Click here to switch to the map view.

The map label for this gene is nhaR [H]

Identifier: 161525229

GI number: 161525229

Start: 2250713

End: 2251606

Strand: Direct

Name: nhaR [H]

Synonym: Bmul_2059

Alternate gene names: 161525229

Gene position: 2250713-2251606 (Clockwise)

Preceding gene: 161525226

Following gene: 161525230

Centisome position: 65.27

GC content: 72.93

Gene sequence:

>894_bases
ATGCTGAATTTCCGCCATCTCTACTACTTCTGGGTCGTCGTGAAGGAAGGCGGCTTCGCGCGCGCGGCCGAACGGCTCGA
CATGGCCGTGCAGACGATCAGCGCGCAGGTGCGCGAGCTCGAGAAATCGCTCGGCCATGCGTTGCTGCGCCCGGCCGGCC
GCGGCGTCACGATGACCGATGCCGGGCAGGCCGCCTATGCGCGCGCGGAAGCGATCTTCGAGATGGGCCGGCTGATTCCG
GACGAAGTGCGCGCGGCGGCGAGCCGGCCGACCGTGCGGCTCGCGGTGGGCCTCGCGGACGGTATCTCGAAGCTCGCCGC
GCACGCGGTGCTGGCGCCGGTGCTCGACACGCCGACGCTGCGGCTGCTGTGCCACGACGGCGAGCACGACGCGCTGCTCG
CCGAACTCGCGCTGCACCATCTGGATCTCGTGCTCGCCGGCCAGGGGGCGCCGTCCGGATCGAACCTGCGCGTGACGAGC
GAGCGGCTCGTCGCGTCGCCGGTCGACTGGTATGGCCCCGCGGCGCTCGTCACGCCCGCCGCGCGCCAGCGCTTTCCGCA
CACGCTCGCCGAGTTGCCGGTGCTGCTGCCGACCGCGCATTCGGCGCTGCGCGCACGGCTCGACCGCTGGTTCGAGGCGG
AGCGGATCGTGCCGCGCGTGGTGGGCGAATTCGAGGACAGCGCACTGATGGCCGTGTTCGCGGCGCGCGGGCTCGGCGTG
TTTCCGCTCAGCGAACTGGGCGCGAACGATGCGACGCTGCTGCGCGGGCTGCGGCGGCTCGGGCGCGCCGGTGACGTGAC
CGAGGAGATTCACGCGATCCGCTCGCGGCGCGGCGAGCATCATCCGCTGACGGCGCGTCTGCTCGCCGCCGCGCGTGAGG
CGCCGGGCCGCTGA

Upstream 100 bases:

>100_bases
GCCCATGAAAGTGGAAAGTGTCGATCATACTGCGCGACATACTTCGCAAAAATCAGCGAGAATCTGATTTTTGGTTCGGT
TTTTCCGAAGTCTCGATCCG

Downstream 100 bases:

>100_bases
AACGAGCGCGACGTCAAACGAAACTATAATGACGCCCCGGCCATACGCGATTGCCGCGCCTGCGACCCGGCCCCGCCGTT
GCGCGACGGCCTTCGCGCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLNFRHLYYFWVVVKEGGFARAAERLDMAVQTISAQVRELEKSLGHALLRPAGRGVTMTDAGQAAYARAEAIFEMGRLIP
DEVRAAASRPTVRLAVGLADGISKLAAHAVLAPVLDTPTLRLLCHDGEHDALLAELALHHLDLVLAGQGAPSGSNLRVTS
ERLVASPVDWYGPAALVTPAARQRFPHTLAELPVLLPTAHSALRARLDRWFEAERIVPRVVGEFEDSALMAVFAARGLGV
FPLSELGANDATLLRGLRRLGRAGDVTEEIHAIRSRRGEHHPLTARLLAAAREAPGR

Sequences:

>Translated_297_residues
MLNFRHLYYFWVVVKEGGFARAAERLDMAVQTISAQVRELEKSLGHALLRPAGRGVTMTDAGQAAYARAEAIFEMGRLIP
DEVRAAASRPTVRLAVGLADGISKLAAHAVLAPVLDTPTLRLLCHDGEHDALLAELALHHLDLVLAGQGAPSGSNLRVTS
ERLVASPVDWYGPAALVTPAARQRFPHTLAELPVLLPTAHSALRARLDRWFEAERIVPRVVGEFEDSALMAVFAARGLGV
FPLSELGANDATLLRGLRRLGRAGDVTEEIHAIRSRRGEHHPLTARLLAAAREAPGR
>Mature_297_residues
MLNFRHLYYFWVVVKEGGFARAAERLDMAVQTISAQVRELEKSLGHALLRPAGRGVTMTDAGQAAYARAEAIFEMGRLIP
DEVRAAASRPTVRLAVGLADGISKLAAHAVLAPVLDTPTLRLLCHDGEHDALLAELALHHLDLVLAGQGAPSGSNLRVTS
ERLVASPVDWYGPAALVTPAARQRFPHTLAELPVLLPTAHSALRARLDRWFEAERIVPRVVGEFEDSALMAVFAARGLGV
FPLSELGANDATLLRGLRRLGRAGDVTEEIHAIRSRRGEHHPLTARLLAAAREAPGR

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=287, Percent_Identity=32.404181184669, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788297, Length=261, Percent_Identity=31.0344827586207, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32120; Mature: 32120

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFRHLYYFWVVVKEGGFARAAERLDMAVQTISAQVRELEKSLGHALLRPAGRGVTMTD
CCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
AGQAAYARAEAIFEMGRLIPDEVRAAASRPTVRLAVGLADGISKLAAHAVLAPVLDTPTL
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCE
RLLCHDGEHDALLAELALHHLDLVLAGQGAPSGSNLRVTSERLVASPVDWYGPAALVTPA
EEEEECCCHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEHHHHHCCCCCCCCCHHHHCHH
ARQRFPHTLAELPVLLPTAHSALRARLDRWFEAERIVPRVVGEFEDSALMAVFAARGLGV
HHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
FPLSELGANDATLLRGLRRLGRAGDVTEEIHAIRSRRGEHHPLTARLLAAAREAPGR
CCHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLNFRHLYYFWVVVKEGGFARAAERLDMAVQTISAQVRELEKSLGHALLRPAGRGVTMTD
CCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
AGQAAYARAEAIFEMGRLIPDEVRAAASRPTVRLAVGLADGISKLAAHAVLAPVLDTPTL
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCE
RLLCHDGEHDALLAELALHHLDLVLAGQGAPSGSNLRVTSERLVASPVDWYGPAALVTPA
EEEEECCCHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEHHHHHCCCCCCCCCHHHHCHH
ARQRFPHTLAELPVLLPTAHSALRARLDRWFEAERIVPRVVGEFEDSALMAVFAARGLGV
HHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
FPLSELGANDATLLRGLRRLGRAGDVTEEIHAIRSRRGEHHPLTARLLAAAREAPGR
CCHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]