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The map label for this gene is cobJ [H]

Identifier: 161524744

GI number: 161524744

Start: 1721751

End: 1723466

Strand: Direct

Name: cobJ [H]

Synonym: Bmul_1571

Alternate gene names: 161524744

Gene position: 1721751-1723466 (Clockwise)

Preceding gene: 161524743

Following gene: 161524749

Centisome position: 49.93

GC content: 72.9

Gene sequence:

>1716_bases
ATGACGACGCCGCCGGCGATCGTGGTGCTCGGCGCCGGTGCGCTCGACACCGCGCGACGTATCCAGGCGCGCTATCCGGG
CGCGCAGGTGCACGGGCTCGCATCGCGCGTCGACGCGGACGTGCGCTTCGACGAACTCGGCGCGCATCTGCGCGAACTGT
ATGCGCGCGGGCTGCCGATCGTCGCGCTGTGCGCGGCCGGCATCGTGATCCGCTGCATCGCGCCCGCGCTCGCGGACAAA
GGCGTCGAGCCGCCCGTGCTCGCGGTGGCCGAGGACGGCTCGGCCGTCGTGCCGCTGCTCGGCGGGTTGACCGGCGTCAA
CGCGATCGCACGCGAGATCGCCGCACAACTCGGGATCGCGCCGGCGATCACGACGAGCGGCGAACTGCGATTCGGCGCGT
GCGTGCTGAACCCGCCCGACGGCTATGTGCTCGCCGATCTCGCGCAGGGCAAGCGCTTCGTGTCAGATTTGCTTGCCGGT
GCGTCGACGCGCATCGACGGCCCCGCACCGTGGCTCGACGATGTCGCGCTGCCGCGCGACGCGGCGGCGGCCCATGCGAT
CCGCGTGACGCCCGACGCGGTGCGCGTCGCACGCGACGAACTGGTGATTCATCCGCGCAGCGTCGTGGTCGGCATCGGCA
CGCACGCGAGCCGCGCGGCCGGACCGCTCGCCGTGCGGATCGACGCGCTGCTCGACGCATGCGGGCTTGCACGGCGTGCG
CTCGCGGCGATCGTCGCGCCTGCGTCGGTCATCGGCGATCCGGCGCTCGATGCCGCCGCCGAAGCGCTCGACGTGCCGCT
GCGTTTCGTCGATGCGGACGACGGCGCCGATGCCGGCATGGACGCCGCCGCCCTGCTCGCGCGCGCACTGCGCGTGCCGC
ACGCGTTGCGCGGCGAAGCGGACGGCCTCGCGTGCACGGTCACGACGCAGCCTGTCGATCCCGCGACGCTCGGCCGCGCA
CGCGGCCGCCTGACCGTGCTCGGGCTCGGGCCCGGCGGCGCCGCGTGGCTGACGCCCGCGGCGCGCGCGGCGCTCGCCGA
TGCGACCGACATTCTCGGCTACACGACGTACGTGAACATGGCCGGGCCGTTTCGCGCCGATCAGCGCGTGCACGGCACCG
ACAATCGCGAGGAAATGCAGCGCGCGCGCCATGCGTTCGAGCTGGCGGCCGCCGGCCGGCGTGTGGCGGTCGTATCGTCC
GGCGATCCGGGCGTGTTCGCGATGGCCGCCGCCGTGCTCGAAGCGCTCGACGACGCACGCGATCCGCAGTGGGCGGCCGT
CGACCTGCGGATCGAGCCCGGCGTATCGGCGTCGCTCGCGACTGCCGCACAGGCCGGCGCACCGCTCGGCCACGACTTCT
GCGCGATTTCGCTGTCGGACAACCTGAAGCCGTGGGACGTGATCGAAACGCGTTTGCGGCATGCGGCCGAAGCCGATCTC
GTGATGGCGTTCTACAACCCGATCTCGCGCGCGCGACCTTGGCAGCTCGATCGTGCGCTCGACGTCGTGCGCGCGCACCG
CGCGGCCGATACGGTCGTCGTGCTCGGTCGCGACATCGGCCGCCCCGGCGCGACGCTCGCAACGACGACGCTCGGCGCGC
TGCGCAGCGATCAGGTCGACATGCGCACGATGGTGATCGTGGGCTCGTCGACGACGCGGCGCTTTGCGATCGGCGCCGGA
CGCGAGTGGGTCTATACGCCGCGCTGGTATCGATGA

Upstream 100 bases:

>100_bases
CGACGATGGCGAGCCAGCGCATCGTGCCGCTCGACGAAGTCGATCCGATGGCGTCGCCGTATTTCTCGCTGCTCGTCGTG
CCGGGGGAAAAATGGCAAGG

Downstream 100 bases:

>100_bases
GCGACGCGCCGCGCACCGGGGCGTGCGCGGCAGCGGCACGCCCGCGCGTTACGCGCGCGCGTAATCGGCGAGCAGCCGCG
CCTTCGCGTCGACGAGCAGC

Product: precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MTTPPAIVVLGAGALDTARRIQARYPGAQVHGLASRVDADVRFDELGAHLRELYARGLPIVALCAAGIVIRCIAPALADK
GVEPPVLAVAEDGSAVVPLLGGLTGVNAIAREIAAQLGIAPAITTSGELRFGACVLNPPDGYVLADLAQGKRFVSDLLAG
ASTRIDGPAPWLDDVALPRDAAAAHAIRVTPDAVRVARDELVIHPRSVVVGIGTHASRAAGPLAVRIDALLDACGLARRA
LAAIVAPASVIGDPALDAAAEALDVPLRFVDADDGADAGMDAAALLARALRVPHALRGEADGLACTVTTQPVDPATLGRA
RGRLTVLGLGPGGAAWLTPAARAALADATDILGYTTYVNMAGPFRADQRVHGTDNREEMQRARHAFELAAAGRRVAVVSS
GDPGVFAMAAAVLEALDDARDPQWAAVDLRIEPGVSASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRLRHAAEADL
VMAFYNPISRARPWQLDRALDVVRAHRAADTVVVLGRDIGRPGATLATTTLGALRSDQVDMRTMVIVGSSTTRRFAIGAG
REWVYTPRWYR

Sequences:

>Translated_571_residues
MTTPPAIVVLGAGALDTARRIQARYPGAQVHGLASRVDADVRFDELGAHLRELYARGLPIVALCAAGIVIRCIAPALADK
GVEPPVLAVAEDGSAVVPLLGGLTGVNAIAREIAAQLGIAPAITTSGELRFGACVLNPPDGYVLADLAQGKRFVSDLLAG
ASTRIDGPAPWLDDVALPRDAAAAHAIRVTPDAVRVARDELVIHPRSVVVGIGTHASRAAGPLAVRIDALLDACGLARRA
LAAIVAPASVIGDPALDAAAEALDVPLRFVDADDGADAGMDAAALLARALRVPHALRGEADGLACTVTTQPVDPATLGRA
RGRLTVLGLGPGGAAWLTPAARAALADATDILGYTTYVNMAGPFRADQRVHGTDNREEMQRARHAFELAAAGRRVAVVSS
GDPGVFAMAAAVLEALDDARDPQWAAVDLRIEPGVSASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRLRHAAEADL
VMAFYNPISRARPWQLDRALDVVRAHRAADTVVVLGRDIGRPGATLATTTLGALRSDQVDMRTMVIVGSSTTRRFAIGAG
REWVYTPRWYR
>Mature_570_residues
TTPPAIVVLGAGALDTARRIQARYPGAQVHGLASRVDADVRFDELGAHLRELYARGLPIVALCAAGIVIRCIAPALADKG
VEPPVLAVAEDGSAVVPLLGGLTGVNAIAREIAAQLGIAPAITTSGELRFGACVLNPPDGYVLADLAQGKRFVSDLLAGA
STRIDGPAPWLDDVALPRDAAAAHAIRVTPDAVRVARDELVIHPRSVVVGIGTHASRAAGPLAVRIDALLDACGLARRAL
AAIVAPASVIGDPALDAAAEALDVPLRFVDADDGADAGMDAAALLARALRVPHALRGEADGLACTVTTQPVDPATLGRAR
GRLTVLGLGPGGAAWLTPAARAALADATDILGYTTYVNMAGPFRADQRVHGTDNREEMQRARHAFELAAAGRRVAVVSSG
DPGVFAMAAAVLEALDDARDPQWAAVDLRIEPGVSASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRLRHAAEADLV
MAFYNPISRARPWQLDRALDVVRAHRAADTVVVLGRDIGRPGATLATTTLGALRSDQVDMRTMVIVGSSTTRRFAIGAGR
EWVYTPRWYR

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 59393; Mature: 59261

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPPAIVVLGAGALDTARRIQARYPGAQVHGLASRVDADVRFDELGAHLRELYARGLPI
CCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCH
VALCAAGIVIRCIAPALADKGVEPPVLAVAEDGSAVVPLLGGLTGVNAIAREIAAQLGIA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHCCHHHHHHHHHHHHHHHCCC
PAITTSGELRFGACVLNPPDGYVLADLAQGKRFVSDLLAGASTRIDGPAPWLDDVALPRD
EEECCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCC
AAAAHAIRVTPDAVRVARDELVIHPRSVVVGIGTHASRAAGPLAVRIDALLDACGLARRA
HHHCCEEEECHHHHHHHHHHEEECCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHH
LAAIVAPASVIGDPALDAAAEALDVPLRFVDADDGADAGMDAAALLARALRVPHALRGEA
HHHHHCCHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCCHHHCCCC
DGLACTVTTQPVDPATLGRARGRLTVLGLGPGGAAWLTPAARAALADATDILGYTTYVNM
CCEEEEEECCCCCHHHHHCCCCCEEEEEECCCCCHHHCHHHHHHHHHHHHHHEEEEEEEC
AGPFRADQRVHGTDNREEMQRARHAFELAAAGRRVAVVSSGDPGVFAMAAAVLEALDDAR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
DPQWAAVDLRIEPGVSASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRLRHAAEADL
CCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCC
VMAFYNPISRARPWQLDRALDVVRAHRAADTVVVLGRDIGRPGATLATTTLGALRSDQVD
HHHHHCHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCC
MRTMVIVGSSTTRRFAIGAGREWVYTPRWYR
EEEEEEECCCCCEEEEEECCCCEECCCCCCC
>Mature Secondary Structure 
TTPPAIVVLGAGALDTARRIQARYPGAQVHGLASRVDADVRFDELGAHLRELYARGLPI
CCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCH
VALCAAGIVIRCIAPALADKGVEPPVLAVAEDGSAVVPLLGGLTGVNAIAREIAAQLGIA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHCCHHHHHHHHHHHHHHHCCC
PAITTSGELRFGACVLNPPDGYVLADLAQGKRFVSDLLAGASTRIDGPAPWLDDVALPRD
EEECCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCC
AAAAHAIRVTPDAVRVARDELVIHPRSVVVGIGTHASRAAGPLAVRIDALLDACGLARRA
HHHCCEEEECHHHHHHHHHHEEECCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHH
LAAIVAPASVIGDPALDAAAEALDVPLRFVDADDGADAGMDAAALLARALRVPHALRGEA
HHHHHCCHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCCHHHCCCC
DGLACTVTTQPVDPATLGRARGRLTVLGLGPGGAAWLTPAARAALADATDILGYTTYVNM
CCEEEEEECCCCCHHHHHCCCCCEEEEEECCCCCHHHCHHHHHHHHHHHHHHEEEEEEEC
AGPFRADQRVHGTDNREEMQRARHAFELAAAGRRVAVVSSGDPGVFAMAAAVLEALDDAR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
DPQWAAVDLRIEPGVSASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRLRHAAEADL
CCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCC
VMAFYNPISRARPWQLDRALDVVRAHRAADTVVVLGRDIGRPGATLATTTLGALRSDQVD
HHHHHCHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCC
MRTMVIVGSSTTRRFAIGAGREWVYTPRWYR
EEEEEEECCCCCEEEEEECCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]