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The map label for this gene is ttuB [H]

Identifier: 161525137

GI number: 161525137

Start: 2164704

End: 2166083

Strand: Reverse

Name: ttuB [H]

Synonym: Bmul_1965

Alternate gene names: 161525137

Gene position: 2166083-2164704 (Counterclockwise)

Preceding gene: 161525138

Following gene: 161525136

Centisome position: 62.81

GC content: 69.06

Gene sequence:

>1380_bases
ATGTCCTCCCGTGCAGGCAAATATGCGGACGCCGAGCTGGTGCTCGTGCCGCGGCCGCAGATCGATGCGGTCTATGCGAA
GGTCGCGCGACGGCTCGTGCCGTTCCTGTTCGTCTGCTATCTGTTCAGCTTCATCGACCGCTCGAACGTCGGCTTCGCGC
AGCTGCAGATGAAGTCGTCGCTCGGCTTCAGCGATGCCGCGTACGGCATCGGGGCGACGATGTTCTTCGTCGGCTATGCG
CTGTTCGAGGTGCCGAGCAATCTGCTGCTGCAGCGCATCGGCGCGCGCGCGACGCTGTTCCGCATCATGGTGCTGTGGGG
CGCGGCGTCCGCCGCGACGATGTTCGTGCGCACGCCGGCCCAGTTCTATCTGCTGCGCTTTCTGCTTGGCGTGTTCGAAG
CGGGCTTCTTTCCCGGCATCGTGCTCTATCTGACGTACTGGTTTCCGTCGAACCGCCGCGCGCGCGTGATCGCGCTGATC
CTGATGGCGAGCGTCGCCGCCGGCTTCGTCACGGGCCCGGTGTCGGGCGTGATCCTGAAGTCGCTGCACGAAGCGGGCGG
GCTCGAAGGCTGGCAGTGGATGTTCGTGCTCGAAGGGCTGCCGACGATGCTCGCGGCCGGCTTCGTGTTCGTACTGCTGC
CGGACCGGCCCGAGCAGGCCGCGTGGCTCGACGATGCCGAGAAGGCGCTGATTCGCGACGCGCTCGCGGAAGGCGGCGAG
CCGCGCGAGCCGCGTTCGCTGCTGCGCGTGCTGTCCGATCCGCGCGCGTACTTGCTCGCGTTCGGCATTTTCGTCAACGG
TTGCGCGGGCTATTTCCTCGCGTTCTGGGTGCCGACGCTGATCCGCGAGCTCGGCGTGGCCGATCCGCGCGCGATCGGCC
TGTACACCGTGATTCCGAACGCATTCGGCATCGTCGCGATGCTCGTCTACGGCCGCCATTCGGATCGTCGCAACGAACAG
CGCCTGCACTGGGCGCTCGCCTTTGTCGTCGCCGCGCTCGGCTTCGTCGCGCTCGGCCGCACGGTGCAGCACAGCCTGCC
GTGGACGATCGCCGCGCTCGCGTTCGGCGGCTCGGCGCTCGTGTCGTCGACGCCGATCTTCTGGGCGATGGCGACGCGCT
ACTTTCCGAAAGGCCGCGCGGCCGCCGGCATCGCGTTCGTCAATTCGCTCGCGAGCCTGTCGGGCGCGAGCCCGGCGCTC
GTCGGGCTCGTCAAGGCACATACCGGCAGCCTCGTGCCCGCGATCGACGCGATGGCCGCGATGCTGGTGGTCGCGGCGCT
CGCGCTCGGCTACGGGATGCGCGATGCGCTGCCCGCGGCCGCGCGCGGACCGAAGGGGCCAAACGGCACGCGCGGCCCGC
ACGGCCCGCACGCCCGGTGA

Upstream 100 bases:

>100_bases
CGTTCGTGCGGTGCCGCGCGACGCGCGCGGCGGCCGCTTCAACGTGCGTGCGGTCGCCGCGTCGGAACGCGGCCGTCCGC
CGGTTTTCTCGAGGGTGACC

Downstream 100 bases:

>100_bases
GCGCGCGCGACGCGGCCGCCGGTCCGACAGTCATTTCATCCATTGAACGGGAGCACGACATGAACGAATCCGACGTGAAA
CGCAGCGTGTCCGCGCAGGA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSSRAGKYADAELVLVPRPQIDAVYAKVARRLVPFLFVCYLFSFIDRSNVGFAQLQMKSSLGFSDAAYGIGATMFFVGYA
LFEVPSNLLLQRIGARATLFRIMVLWGAASAATMFVRTPAQFYLLRFLLGVFEAGFFPGIVLYLTYWFPSNRRARVIALI
LMASVAAGFVTGPVSGVILKSLHEAGGLEGWQWMFVLEGLPTMLAAGFVFVLLPDRPEQAAWLDDAEKALIRDALAEGGE
PREPRSLLRVLSDPRAYLLAFGIFVNGCAGYFLAFWVPTLIRELGVADPRAIGLYTVIPNAFGIVAMLVYGRHSDRRNEQ
RLHWALAFVVAALGFVALGRTVQHSLPWTIAALAFGGSALVSSTPIFWAMATRYFPKGRAAAGIAFVNSLASLSGASPAL
VGLVKAHTGSLVPAIDAMAAMLVVAALALGYGMRDALPAAARGPKGPNGTRGPHGPHAR

