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The map label for this gene is murB [H]

Identifier: 161523922

GI number: 161523922

Start: 814369

End: 815418

Strand: Direct

Name: murB [H]

Synonym: Bmul_0742

Alternate gene names: 161523922

Gene position: 814369-815418 (Clockwise)

Preceding gene: 161523920

Following gene: 161523924

Centisome position: 23.62

GC content: 71.14

Gene sequence:

>1050_bases
ATGCCGATGCCTCCTGACGAATCCGCCCTGTCGCTGCTCCCCGACCATCCGCTCGCCGCGCACAACACGTTCGGCATCGA
CGCGAGGGCGCGCTATGCCGCGCGCATCACACATCCCGCGCAGTTCGAGGCGCTGCATCGCGACGCGCGCGTCGCGACGC
TGCCGCATCTCGTGCTCGGCGGCGGCAGCAATGTCGTGTTCACGCGCGACTTCGACGGCCTCGTGCTGCTCGATGAAATC
GCCGGGCGCCGCGTCGTGCGCGACGACGACGACGCGTGGTACGTCGAAGCCGGCGGCGGCGAGAACTGGCACGCGTTCGT
CGGCTGGACGCTCGAGCACGGCATGGCGGGCCTCGAGAACCTCGCACTGATCCCGGGCACCGTCGGCGCGGCGCCGATCC
AGAACATCGGCGCGTACGGCCTCGAAATGAACGCGTATTTCGATTCGCTCGTCGCGGTCGAACTCGCGACGGGGCGCAGC
GAGCGTTTCGACGCCGCGCGCTGCGCGTTCGGCTATCGCGACAGCTTCTTCAAGCGCGACGGGCGCGGGCGCTTCGCGAT
CGTATCGGTGACGTTCCGGCTGCCGAAACGCTGGACGCCGCGGCTCGGCTATGCGGACGTGACGCGCGAACTCGAGGCGC
GCGGCATCTCGCCGGACGCGGCGACGCCGCGCGACGTGTTCGATGCGGTCGTCGCGATCCGGCGCGCGAAACTCCCCGAT
CCGCGCGAGCTCGGCAACGCGGGCAGCTTCTTCAAGAATCCGGTGATCGATCGCGCGCAGTTCGATGCGCTGCATGCGCG
CGCGCCGGGCATCGTGTCGTATCCGCAGCCGGACGGCCGCGTGAAGCTCGCGGCGGGCTGGCTGATCGACCGCTGCGGCT
GGAAAGGGCGCGCGCTCGGTGCGGCGGCCGTGCACGACCGGCAGGCGCTCGTGCTCGTCAATCGCGGCGGCGCGACGGGC
GCGGACGTGCTCGCGCTCGCGCGCGCGATCCAGCACGACGTGCGCACGCAGTTCGGCGTCGAGCTCGAGCCCGAGCCGGT
CTGCCTGTAG

Upstream 100 bases:

>100_bases
CGGGCACTCGCTATAATTGCGGACTGTTTGCCATTTTACCGATGCCCTTCCGTTTGCCCAAGGCCGCGCCGTGCGGCCCG
TCGGGCGGACGCGAGCGCGA

Downstream 100 bases:

>100_bases
CGCGGACGGATCCGGCGACTGCGGCGGGCGCACCGGTTTCCCGTGCCGTACAAAACGAAACGCCGATCGGACGATCGGCG
TTTTTCATGCGATGCACGCG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MPMPPDESALSLLPDHPLAAHNTFGIDARARYAARITHPAQFEALHRDARVATLPHLVLGGGSNVVFTRDFDGLVLLDEI
AGRRVVRDDDDAWYVEAGGGENWHAFVGWTLEHGMAGLENLALIPGTVGAAPIQNIGAYGLEMNAYFDSLVAVELATGRS
ERFDAARCAFGYRDSFFKRDGRGRFAIVSVTFRLPKRWTPRLGYADVTRELEARGISPDAATPRDVFDAVVAIRRAKLPD
PRELGNAGSFFKNPVIDRAQFDALHARAPGIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATG
ADVLALARAIQHDVRTQFGVELEPEPVCL

Sequences:

