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The map label for this gene is mdtA [H]

Identifier: 161525274

GI number: 161525274

Start: 2309498

End: 2310850

Strand: Direct

Name: mdtA [H]

Synonym: Bmul_2104

Alternate gene names: 161525274

Gene position: 2309498-2310850 (Clockwise)

Preceding gene: 161525273

Following gene: 161525275

Centisome position: 66.97

GC content: 68.96

Gene sequence:

>1353_bases
ATGGACAACCAACAAAAGCCCACGCCCCCTTCGAACGATCCCGCTCCCGCTGCCGCACGACGTTCGCGCCGCAGGCTGAC
CGCCGCGGCGCTCGCCGTCGTCGTCATCGGCGGCCTGCTGTGGTGGCATCCGTGGAACCGCACGCCGGCCGGCAAGCCGG
GCGCGGGCAGCGCGGCCAGCAGCGCAGGCGGCGGCCATCGCGGCCGCGGCGGGCCCGCTGCGATGGCGAACGTGCCGCAG
CCCGTGCAGGTCGCGGCCGCGACGCGCGGCGAGATGCCGGTCGTGCTGAGCGCGCTCGGCACCGTGACGCCGCTCGCGAA
CGTGACGGTCAAGACGCAGTTGTCCGGCTATCTGCAGTCGGTCGCGTTCAAGGAAGGCCAGATCGTCAAGAAAGGCGACC
TGCTCGCGCAGATCGACCCGCGCCCGTATCAGGTCGCGCTCGAGAACGCCGAAGGCACGCTCGCACGCGATCAGGCGCTG
CTCGCGACCGCGCGCCTCGACCTGAAGCGCTACCGCACGCTGCTGTCGCAGGATTCGATCGCATCGCAGACGGTCGACAC
GCAGGCATCGCTGGTCAAGCAGTACGAAGGCACCGTGAAAACCGATCAGGCCGCCGTCGATTCGGCGAAGCTGAACCTCA
CGTACGCGCGCATCGTCGCGCCGGTGTCGGGCCGCGTCGGCCTGCGCCAGGTCGATCCGGGCAACTACGTGACGCCCGGC
GACACGAACGGAATCGTCGTGATCACGCAGCTGCAGCCGATGAGCGTGATCTTCACGACCTCGGAAGACAACCTGCCGCA
GATCCTCAAGCAGGTCAACGCGGGCCAGAAGCTGTCGGTCACCGCGTACAACCGCAACAACACGATCCCGCTCGAGACCG
GCTCGCTCGAAACGCTCGACAACCAGATCGACACGAGCACCGGCACCGTGAAGCTGCGCGCGACGTTCGATAACAAGGAA
GGCCTGCTGTTTCCGAATCAGTTCGTCAACACGCGGCTGCTCGTCGACGTGATCCGCGACGCGACGATCGTGCCGACCTC
GGCCGTGCTGACGGGCTCGATCGGCCAGTTCGTCTACATCGTCAAACCGGACAACACGGTGACCGTGCGCAAGGTCAAGG
TCGGTCCGGTCGACGGCGAGCGCACGAGCATCGTCGACGGCGTCGCGGTCGGCGAGCGCGTGGTCACCGACGGCTCCGAC
CGTCTGCGCGAAGGCGCGAAGATCTCGATTCCGGCCGACCAGCCGAAAGGCGCGTCGGGCGCGCACGGCGCGAGCGCGGC
ATCGGCGGCATCGGGCGCGGCCGGCCGTCACGGCGGGCACCGGCGCGGTGCGTCGCAGGCAGCGGCCCAATAA

Upstream 100 bases:

>100_bases
GGGACGCGCCCGGGCCGAGCCGGCCGCCTCCGATACGCCCGCATGCCGCCCTCGCAGTGCGTTCCCCGGCACGCCCGCGC
CGTCTTCCTGACAGAACACG

Downstream 100 bases:

>100_bases
GGCACGGGCCGCTCGATGAATCCGTCCCGCATCTTCATTCTCCGGCCGGTCGGCACCGCCCTTTTGATGGCGGCGATCAT
GCTGGCCGGCCTCGTCGCGC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MDNQQKPTPPSNDPAPAAARRSRRRLTAAALAVVVIGGLLWWHPWNRTPAGKPGAGSAASSAGGGHRGRGGPAAMANVPQ
PVQVAAATRGEMPVVLSALGTVTPLANVTVKTQLSGYLQSVAFKEGQIVKKGDLLAQIDPRPYQVALENAEGTLARDQAL
LATARLDLKRYRTLLSQDSIASQTVDTQASLVKQYEGTVKTDQAAVDSAKLNLTYARIVAPVSGRVGLRQVDPGNYVTPG
DTNGIVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTIPLETGSLETLDNQIDTSTGTVKLRATFDNKE
GLLFPNQFVNTRLLVDVIRDATIVPTSAVLTGSIGQFVYIVKPDNTVTVRKVKVGPVDGERTSIVDGVAVGERVVTDGSD
RLREGAKISIPADQPKGASGAHGASAASAASGAAGRHGGHRRGASQAAAQ

Sequences:

