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The map label for this gene is iorA [H]

Identifier: 161525281

GI number: 161525281

Start: 2322508

End: 2322948

Strand: Reverse

Name: iorA [H]

Synonym: Bmul_2111

Alternate gene names: 161525281

Gene position: 2322948-2322508 (Counterclockwise)

Preceding gene: 161525283

Following gene: 161525280

Centisome position: 67.36

GC content: 70.52

Gene sequence:

>441_bases
ATGCGCTTCATGCTGAACGGCCAGCCGTTCGATTTCGACGGCGATCCCGACACGCCGCTGCTGTGGGTCGTGCGCGACGC
GGCCGGCTTGACGGGCACCAAATACGGTTGCGGGATCGGCGCGTGCGGCGCCTGCACCGTGCATCTGGACGGCGAAGCCG
CGCGCTCGTGCGTGCTGCCGGTCGCGGGCGTCGCAGGCCGCTCGGTGACGACGATCGAGGGGCTGTCGCACGATCGCTCG
CATCCGGTGCAGCGCGCGTGGATCGAGAAGGACGTGCCGCAGTGCGGCTATTGCCAGTCGGGGATGGTGATGGCGGCGGC
CGCGCTGCTCGCGCGCCACCGCAAGCCGACCGACGCGCAAATCGACGCGGCCGTCACGAACCTGTGCCGCTGCGCGACCT
ATCAACGCATCCGCGAGGCGATCCATGTCGCGGCCGGCTGA

Upstream 100 bases:

>100_bases
AGGTCATTGGCGCGGTTTTTTACGCCGCCAAGAATCCCTGTCAGGCGATCGCGGCCATCCGCCGGATGGCGAACGGCGAC
GCGCAACAGGGAGACAGACG

Downstream 100 bases:

>100_bases
CGCAGTGCGCGCACCGCTCGTGCCGAGCGCGTCGCGGCGCGTATTCCTGAAGGGCGGCGTCGCGCTCGCGGGCAGCCTGC
TGCTGCCGCTCGCGATCGGC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MRFMLNGQPFDFDGDPDTPLLWVVRDAAGLTGTKYGCGIGACGACTVHLDGEAARSCVLPVAGVAGRSVTTIEGLSHDRS
HPVQRAWIEKDVPQCGYCQSGMVMAAAALLARHRKPTDAQIDAAVTNLCRCATYQRIREAIHVAAG

Sequences:

>Translated_146_residues
MRFMLNGQPFDFDGDPDTPLLWVVRDAAGLTGTKYGCGIGACGACTVHLDGEAARSCVLPVAGVAGRSVTTIEGLSHDRS
HPVQRAWIEKDVPQCGYCQSGMVMAAAALLARHRKPTDAQIDAAVTNLCRCATYQRIREAIHVAAG
>Mature_146_residues
MRFMLNGQPFDFDGDPDTPLLWVVRDAAGLTGTKYGCGIGACGACTVHLDGEAARSCVLPVAGVAGRSVTTIEGLSHDRS
HPVQRAWIEKDVPQCGYCQSGMVMAAAALLARHRKPTDAQIDAAVTNLCRCATYQRIREAIHVAAG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=157, Percent_Identity=37.5796178343949, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=38.8157894736842, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789232, Length=142, Percent_Identity=41.5492957746479, Blast_Score=98, Evalue=2e-22,
Organism=Escherichia coli, GI1786480, Length=163, Percent_Identity=36.1963190184049, Blast_Score=94, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17540638, Length=156, Percent_Identity=42.3076923076923, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=39.8692810457516, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=38.562091503268, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI17737937, Length=151, Percent_Identity=38.4105960264901, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=35.1851851851852, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=35.1851851851852, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647201, Length=150, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647199, Length=151, Percent_Identity=33.7748344370861, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24647193, Length=139, Percent_Identity=35.2517985611511, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15498; Mature: 15498

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFMLNGQPFDFDGDPDTPLLWVVRDAAGLTGTKYGCGIGACGACTVHLDGEAARSCVLP
CCEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCC
VAGVAGRSVTTIEGLSHDRSHPVQRAWIEKDVPQCGYCQSGMVMAAAALLARHRKPTDAQ
CCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCH
IDAAVTNLCRCATYQRIREAIHVAAG
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFMLNGQPFDFDGDPDTPLLWVVRDAAGLTGTKYGCGIGACGACTVHLDGEAARSCVLP
CCEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCC
VAGVAGRSVTTIEGLSHDRSHPVQRAWIEKDVPQCGYCQSGMVMAAAALLARHRKPTDAQ
CCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCH
IDAAVTNLCRCATYQRIREAIHVAAG
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]