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The map label for this gene is nanT [H]

Identifier: 161524891

GI number: 161524891

Start: 1898131

End: 1899351

Strand: Direct

Name: nanT [H]

Synonym: Bmul_1718

Alternate gene names: 161524891

Gene position: 1898131-1899351 (Clockwise)

Preceding gene: 161524887

Following gene: 161524892

Centisome position: 55.04

GC content: 66.01

Gene sequence:

>1221_bases
ATGAGCTGGACCCGCGAACAACGCAACGTGACGATTGCCGCCTATCTCGGCTGGACGCTCGATGCGTTCGATTTTTTCCT
GATGGTTTTCGTGCTGAAGGACATCGCGGCGGAATTCGCGTCGACGATCCCGGCCGTCGCGTTCGCGCTGACGCTGACGC
TCGCGATGCGTCCGCTCGGCGCACTCATCTTCGGCCGCCTCGCCGATCGCTTCGGCCGCCGCCCGACGCCGATGGTCAAC
ATCGCGTGCTATTCCGTGCTCGAGCTCGCGTCGGGCTTCGCGCCGAGCCTCACCGCGCTGCTCGTGCTGCGTGCGCTGTT
CGGCATTGCGATGGGCGGCGAATGGGGCGTCGGCTCCGCGCTGACGATGGAGACCGTGCCCACGCACGCGCGCGGCATCG
TGTCGGGCCTGCTGCAGGCCGGCTATCCGAGCGGCTATCTGCTCGCGTCGATCGTGTTCGGCCTCTTCTACCAGTACATC
GGCTGGCGCGGCATGTTCATGATCGGCGTGCTGCCCGCGCTGCTCGTCTTGTATGTGCGCGCGCATGTGCCGGAGTCGCC
CGCGTGGAAGCAGATGGAAAAGCGTGAGCGTCCGAGTCTCGCGACCACGCTGCAGCGAAACTGGAAGCTGACGATCTACG
CGATCGTGCTGATGACCGCGTTCAACTTCTTCTCGCACGGCACGCAGGATCTGTATCCGACCTTCCTGCGCGAGCAGCAC
CACTTCGATCCGCATACGGTGTCGTGGATCACGATCGTGCTGAACATCGGCGCGATCGTCGGCGGCCTCGCGTTCGGCGC
GATCTCGGAGCGGATCGGCCGGCGCCGTGCGATCTTCATCGCCGCGCTGATCGCGCTGCCGGTGCTGCCGCTGTGGGCGT
TCTCGAGCGGCCCGCTCGCGCTCGCGGCCGGCGCCTTCCTGATGCAGATTTCGGTGCAAGGGGCGTGGGGTGTGATTCCG
GTCCACCTCAACGAAATTTCGCCGGACGAGATTCGCGCGACGTTCCCGGGCGTCGTCTATCAGCTCGGCAACCTGCTCGC
GTCCGGCAACGCGACGATGCAGGCGTCGCTCGCCGTCTCGCACGACAACAACTATGCGTTCGCGCTCGCCCTCGTGGCCG
GCACCGTCGCGGTCGTGATCGCGGTGCTGATCCTGTTCAGCCGCGAACGGCGCGGCATCGACATGACGCAATCCGTCAAT
ACGCGTACCGCCGCGACCTAA

Upstream 100 bases:

>100_bases
CGCGCGTCGGCCTACACTCGATCAGTGCCCCGAACCGCGCGCGAATCGGGCCGCACGTCCTTGCGTCCCGCGCGCGCACG
CCAACGAGGAGACCTCGCAC

Downstream 100 bases:

>100_bases
GCAGACGATTTTGCGCATTGCATCACCGCGCGCGGCCCGCAGCGCCTGGGCCGCGCGCCGCGCTTTCCGCATTCGCACAT
CGAACTAGAGGAATCCGACC

Product: major facilitator transporter

Products: NA

Alternate protein names: Sialic acid permease [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVAFALTLTLAMRPLGALIFGRLADRFGRRPTPMVN
IACYSVLELASGFAPSLTALLVLRALFGIAMGGEWGVGSALTMETVPTHARGIVSGLLQAGYPSGYLLASIVFGLFYQYI
GWRGMFMIGVLPALLVLYVRAHVPESPAWKQMEKRERPSLATTLQRNWKLTIYAIVLMTAFNFFSHGTQDLYPTFLREQH
HFDPHTVSWITIVLNIGAIVGGLAFGAISERIGRRRAIFIAALIALPVLPLWAFSSGPLALAAGAFLMQISVQGAWGVIP
VHLNEISPDEIRATFPGVVYQLGNLLASGNATMQASLAVSHDNNYAFALALVAGTVAVVIAVLILFSRERRGIDMTQSVN
TRTAAT