>Translated_450_residues
MDNQQKPTPPSNDPAPAAARRSRRRLTAAALAVVVIGGLLWWHPWNRTPAGKPGAGSAASSAGGGHRGRGGPAAMANVPQ
PVQVAAATRGEMPVVLSALGTVTPLANVTVKTQLSGYLQSVAFKEGQIVKKGDLLAQIDPRPYQVALENAEGTLARDQAL
LATARLDLKRYRTLLSQDSIASQTVDTQASLVKQYEGTVKTDQAAVDSAKLNLTYARIVAPVSGRVGLRQVDPGNYVTPG
DTNGIVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTIPLETGSLETLDNQIDTSTGTVKLRATFDNKE
GLLFPNQFVNTRLLVDVIRDATIVPTSAVLTGSIGQFVYIVKPDNTVTVRKVKVGPVDGERTSIVDGVAVGERVVTDGSD
RLREGAKISIPADQPKGASGAHGASAASAASGAAGRHGGHRRGASQAAAQ
>Mature_450_residues
MDNQQKPTPPSNDPAPAAARRSRRRLTAAALAVVVIGGLLWWHPWNRTPAGKPGAGSAASSAGGGHRGRGGPAAMANVPQ
PVQVAAATRGEMPVVLSALGTVTPLANVTVKTQLSGYLQSVAFKEGQIVKKGDLLAQIDPRPYQVALENAEGTLARDQAL
LATARLDLKRYRTLLSQDSIASQTVDTQASLVKQYEGTVKTDQAAVDSAKLNLTYARIVAPVSGRVGLRQVDPGNYVTPG
DTNGIVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTIPLETGSLETLDNQIDTSTGTVKLRATFDNKE
GLLFPNQFVNTRLLVDVIRDATIVPTSAVLTGSIGQFVYIVKPDNTVTVRKVKVGPVDGERTSIVDGVAVGERVVTDGSD
RLREGAKISIPADQPKGASGAHGASAASAASGAAGRHGGHRRGASQAAAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=374, Percent_Identity=45.9893048128342, Blast_Score=331, Evalue=6e-92,
Organism=Escherichia coli, GI1789665, Length=315, Percent_Identity=33.015873015873, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789929, Length=321, Percent_Identity=30.2180685358255, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786668, Length=332, Percent_Identity=31.9277108433735, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87081951, Length=182, Percent_Identity=31.8681318681319, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081796, Length=341, Percent_Identity=26.3929618768328, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47057; Mature: 47057

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQQKPTPPSNDPAPAAARRSRRRLTAAALAVVVIGGLLWWHPWNRTPAGKPGAGSAAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
SAGGGHRGRGGPAAMANVPQPVQVAAATRGEMPVVLSALGTVTPLANVTVKTQLSGYLQS
CCCCCCCCCCCCHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHH
VAFKEGQIVKKGDLLAQIDPRPYQVALENAEGTLARDQALLATARLDLKRYRTLLSQDSI
HHHCCCCEEECCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
ASQTVDTQASLVKQYEGTVKTDQAAVDSAKLNLTYARIVAPVSGRVGLRQVDPGNYVTPG
HHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEEEEEEEECCCCCCCEEEECCCCEECCC
DTNGIVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTIPLETGSLETLD
CCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCEEEECCCCHHHHH
NQIDTSTGTVKLRATFDNKEGLLFPNQFVNTRLLVDVIRDATIVPTSAVLTGSIGQFVYI
HHCCCCCCEEEEEEEECCCCCEECCHHHHHHHHHHHHHHCCEECCCHHHEECCCCCEEEE
VKPDNTVTVRKVKVGPVDGERTSIVDGVAVGERVVTDGSDRLREGAKISIPADQPKGASG
ECCCCEEEEEEEEECCCCCCHHHHHHHHHHCCEEEECCHHHHHCCCEEEECCCCCCCCCC
AHGASAASAASGAAGRHGGHRRGASQAAAQ
CCCCCHHHHCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MDNQQKPTPPSNDPAPAAARRSRRRLTAAALAVVVIGGLLWWHPWNRTPAGKPGAGSAAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
SAGGGHRGRGGPAAMANVPQPVQVAAATRGEMPVVLSALGTVTPLANVTVKTQLSGYLQS
CCCCCCCCCCCCHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHH
VAFKEGQIVKKGDLLAQIDPRPYQVALENAEGTLARDQALLATARLDLKRYRTLLSQDSI
HHHCCCCEEECCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
ASQTVDTQASLVKQYEGTVKTDQAAVDSAKLNLTYARIVAPVSGRVGLRQVDPGNYVTPG
HHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEEEEEEEECCCCCCCEEEECCCCEECCC
DTNGIVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTIPLETGSLETLD
CCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCEEEECCCCHHHHH
NQIDTSTGTVKLRATFDNKEGLLFPNQFVNTRLLVDVIRDATIVPTSAVLTGSIGQFVYI
HHCCCCCCEEEEEEEECCCCCEECCHHHHHHHHHHHHHHCCEECCCHHHEECCCCCEEEE
VKPDNTVTVRKVKVGPVDGERTSIVDGVAVGERVVTDGSDRLREGAKISIPADQPKGASG
ECCCCEEEEEEEEECCCCCCHHHHHHHHHHCCEEEECCHHHHHCCCEEEECCCCCCCCCC
AHGASAASAASGAAGRHGGHRRGASQAAAQ
CCCCCHHHHCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA