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The map label for this gene is insK [H]

Identifier: 161524512

GI number: 161524512

Start: 1471120

End: 1471956

Strand: Direct

Name: insK [H]

Synonym: Bmul_1339

Alternate gene names: 161524512

Gene position: 1471120-1471956 (Clockwise)

Preceding gene: 161524511

Following gene: 161524517

Centisome position: 42.66

GC content: 57.59

Gene sequence:

>837_bases
GTGCGCGAGCTCAGACAGCATCATCCGGTAGCAGCGCTTCTGAAGGTGGCCGGTTTGGCGCGCAGCACGTTCTATTACCA
GTTGGGGACGCTCAATGCCGACGATCGCCACGCTGATCTGAAGGCAAAGATCCGGACGGTGTTCGAACATCACAAGGGAC
GCTACGGCTATCGACGCGTGACGGCTGCCATCCGGCAAGCCGGGCATCTCGTCAACCACAAGGCCGTGCAGCGGCTGATG
CAGCAATTGCAACTGAAGTCCCTGGTGCGCCCGAAGAAATATCGCTCTTGGCGAGGTGAGATCGGGCAGGCCGCACCCAA
TCTGCTGCAACGCCAGTTCAGTGCCACGCAGGCCAACCAGAAGTGGGTAACGGACGTGACGGAGTTCAACGTCGGCGGGC
AGAAGTTGTATCTATCGCCGGTGATGGATCTATACAACGGCGAGATCGTGGCTTACCAGATGGATCAACGTCCAAGCTTC
GAACTGGTCAGCGGCATGCTGAAGAAGGCGCTGGCCAAGCTGCGGCGCAAGGACAAACCGTTATTACATTCGGATCAAGG
CTGGCAATACCGGATGCCGGCGTATCGCCGGGAACTGAAGAAGCGCAAGCTGACCCAGAGCATGTCGCGCAAGGGCAATT
GCCTGGACAACGCCGCGATGGAAAGCTTCTTCGGCACGCTCAAGTCTGAGTGCTACAACGGGCATTGTTTCACTTGTGTA
GAGCAATTGCGCGACACGCTGGACCACTACATCCACTACTACAACCACGAACGCATCAAGCTCAAATTGAAAGGGCTGAG
TCCCGTGCAATACAGAACTCAGCCCTTGGGCGCCTAG

Upstream 100 bases:

>100_bases
TCAAGGAAAACGAGTATCTGCGTGCGGAGGTGGCGTACCTAAAAAAGCTCGATGCGCTGCTGGCCAAGAAGCAGGCAGCG
CAAAAGAAAAAACGCAAATA

Downstream 100 bases:

>100_bases
TGTTTAACCGTCCAACTTTGCGGGGTCAGTTCAGTCTCCGACCGCAGCGCTTTTTCGTTATCCGCGCATCTTGCTCGCGA
TCGCCGCCGCCGCTAATCCC

Product: integrase catalytic region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MRELRQHHPVAALLKVAGLARSTFYYQLGTLNADDRHADLKAKIRTVFEHHKGRYGYRRVTAAIRQAGHLVNHKAVQRLM
QQLQLKSLVRPKKYRSWRGEIGQAAPNLLQRQFSATQANQKWVTDVTEFNVGGQKLYLSPVMDLYNGEIVAYQMDQRPSF
ELVSGMLKKALAKLRRKDKPLLHSDQGWQYRMPAYRRELKKRKLTQSMSRKGNCLDNAAMESFFGTLKSECYNGHCFTCV
EQLRDTLDHYIHYYNHERIKLKLKGLSPVQYRTQPLGA

Sequences:

>Translated_278_residues
MRELRQHHPVAALLKVAGLARSTFYYQLGTLNADDRHADLKAKIRTVFEHHKGRYGYRRVTAAIRQAGHLVNHKAVQRLM
QQLQLKSLVRPKKYRSWRGEIGQAAPNLLQRQFSATQANQKWVTDVTEFNVGGQKLYLSPVMDLYNGEIVAYQMDQRPSF
ELVSGMLKKALAKLRRKDKPLLHSDQGWQYRMPAYRRELKKRKLTQSMSRKGNCLDNAAMESFFGTLKSECYNGHCFTCV
EQLRDTLDHYIHYYNHERIKLKLKGLSPVQYRTQPLGA
>Mature_278_residues
MRELRQHHPVAALLKVAGLARSTFYYQLGTLNADDRHADLKAKIRTVFEHHKGRYGYRRVTAAIRQAGHLVNHKAVQRLM
QQLQLKSLVRPKKYRSWRGEIGQAAPNLLQRQFSATQANQKWVTDVTEFNVGGQKLYLSPVMDLYNGEIVAYQMDQRPSF
ELVSGMLKKALAKLRRKDKPLLHSDQGWQYRMPAYRRELKKRKLTQSMSRKGNCLDNAAMESFFGTLKSECYNGHCFTCV
EQLRDTLDHYIHYYNHERIKLKLKGLSPVQYRTQPLGA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=234, Percent_Identity=29.4871794871795, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1789981, Length=274, Percent_Identity=55.1094890510949, Blast_Score=334, Evalue=3e-93,
Organism=Escherichia coli, GI1788405, Length=277, Percent_Identity=32.8519855595668, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787263, Length=277, Percent_Identity=32.8519855595668, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786753, Length=277, Percent_Identity=32.8519855595668, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786570, Length=277, Percent_Identity=32.8519855595668, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786490, Length=277, Percent_Identity=32.8519855595668, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32334; Mature: 32334

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS50994 INTEGRASE ; PS00028 ZINC_FINGER_C2H2_1 ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELRQHHPVAALLKVAGLARSTFYYQLGTLNADDRHADLKAKIRTVFEHHKGRYGYRRV
CCCHHHHCHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
TAAIRQAGHLVNHKAVQRLMQQLQLKSLVRPKKYRSWRGEIGQAAPNLLQRQFSATQANQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KWVTDVTEFNVGGQKLYLSPVMDLYNGEIVAYQMDQRPSFELVSGMLKKALAKLRRKDKP
HHHHHHHHCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
LLHSDQGWQYRMPAYRRELKKRKLTQSMSRKGNCLDNAAMESFFGTLKSECYNGHCFTCV
CCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
EQLRDTLDHYIHYYNHERIKLKLKGLSPVQYRTQPLGA
HHHHHHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCC
>Mature Secondary Structure
MRELRQHHPVAALLKVAGLARSTFYYQLGTLNADDRHADLKAKIRTVFEHHKGRYGYRRV
CCCHHHHCHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
TAAIRQAGHLVNHKAVQRLMQQLQLKSLVRPKKYRSWRGEIGQAAPNLLQRQFSATQANQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KWVTDVTEFNVGGQKLYLSPVMDLYNGEIVAYQMDQRPSFELVSGMLKKALAKLRRKDKP
HHHHHHHHCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
LLHSDQGWQYRMPAYRRELKKRKLTQSMSRKGNCLDNAAMESFFGTLKSECYNGHCFTCV
CCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
EQLRDTLDHYIHYYNHERIKLKLKGLSPVQYRTQPLGA
HHHHHHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]