Sequences:

>Translated_406_residues
MSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVAFALTLTLAMRPLGALIFGRLADRFGRRPTPMVN
IACYSVLELASGFAPSLTALLVLRALFGIAMGGEWGVGSALTMETVPTHARGIVSGLLQAGYPSGYLLASIVFGLFYQYI
GWRGMFMIGVLPALLVLYVRAHVPESPAWKQMEKRERPSLATTLQRNWKLTIYAIVLMTAFNFFSHGTQDLYPTFLREQH
HFDPHTVSWITIVLNIGAIVGGLAFGAISERIGRRRAIFIAALIALPVLPLWAFSSGPLALAAGAFLMQISVQGAWGVIP
VHLNEISPDEIRATFPGVVYQLGNLLASGNATMQASLAVSHDNNYAFALALVAGTVAVVIAVLILFSRERRGIDMTQSVN
TRTAAT
>Mature_405_residues
SWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVAFALTLTLAMRPLGALIFGRLADRFGRRPTPMVNI
ACYSVLELASGFAPSLTALLVLRALFGIAMGGEWGVGSALTMETVPTHARGIVSGLLQAGYPSGYLLASIVFGLFYQYIG
WRGMFMIGVLPALLVLYVRAHVPESPAWKQMEKRERPSLATTLQRNWKLTIYAIVLMTAFNFFSHGTQDLYPTFLREQHH
FDPHTVSWITIVLNIGAIVGGLAFGAISERIGRRRAIFIAALIALPVLPLWAFSSGPLALAAGAFLMQISVQGAWGVIPV
HLNEISPDEIRATFPGVVYQLGNLLASGNATMQASLAVSHDNNYAFALALVAGTVAVVIAVLILFSRERRGIDMTQSVNT
RTAAT

Specific function: May be a sugar-cation symporter involved in sialic acid uptake [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter family. Sialic acid transporter (TC 2.A.1.12.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=351, Percent_Identity=28.7749287749288, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI87082231, Length=455, Percent_Identity=26.8131868131868, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1790550, Length=394, Percent_Identity=25.8883248730964, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788292, Length=449, Percent_Identity=24.9443207126949, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786229, Length=386, Percent_Identity=24.8704663212435, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081723, Length=341, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789941, Length=434, Percent_Identity=24.8847926267281, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788942, Length=429, Percent_Identity=24.2424242424242, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17542342, Length=132, Percent_Identity=35.6060606060606, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322632, Length=440, Percent_Identity=28.4090909090909, Blast_Score=172, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004742 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44152; Mature: 44021

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVAFALTLTLAMRPLG
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIFGRLADRFGRRPTPMVNIACYSVLELASGFAPSLTALLVLRALFGIAMGGEWGVGSA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCE
LTMETVPTHARGIVSGLLQAGYPSGYLLASIVFGLFYQYIGWRGMFMIGVLPALLVLYVR
EEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHVPESPAWKQMEKRERPSLATTLQRNWKLTIYAIVLMTAFNFFSHGTQDLYPTFLREQH
HCCCCCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
HFDPHTVSWITIVLNIGAIVGGLAFGAISERIGRRRAIFIAALIALPVLPLWAFSSGPLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHH
LAAGAFLMQISVQGAWGVIPVHLNEISPDEIRATFPGVVYQLGNLLASGNATMQASLAVS
HHHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
HDNNYAFALALVAGTVAVVIAVLILFSRERRGIDMTQSVNTRTAAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
SWTREQRNVTIAAYLGWTLDAFDFFLMVFVLKDIAAEFASTIPAVAFALTLTLAMRPLG
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIFGRLADRFGRRPTPMVNIACYSVLELASGFAPSLTALLVLRALFGIAMGGEWGVGSA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCE
LTMETVPTHARGIVSGLLQAGYPSGYLLASIVFGLFYQYIGWRGMFMIGVLPALLVLYVR
EEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHVPESPAWKQMEKRERPSLATTLQRNWKLTIYAIVLMTAFNFFSHGTQDLYPTFLREQH
HCCCCCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
HFDPHTVSWITIVLNIGAIVGGLAFGAISERIGRRRAIFIAALIALPVLPLWAFSSGPLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHH
LAAGAFLMQISVQGAWGVIPVHLNEISPDEIRATFPGVVYQLGNLLASGNATMQASLAVS
HHHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
HDNNYAFALALVAGTVAVVIAVLILFSRERRGIDMTQSVNTRTAAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA