Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 161523984

GI number: 161523984

Start: 881926

End: 883110

Strand: Reverse

Name: argD [H]

Synonym: Bmul_0804

Alternate gene names: 161523984

Gene position: 883110-881926 (Counterclockwise)

Preceding gene: 161523985

Following gene: 161523983

Centisome position: 25.61

GC content: 65.57

Gene sequence:

>1185_bases
ATGCCCCTGAACGATTACCCGATCGACTCGCTGATGTACATCACGAACCGCCCCGACATCGTGTTTACGCACGGCAAGGG
GTCCTGGCTCTACGATCACACGGGCAAGCGCTATCTCGACTTCATCCAGGGCTGGGCCGTCAACAGCCTCGGGCACTGCA
ACGAAGGGATCGTCGAAGCGCTGAAGTCGCAGGCCGAGAAGCTGCTGAATCCGTCGCCGGCGTTCTACAACGAGCCGATG
GCGAAGCTCGCCGATCTGCTCACGCAGCACAGTGTGTTCGACAAGGTGTTCTTCACGAACAGCGGCGCCGAAGCGAACGA
AGGCGCGATCAAGCTCGCGCGCAAGTGGGGCCGCAAGTTCCGCAACGGCGCGTACGAGATCATCACGTTCGATCACAGCT
TCCACGGCCGCACGCTCGCGACGATGTCGGCGAGCGGCAAGCCGGGCTGGGACACGCTCTACGCGCCGCAGGTGCCCGGC
TTCCCGAAGGCCGAGCTGAACAACATCGAATCGGTCGAGAAGCTGATCAACGAGAAGACGGTCGCGGTGATGCTCGAGCC
GATCCAGGGCGAAGGCGGCGTGATTCCGGCGACGCGCGAGTTCATGCGCGCGCTGCGCGAGCTGACGCGCCAGCACAACC
TGCTGCTGATCGTCGACGAAGTGCAAAGCGGGTGCGGCCGCGCGGGCACGCTGTTCGCCTACGAGCTGTCGGGCATCGAG
CCGGACATCATGACGCTCGCCAAGGGCATCGGCGGCGGCGTGCCGCTCGGCGCGCTGCTGTCGAAGGCCGACGTCGCGGT
ATTCGAAGCCGGCGATCAGGGCGGCACCTACAACGGCAATCCGCTGATGACGGCGGTCGGCCATTCGGTGATCTCGCAAC
TGGTCGCGCCGGGCTTCCTCGAGGGCGTGCGTGCGCGCAGCGAATACCTGAAGCGCAAGCTGATCGAGCTGTCGGAGGAG
CGCGGCTTCGAAGGCGAACGCGGCGAAGGGCTGCTGCGCGCGCTGCTGCTCGGCAAGGACATCGGCCCGCAGATCGTCGA
GAAGGCGCGCGACATGCAGCCCGACGGGCTGCTGCTGAACGCCGCGCGCCCGAACCTGCTGCGTTTCATGCCCGCGCTGA
ACGTGACGACCGAGGAAATCGACCAGATGATGGCGATGCTGCGGTCGGTGCTCGACACGCTCTGA

Upstream 100 bases:

>100_bases
CTTCACCGGTTACGCACAAGCTGTTCGATCCACCAGCCACGGCATTCCGTGGCTTTTTTATTGCCCGTTTCCGTTTCCAC
GTCCGCCGGAGTCTGCTGCC

Downstream 100 bases:

>100_bases
GGAGAACCCGCCGATGGATGCCGCCGCCGATGCCGTCGTTATCCGCCCGTTCGACCGCGCCGACACCGATGCCGTGCTCG
CGGTGTGGCGCGACGCGTTT

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNEGIVEALKSQAEKLLNPSPAFYNEPM
AKLADLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTLYAPQVPG
FPKAELNNIESVEKLINEKTVAVMLEPIQGEGGVIPATREFMRALRELTRQHNLLLIVDEVQSGCGRAGTLFAYELSGIE
PDIMTLAKGIGGGVPLGALLSKADVAVFEAGDQGGTYNGNPLMTAVGHSVISQLVAPGFLEGVRARSEYLKRKLIELSEE
RGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTTEEIDQMMAMLRSVLDTL

Sequences:

>Translated_394_residues
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNEGIVEALKSQAEKLLNPSPAFYNEPM
AKLADLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTLYAPQVPG
FPKAELNNIESVEKLINEKTVAVMLEPIQGEGGVIPATREFMRALRELTRQHNLLLIVDEVQSGCGRAGTLFAYELSGIE
PDIMTLAKGIGGGVPLGALLSKADVAVFEAGDQGGTYNGNPLMTAVGHSVISQLVAPGFLEGVRARSEYLKRKLIELSEE
RGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTTEEIDQMMAMLRSVLDTL
>Mature_393_residues
PLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNEGIVEALKSQAEKLLNPSPAFYNEPMA
KLADLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKFRNGAYEIITFDHSFHGRTLATMSASGKPGWDTLYAPQVPGF
PKAELNNIESVEKLINEKTVAVMLEPIQGEGGVIPATREFMRALRELTRQHNLLLIVDEVQSGCGRAGTLFAYELSGIEP
DIMTLAKGIGGGVPLGALLSKADVAVFEAGDQGGTYNGNPLMTAVGHSVISQLVAPGFLEGVRARSEYLKRKLIELSEER
GFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLNAARPNLLRFMPALNVTTEEIDQMMAMLRSVLDTL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=31.7460317460317, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=28.1030444964871, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=30.5369127516779, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=28.3653846153846, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=26.4423076923077, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=27.6442307692308, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=28.4974093264249, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI188536080, Length=290, Percent_Identity=26.2068965517241, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI38679950, Length=290, Percent_Identity=26.2068965517241, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI38679946, Length=290, Percent_Identity=26.2068965517241, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1788044, Length=360, Percent_Identity=44.4444444444444, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1789759, Length=369, Percent_Identity=41.4634146341463, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=32.6633165829146, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=31.2020460358056, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1787560, Length=398, Percent_Identity=31.4070351758794, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786349, Length=332, Percent_Identity=31.6265060240964, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786991, Length=311, Percent_Identity=29.5819935691318, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=32.3684210526316, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI32564660, Length=417, Percent_Identity=28.7769784172662, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI25144274, Length=270, Percent_Identity=32.962962962963, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=416, Percent_Identity=28.6057692307692, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71981843, Length=163, Percent_Identity=30.6748466257669, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=432, Percent_Identity=24.7685185185185, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=33.6658354114713, Blast_Score=212, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6323470, Length=397, Percent_Identity=31.7380352644836, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321456, Length=424, Percent_Identity=25, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=462, Percent_Identity=24.8917748917749, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=33.3333333333333, Blast_Score=215, Evalue=5e-56,
Organism=Drosophila melanogaster, GI161085790, Length=415, Percent_Identity=27.4698795180723, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=26.9320843091335, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28574759, Length=414, Percent_Identity=27.536231884058, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI281366494, Length=423, Percent_Identity=24.113475177305, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24667139, Length=423, Percent_Identity=24.113475177305, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24667143, Length=423, Percent_Identity=24.113475177305, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43216; Mature: 43085

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNEGIVEA
CCCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHH
LKSQAEKLLNPSPAFYNEPMAKLADLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKF
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHH
RNGAYEIITFDHSFHGRTLATMSASGKPGWDTLYAPQVPGFPKAELNNIESVEKLINEKT
CCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHCCCE
VAVMLEPIQGEGGVIPATREFMRALRELTRQHNLLLIVDEVQSGCGRAGTLFAYELSGIE
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCEEEEEEECCCC
PDIMTLAKGIGGGVPLGALLSKADVAVFEAGDQGGTYNGNPLMTAVGHSVISQLVAPGFL
HHHHHHHHHCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
EGVRARSEYLKRKLIELSEERGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLN
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
AARPNLLRFMPALNVTTEEIDQMMAMLRSVLDTL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLNDYPIDSLMYITNRPDIVFTHGKGSWLYDHTGKRYLDFIQGWAVNSLGHCNEGIVEA
CCCCCCCCCEEEEECCCCEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHH
LKSQAEKLLNPSPAFYNEPMAKLADLLTQHSVFDKVFFTNSGAEANEGAIKLARKWGRKF
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHH
RNGAYEIITFDHSFHGRTLATMSASGKPGWDTLYAPQVPGFPKAELNNIESVEKLINEKT
CCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHCCCE
VAVMLEPIQGEGGVIPATREFMRALRELTRQHNLLLIVDEVQSGCGRAGTLFAYELSGIE
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCEEEEEEECCCC
PDIMTLAKGIGGGVPLGALLSKADVAVFEAGDQGGTYNGNPLMTAVGHSVISQLVAPGFL
HHHHHHHHHCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
EGVRARSEYLKRKLIELSEERGFEGERGEGLLRALLLGKDIGPQIVEKARDMQPDGLLLN
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEE
AARPNLLRFMPALNVTTEEIDQMMAMLRSVLDTL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]