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The map label for this gene is btr [H]

Identifier: 161523935

GI number: 161523935

Start: 827453

End: 828160

Strand: Reverse

Name: btr [H]

Synonym: Bmul_0755

Alternate gene names: 161523935

Gene position: 828160-827453 (Counterclockwise)

Preceding gene: 161523938

Following gene: 161523934

Centisome position: 24.02

GC content: 71.75

Gene sequence:

>708_bases
ATGCCTGCCTCGCTCGCCCCGTACCTGCCGCAGCTCGACGCGCACCCGTGGTTCGCCGCGCTGCCGCCGGCGCTGCGCGC
GCAACTGCTCGCCGCCGCCGAACTGCGCCGCCTGCCGGCCGGACACGCGCTGTTCCGGCGCGGCGATCCGCCGTGCGGGC
TGTACGCGGTGCTGGACGGCTCGCTGACGATCGGCGCGGTGGACGCGCACGGCAAGGAAGCGCTGCTGACGGTGGCGGAT
CCCGTCACGTGGTTCGGCGAAATCGCGCTGTTCGACGGACAGCCGCGCACGCACGACGCGGTCGCGCTCGACGACGCGCT
GCTGCTGCACGTGCCGCAGCCCGCGCTGCTCGCGATCCTCGACGCGACGCCGCAATACTGGCGGCAGTTCGCGCTGCTGA
TGGCGCAGAAGCTGCGCCTGAGCTTCCTGACCGTCGAATCGATGAGCGTGATGTCGGCTGCGCAGCGTCTCGCCGCGCGT
CTGCTGATGATCGCCGACGGCTACGGCGGGATCAGCGCGGGCCGCACGCGCGTGCGGCTGTCGCAGGAAAAGCTCGCGGC
GATGCTGTCGCTCACGCGCCAGACGACCAATCAGCTGCTGAATGCACTGCAGGCGGACGGCGTCGTGCGACTGCATGTCG
GCGAGATCGAAATCGTCGACGTCGACGCGCTGCGCCGCGCGAGCGGGCTGCATGACGGGCCGCGCTGA

Upstream 100 bases:

>100_bases
TGGTCTTCGAGCGTCTTCATCGCGTCTCCTGAAACGGTCGTTGGCGCTATGATGCCCGTCACGCCTGCGTCCCTCTGTCA
GCTACCCGACATCGCGCCCC

Downstream 100 bases:

>100_bases
GCGCGCCGCCGTCCCCGCCGCGCGCGCATTGCGCTATCGTGGCGGCTCGTCCGATCGGCCGACCGCCGTTCGCGTCCCAT
TCGTCTTCGTGAGCCGCCGG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MPASLAPYLPQLDAHPWFAALPPALRAQLLAAAELRRLPAGHALFRRGDPPCGLYAVLDGSLTIGAVDAHGKEALLTVAD
PVTWFGEIALFDGQPRTHDAVALDDALLLHVPQPALLAILDATPQYWRQFALLMAQKLRLSFLTVESMSVMSAAQRLAAR
LLMIADGYGGISAGRTRVRLSQEKLAAMLSLTRQTTNQLLNALQADGVVRLHVGEIEIVDVDALRRASGLHDGPR

Sequences:

>Translated_235_residues
MPASLAPYLPQLDAHPWFAALPPALRAQLLAAAELRRLPAGHALFRRGDPPCGLYAVLDGSLTIGAVDAHGKEALLTVAD
PVTWFGEIALFDGQPRTHDAVALDDALLLHVPQPALLAILDATPQYWRQFALLMAQKLRLSFLTVESMSVMSAAQRLAAR
LLMIADGYGGISAGRTRVRLSQEKLAAMLSLTRQTTNQLLNALQADGVVRLHVGEIEIVDVDALRRASGLHDGPR
>Mature_234_residues
PASLAPYLPQLDAHPWFAALPPALRAQLLAAAELRRLPAGHALFRRGDPPCGLYAVLDGSLTIGAVDAHGKEALLTVADP
VTWFGEIALFDGQPRTHDAVALDDALLLHVPQPALLAILDATPQYWRQFALLMAQKLRLSFLTVESMSVMSAAQRLAARL
LMIADGYGGISAGRTRVRLSQEKLAAMLSLTRQTTNQLLNALQADGVVRLHVGEIEIVDVDALRRASGLHDGPR

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25327; Mature: 25196

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASLAPYLPQLDAHPWFAALPPALRAQLLAAAELRRLPAGHALFRRGDPPCGLYAVLDG
CCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEECC
SLTIGAVDAHGKEALLTVADPVTWFGEIALFDGQPRTHDAVALDDALLLHVPQPALLAIL
CEEEEEECCCCCEEEEEECCCHHHHEEEEEECCCCCCCCCEEECCEEEEECCCHHHHHEE
DATPQYWRQFALLMAQKLRLSFLTVESMSVMSAAQRLAARLLMIADGYGGISAGRTRVRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEE
SQEKLAAMLSLTRQTTNQLLNALQADGVVRLHVGEIEIVDVDALRRASGLHDGPR
CHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PASLAPYLPQLDAHPWFAALPPALRAQLLAAAELRRLPAGHALFRRGDPPCGLYAVLDG
CCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEECC
SLTIGAVDAHGKEALLTVADPVTWFGEIALFDGQPRTHDAVALDDALLLHVPQPALLAIL
CEEEEEECCCCCEEEEEECCCHHHHEEEEEECCCCCCCCCEEECCEEEEECCCHHHHHEE
DATPQYWRQFALLMAQKLRLSFLTVESMSVMSAAQRLAARLLMIADGYGGISAGRTRVRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEE
SQEKLAAMLSLTRQTTNQLLNALQADGVVRLHVGEIEIVDVDALRRASGLHDGPR
CHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]