Click here to switch to the map view.

The map label for this gene is lrp [C]

Identifier: 161524707

GI number: 161524707

Start: 1690413

End: 1690877

Strand: Direct

Name: lrp [C]

Synonym: Bmul_1534

Alternate gene names: 161524707

Gene position: 1690413-1690877 (Clockwise)

Preceding gene: 161524704

Following gene: 161524709

Centisome position: 49.02

GC content: 65.59

Gene sequence:

>465_bases
ATGCGTCCACCCCGTCTCGACCAGCTCGACGAGCTCGACCGGCAACTCGTCGCGTTGCTGCAAGCAAATGCGCGTGCGAG
CGTTGCCGATCTCGCGCGGCAGCTCGACGTCGCGCGCACGACCGTCGTCGCGCGCATTGCGCGGCTCGAACGCACGAACG
TGATCGCGGGCTACAGCGTGCGGCTCGGCCAGGACGTACTCGATGCGAGCATCTATGCGTACGTCGGCATCATCCTCACG
CCGAAGTTCGGCAAGGACGTGCTGCGCAAGCTCGATCGCATGCCGGAAGTGCAACTGCTATGCGCGGTGAGCGGCGAATA
CGACTACGTCGCGTGGCTGCGCGCCGATTCGCCGGAACGGCTCAACGATCTGCTCGACCAGATCGGCACGCTCGAGGGCG
TCGAACGCACGACGACGTCGATCATCCTGTCGCGCAAGATCGATCGCGGGACCATCGGCGGCTGA

Upstream 100 bases:

>100_bases
TTGAAAGGTAGACGCGCGCGAGGCGTTCGGACGCGCCGGCGTTCGCGCTATCATCGCGGCACGTTCCACTTCGCCGGCGC
CCGGCGCCGCGCACAGTCTC

Downstream 100 bases:

>100_bases
GCGGCCGGTGAGCCGCAAGCCGCGCGTATCGGGCGCGTTGTCGTCCGGTTCGTCGCGCCGCGCGACGCGCGACGCGAACG
CGCGTCCATCGTTTCCGCCT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MRPPRLDQLDELDRQLVALLQANARASVADLARQLDVARTTVVARIARLERTNVIAGYSVRLGQDVLDASIYAYVGIILT
PKFGKDVLRKLDRMPEVQLLCAVSGEYDYVAWLRADSPERLNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG

Sequences:

>Translated_154_residues
MRPPRLDQLDELDRQLVALLQANARASVADLARQLDVARTTVVARIARLERTNVIAGYSVRLGQDVLDASIYAYVGIILT
PKFGKDVLRKLDRMPEVQLLCAVSGEYDYVAWLRADSPERLNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG
>Mature_154_residues
MRPPRLDQLDELDRQLVALLQANARASVADLARQLDVARTTVVARIARLERTNVIAGYSVRLGQDVLDASIYAYVGIILT
PKFGKDVLRKLDRMPEVQLLCAVSGEYDYVAWLRADSPERLNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=141, Percent_Identity=30.4964539007092, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790182, Length=145, Percent_Identity=29.6551724137931, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17106; Mature: 17106

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPRLDQLDELDRQLVALLQANARASVADLARQLDVARTTVVARIARLERTNVIAGYSV
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCHH
RLGQDVLDASIYAYVGIILTPKFGKDVLRKLDRMPEVQLLCAVSGEYDYVAWLRADSPER
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCHHH
LNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRPPRLDQLDELDRQLVALLQANARASVADLARQLDVARTTVVARIARLERTNVIAGYSV
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCHH
RLGQDVLDASIYAYVGIILTPKFGKDVLRKLDRMPEVQLLCAVSGEYDYVAWLRADSPER
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCHHH
LNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA