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The map label for this gene is iolB [H]

Identifier: 161525067

GI number: 161525067

Start: 2074009

End: 2074827

Strand: Direct

Name: iolB [H]

Synonym: Bmul_1895

Alternate gene names: 161525067

Gene position: 2074009-2074827 (Clockwise)

Preceding gene: 161525066

Following gene: 161525068

Centisome position: 60.14

GC content: 68.62

Gene sequence:

>819_bases
ATGACGATTTCACCCCTCTTGATCAAGGCCGCCGCCGGCCGCGAAATCTGCAACGTCACGCCCGAATCCGCAGGCTGGCA
GCATGTCGGCTTTCGCGCGCTGCGCCTGAAGGCCGGCGACGCGGAAACGCTCGACACCGGCACGCGCGAACTGTGCGTCG
TCGTGCTGACCGGCACCGTGCGCGCCGACGTCGACGGCGACACGTACGACGCGCTCGGCAAGCGCGACAGCGTGTTCGAA
CCCGTGTCGCCCGACGCGCTCTACGTGCCGGGCGGCAAGACCGTCACGCTGGTTGCGACGCGCGATGCCGAAGTCGCGCT
CTGCACGGCGCCGTATGCGAGCGGCGACAAGCGCGTGCTGCGCCTCGACGGCGAACGGATGCGGCGCACGGTGCGCGGCC
AGGGCACCAATACGCGCTACGTCTGCGACATCCTGATGGGCGACAATCCGGCCGCCGACCGGCTGCTCGTCGTCGAAGTC
GTCACGCCGGCGAGCCATTCGAGCAGCTATCCGCCGCACAAGCACGACCGCGACGCGGCGCCCGACGAGACCTCGCTCGA
GGAAACGTACTACCACCGCATCGATCCGCCGCAGGGTTTCGCGTTCCAGCGCGTGTACACCGACGATCGCAGCCTCGACG
AGGCCTGCGCGGTCGAGAATCACGACGTCGTGATGGTGCCGCGCGGCTATCACCCGGTCGTCGCGCCGCACGGCTACACG
CTGTACTACCTGAACGTGATGGCCGGACCGAGCCGCGCGTGGGCGTTCAAGAACGATCCCGCACACGAATGGATGCTCGA
CGCGACACCGGCCCGCTGA

Upstream 100 bases:

>100_bases
CGCCGAGCTATCAGTATGCGAAGAAGGGTTACGAGTCGCTGCGCGCGATCGTCGACAAGCTCAGCGCGTAACCCGTCACC
TCATTGCGGAGCCCGATCCG

Downstream 100 bases:

>100_bases
GCGCGACGCCGCGCTTGCGCCGGCCACGCAACCGCACCGCTACGGAGGCCGCGATGGGAATGCCGTTTACGCACCGCGAA
CCCGCGCCGTTCGACGACGA

Product: myo-inositol catabolism IolB domain-containing protein

Products: NA

Alternate protein names: 5DG isomerase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTISPLLIKAAAGREICNVTPESAGWQHVGFRALRLKAGDAETLDTGTRELCVVVLTGTVRADVDGDTYDALGKRDSVFE
PVSPDALYVPGGKTVTLVATRDAEVALCTAPYASGDKRVLRLDGERMRRTVRGQGTNTRYVCDILMGDNPAADRLLVVEV
VTPASHSSSYPPHKHDRDAAPDETSLEETYYHRIDPPQGFAFQRVYTDDRSLDEACAVENHDVVMVPRGYHPVVAPHGYT
LYYLNVMAGPSRAWAFKNDPAHEWMLDATPAR

Sequences:

>Translated_272_residues
MTISPLLIKAAAGREICNVTPESAGWQHVGFRALRLKAGDAETLDTGTRELCVVVLTGTVRADVDGDTYDALGKRDSVFE
PVSPDALYVPGGKTVTLVATRDAEVALCTAPYASGDKRVLRLDGERMRRTVRGQGTNTRYVCDILMGDNPAADRLLVVEV
VTPASHSSSYPPHKHDRDAAPDETSLEETYYHRIDPPQGFAFQRVYTDDRSLDEACAVENHDVVMVPRGYHPVVAPHGYT
LYYLNVMAGPSRAWAFKNDPAHEWMLDATPAR
>Mature_271_residues
TISPLLIKAAAGREICNVTPESAGWQHVGFRALRLKAGDAETLDTGTRELCVVVLTGTVRADVDGDTYDALGKRDSVFEP
VSPDALYVPGGKTVTLVATRDAEVALCTAPYASGDKRVLRLDGERMRRTVRGQGTNTRYVCDILMGDNPAADRLLVVEVV
TPASHSSSYPPHKHDRDAAPDETSLEETYYHRIDPPQGFAFQRVYTDDRSLDEACAVENHDVVMVPRGYHPVVAPHGYTL
YYLNVMAGPSRAWAFKNDPAHEWMLDATPAR

Specific function: Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) [H]

COG id: COG3718

COG function: function code G; Uncharacterized enzyme involved in inositol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isomerase iolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR021120
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04962 KduI [H]

EC number: NA

Molecular weight: Translated: 29856; Mature: 29725

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISPLLIKAAAGREICNVTPESAGWQHVGFRALRLKAGDAETLDTGTRELCVVVLTGTV
CCCCCEEEEECCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEECEE
RADVDGDTYDALGKRDSVFEPVSPDALYVPGGKTVTLVATRDAEVALCTAPYASGDKRVL
EECCCCCHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCEEEEECCCCCCCCEEE
RLDGERMRRTVRGQGTNTRYVCDILMGDNPAADRLLVVEVVTPASHSSSYPPHKHDRDAA
EECCHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
PDETSLEETYYHRIDPPQGFAFQRVYTDDRSLDEACAVENHDVVMVPRGYHPVVAPHGYT
CCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCEEEECCCCCCEECCCCEE
LYYLNVMAGPSRAWAFKNDPAHEWMLDATPAR
EEEEEEECCCCCEEEECCCCCCCEEEECCCCC
>Mature Secondary Structure 
TISPLLIKAAAGREICNVTPESAGWQHVGFRALRLKAGDAETLDTGTRELCVVVLTGTV
CCCCEEEEECCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEECEE
RADVDGDTYDALGKRDSVFEPVSPDALYVPGGKTVTLVATRDAEVALCTAPYASGDKRVL
EECCCCCHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCEEEEECCCCCCCCEEE
RLDGERMRRTVRGQGTNTRYVCDILMGDNPAADRLLVVEVVTPASHSSSYPPHKHDRDAA
EECCHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
PDETSLEETYYHRIDPPQGFAFQRVYTDDRSLDEACAVENHDVVMVPRGYHPVVAPHGYT
CCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCEEEECCCCCCEECCCCEE
LYYLNVMAGPSRAWAFKNDPAHEWMLDATPAR
EEEEEEECCCCCEEEECCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA