Click here to switch to the map view.

The map label for this gene is engA [H]

Identifier: 161524640

GI number: 161524640

Start: 1613462

End: 1614799

Strand: Direct

Name: engA [H]

Synonym: Bmul_1467

Alternate gene names: 161524640

Gene position: 1613462-1614799 (Clockwise)

Preceding gene: 161524639

Following gene: 161524641

Centisome position: 46.79

GC content: 65.25

Gene sequence:

>1338_bases
ATGAAACCGGTCATTGCCCTCGTTGGGCGCCCCAATGTGGGGAAATCCACGCTGTTCAACCGGCTCACGCGCTCGCGCGA
TGCGCTGGTGGCCGACTTGCCGGGCCTCACGCGCGATCGCCATTACGGCGAAGGACGCGTCGGCGCGCGGCCGTATCTCG
TCGTCGACACGGGCGGCTTCGAGCCCGTCGCGAAGGACGGGATCCTGCACGAGATGGCGCGTCAGACGCGGCAGGCCGTC
GAGGAAGCCGACGTCGTCGTGTTCATCGTCGACGGCCGCAACGGCCTCGCGCCGCAGGACAAGTCGATCGCCGACTATCT
GCGCAAGACGGGCCGGCCGATTTTCCTCGTCGTCAACAAGGCCGAGGGGATGAAGTACACGGCGGTCGCGACCGACTTCT
ACGAACTCGGGCTCGGCGATCCGCGCGCGATCTCGGCCGCGCACGGCGACGGCGTGACCGACATGATCAACGAGGCGCTG
GAGGTCGCGTACGCCGACCAGCCGGAAGAAGAGGACGACAACGATCCGTCGCGCGGCATCAAGATCGCGATCGTCGGCCG
GCCGAACGTCGGCAAGTCGACGCTCGTGAACGCGCTGATCGGCGAGGACCGCGTGATCGCGTTCGACATGCCGGGCACGA
CGCGCGATTCGATCTACGTCGACTTCGAGCGTAACGGCAAGAAATACACGCTGATCGATACGGCCGGCCTGCGTCGCAGC
GGCAAGGTGTTCGAGGCGATCGAGAAGTTCTCGGTCGTGAAGACGCTGCAGTCGATTTCCGACGCGAACGTCGTCATTCT
TCTGCTGGATGCGCAGCAGGACATTTCCGATCAGGACGCGCATATCGCCGGCTTCGTCGTCGAGCAGGGCCGCGCGCTCG
TGATCGGTGTGAACAAATGGGACGGCCTCGACGAGCACGCGCGCGAGCGCGCGAAAGCGGATTTGACCCGCAAGCTGAAA
TTCCTCGACTTCGCCAAGTCGCACTTCATTTCGGCCGCGAAGAAAACGGGCATCGGCGCGCTGATGCGCTCGGTCGACGA
TGCGTATGCGGCCGCCATGGCGAAGCTGCCGACGCCGAAGCTCACGCGCGCGCTGATCGAGGCCGTGGAATTCCAGCAGC
CGCGCCGCCGCGGCCCCGTGCGGCCCAAGCTGCGCTACGCGCACCAGGGCGGCCAGAATCCGCCGATCATCGTGATCCAC
GGCAACGCGCTCGACGCCGTGACGGAAACGTACAAGCGTTACCTGGAGAACCGTTTCCGCGAAACTTTCTCCCTGACCGG
CACTCCATTGCGCATAGAGTTCCGTTCGTCGACCAACCCGTACGCGGACAAGGGCTGA

Upstream 100 bases:

>100_bases
GCGCGCATCCGGCGCGGCGCGAATTCGTGATATTTTCATTCAGCGCAGCCGCCCGCAGCAGCGGGCCTCCCGCTGCTGCG
CTTCACCGTAGACAACACAG

Downstream 100 bases:

>100_bases
AGCACGCCTGATACCCGCTTCCGGCAACGGATCGGCCGCATGGCCGACGCCGGGCGCGGCAGGCAAAATCAGCTATAGTG
TAGCGATTGGCGCCGGATCT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGARPYLVVDTGGFEPVAKDGILHEMARQTRQAV
EEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEAL
EVAYADQPEEEDDNDPSRGIKIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRS
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKWDGLDEHARERAKADLTRKLK
FLDFAKSHFISAAKKTGIGALMRSVDDAYAAAMAKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIH
GNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSTNPYADKG

Sequences:

>Translated_445_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGARPYLVVDTGGFEPVAKDGILHEMARQTRQAV
EEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEAL
EVAYADQPEEEDDNDPSRGIKIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRS
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKWDGLDEHARERAKADLTRKLK
FLDFAKSHFISAAKKTGIGALMRSVDDAYAAAMAKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIH
GNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSTNPYADKG
>Mature_445_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGARPYLVVDTGGFEPVAKDGILHEMARQTRQAV
EEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEAL
EVAYADQPEEEDDNDPSRGIKIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRS
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKWDGLDEHARERAKADLTRKLK
FLDFAKSHFISAAKKTGIGALMRSVDDAYAAAMAKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIH
GNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSTNPYADKG

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=51.9230769230769, Blast_Score=479, Evalue=1e-136,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=39.1304347826087, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788919, Length=124, Percent_Identity=33.8709677419355, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=95, Percent_Identity=37.8947368421053, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=180, Percent_Identity=31.6666666666667, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48971; Mature: 48971

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGARPYLVVDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVAKDGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNK
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEC
AEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEALEVAYADQPEEEDDNDPSRGI
CCCCEEEEEEHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
KIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRS
EEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCC
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKW
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCCC
DGLDEHARERAKADLTRKLKFLDFAKSHFISAAKKTGIGALMRSVDDAYAAAMAKLPTPK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIHGNALDAVTETYKRYLENRFR
HHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
ETFSLTGTPLRIEFRSSTNPYADKG
HHHCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGARPYLVVDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVAKDGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNK
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEC
AEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEALEVAYADQPEEEDDNDPSRGI
CCCCEEEEEEHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
KIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRS
EEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCC
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKW
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCCC
DGLDEHARERAKADLTRKLKFLDFAKSHFISAAKKTGIGALMRSVDDAYAAAMAKLPTPK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIHGNALDAVTETYKRYLENRFR
HHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
ETFSLTGTPLRIEFRSSTNPYADKG
HHHCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA