATYYAGKWAPSYERWVQMLAG
MYRGPGRDIVAWNSALIYDMILTQPVVYELGAIRVPTLLLIGDKDTTAIGKDVAPPDVHAKLGRYPELAKRTQAAIPGAQ
LVEFPTLGHAPQIQDPDAFHKALLDGLDAVRTP

Specific function: Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6- oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2-hydroxy-2,4-pentadienoic acid (HPD) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. BphD family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=147, Percent_Identity=32.6530612244898, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR017727 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.7.1.8 [H]

Molecular weight: Translated: 38442; Mature: 38442

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSIRKMLSAVRAALVGAGVAAACATAVAATVPAAAGNDGPAYGPRLEGFDYPAPLHRYA
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
FVSQRETLEMVYLDVPPAHPNGRTVVLLHGKNFCAATWEDTIGVLSRAGYRVIAPDQIGF
HHHCCCEEEEEEEECCCCCCCCCEEEEEECCCCEEECHHHHHHHHHHCCCEEECCCCCCC
CKSSKPERYQYSFQQLARNTHALLESIGVKSATLVGHSTGGMLAMRYALMYPKATEQLVL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCCCEEE
VNPIGLEDWKALGVPPLSVDYWYARELKTSADGIRRYEQATYYAGKWAPSYERWVQMLAG
ECCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
MYRGPGRDIVAWNSALIYDMILTQPVVYELGAIRVPTLLLIGDKDTTAIGKDVAPPDVHA
HHCCCCCCEEEECHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHH
KLGRYPELAKRTQAAIPGAQLVEFPTLGHAPQIQDPDAFHKALLDGLDAVRTP
HHCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSIRKMLSAVRAALVGAGVAAACATAVAATVPAAAGNDGPAYGPRLEGFDYPAPLHRYA
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
FVSQRETLEMVYLDVPPAHPNGRTVVLLHGKNFCAATWEDTIGVLSRAGYRVIAPDQIGF
HHHCCCEEEEEEEECCCCCCCCCEEEEEECCCCEEECHHHHHHHHHHCCCEEECCCCCCC
CKSSKPERYQYSFQQLARNTHALLESIGVKSATLVGHSTGGMLAMRYALMYPKATEQLVL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCCCEEE
VNPIGLEDWKALGVPPLSVDYWYARELKTSADGIRRYEQATYYAGKWAPSYERWVQMLAG
ECCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
MYRGPGRDIVAWNSALIYDMILTQPVVYELGAIRVPTLLLIGDKDTTAIGKDVAPPDVHA
HHCCCCCCEEEECHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHH
KLGRYPELAKRTQAAIPGAQLVEFPTLGHAPQIQDPDAFHKALLDGLDAVRTP
HHCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA