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The map label for this gene is nadB1 [H]

Identifier: 161523971

GI number: 161523971

Start: 870890

End: 872476

Strand: Reverse

Name: nadB1 [H]

Synonym: Bmul_0791

Alternate gene names: 161523971

Gene position: 872476-870890 (Counterclockwise)

Preceding gene: 161523972

Following gene: 161523964

Centisome position: 25.3

GC content: 67.55

Gene sequence:

>1587_bases
ATGAAATTCGACGTGGCGATCGTCGGCAGCGGCCTGGCAGGGCTGTCGGTCGCACTCAACCTGGCCAGCACGCGACGCGT
CGCGCTGATCGCGAAGCGTTCGATGATGGAAGGCGCGAGCGATAACGCACAAGGCGGCATCGCCGCTGTCCTCGATTCGG
CGGACAGCATCGAAAACCACGTCGACGATACGCTCGTCGCAGGCGGCGGCCTGTGCGACGAAGGCGCGACGCGCTACATC
GTCGAGCACGGCCGCGAGGCGATCGAATGGCTGATCTCGCAGGGCGTGCCGTTCACGAAGGACGACGCGGCCGAACTCGG
CTTTCATTTGACGCGCGAAGGCGGCCACAGTCATCGCCGCATCATCCACGCGGCCGACGCGACCGGTCATGCGGTGCTCG
CGACGCTGTCGGAGCGCGCGCGCCGGCATCCGAACATCACGTTCTTCGAAAACCATCACGCGATCGACCTGATCACGTCG
GACCGGCTCGGCCTGCCCGGCCGCCGCTGTCACGGCCTGTACGCGCTCGACGTCGAGCACGACCGCACGATCACGATCGA
GGCGCCGCACACAGTGCTCGCGACAGGCGGCGCCGGCAAGGTCTACCTGTACACGACGAACCCCGACACCGCGACCGGCG
ACGGCATCGCGATGGCGTGGCGCGCAGGCTGCCGCGTCGCGAACATGGAATTCATCCAGTTCCATCCGACCTGCCTGTTC
CATCCGTACGCGAAATCGTTCCTGATCTCCGAAGCCGTGCGCGGCGAAGGCGGCCTGCTGAAGCTGCCGGACGGCACGCG
CTTCATGCCCGCGCACGATCCGCGTGCGGAACTCGCGCCGCGCGACATCGTCGCGCGCGCGATCGACTTCGAGATCAAGA
AGCGCGGGATCGACTGCGTCTATCTCGACATCAGCCACCAGCCCGAAGCGTTCCTGCGCGAGCACTTCCCGACGATCCAC
GCGCGCTGCCTCGAATTCGGCATCGACATCGCGAAGGAGCCGATTCCGGTCGTGCCGGCCGCGCACTACACGTGCGGCGG
CGTCGTGACCGACCTCGCCGGACGCACCGATCTGGCCGGCCTGTATGCGGTCGGCGAAACGTCGTACACGGGCCTGCACG
GCGCGAACCGGCTCGCGAGCAATTCGCTGCTCGAATGCCTCGTGATCGGCCGTGCGGCGGCCGGGGCGATCGAAGCGGCC
GGCTTCGACGTCGAAGCGACGGGCCCGCTGCCCGCATGGGACGAGAGCCGCGTGTCCGATGCCGACGAAGAAGTCGTCGT
CGCGCACAACTGGGACGAGCTGCGCCGCCTGATGTGGAACTACGTCGGCATCGTGCGTACCGACAAACGCCTCGAGCGCG
CGAAGCACCGGCTGTCGCTGCTGCGCGACGAGATCCACGAGTACTACGCGAACTTCCGCGTGACGCGCGATCTGCTCGAA
CTGCGCAATCTCGTCGACGTCGCGACGCTGATCGTGAAGAGTGCGCAGTCGCGCCGCGAAAGCCGCGGGCTGCACTACAG
CCGCGACTGGCCGAACACGCTGCCGAAGGCGCTGCCGAGCGTGCTGCAGCCGCGTTCGCGTCGCTGA

Upstream 100 bases:

>100_bases
TGCGCGTACGCAGCTTCGCCCGACGCGGTATGCTCTCCCCTTTCCCGCGGCACGGCCGCCGGAACGCACGAGCTTCAAAG
CACAACGATGGAGATGCAGC

Downstream 100 bases:

>100_bases
GCGACGCACGCGCTGACCGGAACGAGAAAGGCCGCCGGCGCATACGCACCGGCGGCCTTTTCATTGCGTTGCCGCGCGTC
GTGCGATCAGGCGACGATGC

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO 1; Quinolinate synthase B 1 [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIENHVDDTLVAGGGLCDEGATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARRHPNITFFENHHAIDLITS
DRLGLPGRRCHGLYALDVEHDRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVANMEFIQFHPTCLF
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFPTIH
ARCLEFGIDIAKEPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETSYTGLHGANRLASNSLLECLVIGRAAAGAIEAA
GFDVEATGPLPAWDESRVSDADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
LRNLVDVATLIVKSAQSRRESRGLHYSRDWPNTLPKALPSVLQPRSRR

Sequences:

>Translated_528_residues
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIENHVDDTLVAGGGLCDEGATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARRHPNITFFENHHAIDLITS
DRLGLPGRRCHGLYALDVEHDRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVANMEFIQFHPTCLF
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFPTIH
ARCLEFGIDIAKEPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETSYTGLHGANRLASNSLLECLVIGRAAAGAIEAA
GFDVEATGPLPAWDESRVSDADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
LRNLVDVATLIVKSAQSRRESRGLHYSRDWPNTLPKALPSVLQPRSRR
>Mature_528_residues
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIENHVDDTLVAGGGLCDEGATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARRHPNITFFENHHAIDLITS
DRLGLPGRRCHGLYALDVEHDRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVANMEFIQFHPTCLF
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFPTIH
ARCLEFGIDIAKEPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETSYTGLHGANRLASNSLLECLVIGRAAAGAIEAA
GFDVEATGPLPAWDESRVSDADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
LRNLVDVATLIVKSAQSRRESRGLHYSRDWPNTLPKALPSVLQPRSRR

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=506, Percent_Identity=34.9802371541502, Blast_Score=243, Evalue=3e-64,
Organism=Escherichia coli, GI1788928, Length=524, Percent_Identity=59.5419847328244, Blast_Score=636, Evalue=0.0,
Organism=Escherichia coli, GI1790597, Length=528, Percent_Identity=35.9848484848485, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI1786942, Length=554, Percent_Identity=34.2960288808664, Blast_Score=223, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17550100, Length=531, Percent_Identity=34.4632768361582, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17505833, Length=529, Percent_Identity=32.703213610586, Blast_Score=233, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI71986328, Length=464, Percent_Identity=28.2327586206897, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322701, Length=526, Percent_Identity=33.4600760456274, Blast_Score=235, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6322416, Length=514, Percent_Identity=33.4630350194552, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6322511, Length=480, Percent_Identity=28.125, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320788, Length=480, Percent_Identity=28.125, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17137288, Length=541, Percent_Identity=34.7504621072089, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24655642, Length=541, Percent_Identity=34.7504621072089, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24655647, Length=541, Percent_Identity=34.7504621072089, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24663005, Length=550, Percent_Identity=32.3636363636364, Blast_Score=222, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 57887; Mature: 57887

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIENH
CEEEEEEECCCCCHHHHHEEHHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHH
VDDTLVAGGGLCDEGATRYIVEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRR
HCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEECCCCCCCEE
IIHAADATGHAVLATLSERARRHPNITFFENHHAIDLITSDRLGLPGRRCHGLYALDVEH
EEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCHHCCEEEEEECC
DRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVANMEFIQFHPTCLF
CCEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCEEEHHHCCCEEECEEEEEECCCEEE
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCV
CHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
YLDISHQPEAFLREHFPTIHARCLEFGIDIAKEPIPVVPAAHYTCGGVVTDLAGRTDLAG
EEECCCCCHHHHHHHCHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCE
LYAVGETSYTGLHGANRLASNSLLECLVIGRAAAGAIEAAGFDVEATGPLPAWDESRVSD
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEECCCCCCCCCCCCCCC
ADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
CCCCEEEEECHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNLVDVATLIVKSAQSRRESRGLHYSRDWPNTLPKALPSVLQPRSRR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIENH
CEEEEEEECCCCCHHHHHEEHHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHH
VDDTLVAGGGLCDEGATRYIVEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRR
HCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEECCCCCCCEE
IIHAADATGHAVLATLSERARRHPNITFFENHHAIDLITSDRLGLPGRRCHGLYALDVEH
EEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCHHCCEEEEEECC
DRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVANMEFIQFHPTCLF
CCEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCEEEHHHCCCEEECEEEEEECCCEEE
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCV
CHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
YLDISHQPEAFLREHFPTIHARCLEFGIDIAKEPIPVVPAAHYTCGGVVTDLAGRTDLAG
EEECCCCCHHHHHHHCHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCE
LYAVGETSYTGLHGANRLASNSLLECLVIGRAAAGAIEAAGFDVEATGPLPAWDESRVSD
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEECCCCCCCCCCCCCCC
ADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
CCCCEEEEECHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNLVDVATLIVKSAQSRRESRGLHYSRDWPNTLPKALPSVLQPRSRR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]