Sequences:

>Translated_459_residues
MSSRAGKYADAELVLVPRPQIDAVYAKVARRLVPFLFVCYLFSFIDRSNVGFAQLQMKSSLGFSDAAYGIGATMFFVGYA
LFEVPSNLLLQRIGARATLFRIMVLWGAASAATMFVRTPAQFYLLRFLLGVFEAGFFPGIVLYLTYWFPSNRRARVIALI
LMASVAAGFVTGPVSGVILKSLHEAGGLEGWQWMFVLEGLPTMLAAGFVFVLLPDRPEQAAWLDDAEKALIRDALAEGGE
PREPRSLLRVLSDPRAYLLAFGIFVNGCAGYFLAFWVPTLIRELGVADPRAIGLYTVIPNAFGIVAMLVYGRHSDRRNEQ
RLHWALAFVVAALGFVALGRTVQHSLPWTIAALAFGGSALVSSTPIFWAMATRYFPKGRAAAGIAFVNSLASLSGASPAL
VGLVKAHTGSLVPAIDAMAAMLVVAALALGYGMRDALPAAARGPKGPNGTRGPHGPHAR
>Mature_458_residues
SSRAGKYADAELVLVPRPQIDAVYAKVARRLVPFLFVCYLFSFIDRSNVGFAQLQMKSSLGFSDAAYGIGATMFFVGYAL
FEVPSNLLLQRIGARATLFRIMVLWGAASAATMFVRTPAQFYLLRFLLGVFEAGFFPGIVLYLTYWFPSNRRARVIALIL
MASVAAGFVTGPVSGVILKSLHEAGGLEGWQWMFVLEGLPTMLAAGFVFVLLPDRPEQAAWLDDAEKALIRDALAEGGEP
REPRSLLRVLSDPRAYLLAFGIFVNGCAGYFLAFWVPTLIRELGVADPRAIGLYTVIPNAFGIVAMLVYGRHSDRRNEQR
LHWALAFVVAALGFVALGRTVQHSLPWTIAALAFGGSALVSSTPIFWAMATRYFPKGRAAAGIAFVNSLASLSGASPALV
GLVKAHTGSLVPAIDAMAAMLVVAALALGYGMRDALPAAARGPKGPNGTRGPHGPHAR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=411, Percent_Identity=36.4963503649635, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87082320, Length=428, Percent_Identity=25, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI2367379, Length=289, Percent_Identity=28.0276816608997, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789152, Length=424, Percent_Identity=22.4056603773585, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321698, Length=281, Percent_Identity=24.5551601423488, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=190, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=203, Percent_Identity=28.0788177339901, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319250, Length=295, Percent_Identity=22.3728813559322, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322612, Length=243, Percent_Identity=23.0452674897119, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323032, Length=232, Percent_Identity=26.2931034482759, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49348; Mature: 49216

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRAGKYADAELVLVPRPQIDAVYAKVARRLVPFLFVCYLFSFIDRSNVGFAQLQMKSS
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
LGFSDAAYGIGATMFFVGYALFEVPSNLLLQRIGARATLFRIMVLWGAASAATMFVRTPA
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHCCCH
QFYLLRFLLGVFEAGFFPGIVLYLTYWFPSNRRARVIALILMASVAAGFVTGPVSGVILK
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
SLHEAGGLEGWQWMFVLEGLPTMLAAGFVFVLLPDRPEQAAWLDDAEKALIRDALAEGGE
HHHHHCCCCCHHHHHHHHCHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
PREPRSLLRVLSDPRAYLLAFGIFVNGCAGYFLAFWVPTLIRELGVADPRAIGLYTVIPN
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCH
AFGIVAMLVYGRHSDRRNEQRLHWALAFVVAALGFVALGRTVQHSLPWTIAALAFGGSAL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHH
VSSTPIFWAMATRYFPKGRAAAGIAFVNSLASLSGASPALVGLVKAHTGSLVPAIDAMAA
HHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
MLVVAALALGYGMRDALPAAARGPKGPNGTRGPHGPHAR
HHHHHHHHHCCCHHHHCCHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSRAGKYADAELVLVPRPQIDAVYAKVARRLVPFLFVCYLFSFIDRSNVGFAQLQMKSS
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
LGFSDAAYGIGATMFFVGYALFEVPSNLLLQRIGARATLFRIMVLWGAASAATMFVRTPA
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHCCCH
QFYLLRFLLGVFEAGFFPGIVLYLTYWFPSNRRARVIALILMASVAAGFVTGPVSGVILK
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
SLHEAGGLEGWQWMFVLEGLPTMLAAGFVFVLLPDRPEQAAWLDDAEKALIRDALAEGGE
HHHHHCCCCCHHHHHHHHCHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
PREPRSLLRVLSDPRAYLLAFGIFVNGCAGYFLAFWVPTLIRELGVADPRAIGLYTVIPN
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCH
AFGIVAMLVYGRHSDRRNEQRLHWALAFVVAALGFVALGRTVQHSLPWTIAALAFGGSAL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHH
VSSTPIFWAMATRYFPKGRAAAGIAFVNSLASLSGASPALVGLVKAHTGSLVPAIDAMAA
HHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
MLVVAALALGYGMRDALPAAARGPKGPNGTRGPHGPHAR
HHHHHHHHHCCCHHHHCCHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]