>Translated_349_residues
MPMPPDESALSLLPDHPLAAHNTFGIDARARYAARITHPAQFEALHRDARVATLPHLVLGGGSNVVFTRDFDGLVLLDEI
AGRRVVRDDDDAWYVEAGGGENWHAFVGWTLEHGMAGLENLALIPGTVGAAPIQNIGAYGLEMNAYFDSLVAVELATGRS
ERFDAARCAFGYRDSFFKRDGRGRFAIVSVTFRLPKRWTPRLGYADVTRELEARGISPDAATPRDVFDAVVAIRRAKLPD
PRELGNAGSFFKNPVIDRAQFDALHARAPGIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATG
ADVLALARAIQHDVRTQFGVELEPEPVCL
>Mature_348_residues
PMPPDESALSLLPDHPLAAHNTFGIDARARYAARITHPAQFEALHRDARVATLPHLVLGGGSNVVFTRDFDGLVLLDEIA
GRRVVRDDDDAWYVEAGGGENWHAFVGWTLEHGMAGLENLALIPGTVGAAPIQNIGAYGLEMNAYFDSLVAVELATGRSE
RFDAARCAFGYRDSFFKRDGRGRFAIVSVTFRLPKRWTPRLGYADVTRELEARGISPDAATPRDVFDAVVAIRRAKLPDP
RELGNAGSFFKNPVIDRAQFDALHARAPGIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATGA
DVLALARAIQHDVRTQFGVELEPEPVCL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=334, Percent_Identity=50.5988023952096, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37932; Mature: 37801

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMPPDESALSLLPDHPLAAHNTFGIDARARYAARITHPAQFEALHRDARVATLPHLVLG
CCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHEEEECCCCHHHHHHHHCCHHEECCEEEEC
GGSNVVFTRDFDGLVLLDEIAGRRVVRDDDDAWYVEAGGGENWHAFVGWTLEHGMAGLEN
CCCCEEEEECCCCEEEEEHHCCCEEEECCCCEEEEECCCCCCEEEEEEEEHHHCCCCCCC
LALIPGTVGAAPIQNIGAYGLEMNAYFDSLVAVELATGRSERFDAARCAFGYRDSFFKRD
EEECCCCCCCCCHHHCCCCCEEHHHHHHHEEEEEEECCCCCCCCHHHHHCCCCHHHHHCC
GRGRFAIVSVTFRLPKRWTPRLGYADVTRELEARGISPDAATPRDVFDAVVAIRRAKLPD
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCC
PRELGNAGSFFKNPVIDRAQFDALHARAPGIVSYPQPDGRVKLAAGWLIDRCGWKGRALG
HHHHCCCCCHHCCCCCCHHHHHHHHHCCCCCEECCCCCCCEEEEECEEECCCCCCCCCCC
AAAVHDRQALVLVNRGGATGADVLALARAIQHDVRTQFGVELEPEPVCL
HHEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure 
PMPPDESALSLLPDHPLAAHNTFGIDARARYAARITHPAQFEALHRDARVATLPHLVLG
CCCCCCCHHHHCCCCCCCCCCCCCCCCHHHEEEECCCCHHHHHHHHCCHHEECCEEEEC
GGSNVVFTRDFDGLVLLDEIAGRRVVRDDDDAWYVEAGGGENWHAFVGWTLEHGMAGLEN
CCCCEEEEECCCCEEEEEHHCCCEEEECCCCEEEEECCCCCCEEEEEEEEHHHCCCCCCC
LALIPGTVGAAPIQNIGAYGLEMNAYFDSLVAVELATGRSERFDAARCAFGYRDSFFKRD
EEECCCCCCCCCHHHCCCCCEEHHHHHHHEEEEEEECCCCCCCCHHHHHCCCCHHHHHCC
GRGRFAIVSVTFRLPKRWTPRLGYADVTRELEARGISPDAATPRDVFDAVVAIRRAKLPD
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCC
PRELGNAGSFFKNPVIDRAQFDALHARAPGIVSYPQPDGRVKLAAGWLIDRCGWKGRALG
HHHHCCCCCHHCCCCCCHHHHHHHHHCCCCCEECCCCCCCEEEEECEEECCCCCCCCCCC
AAAVHDRQALVLVNRGGATGADVLALARAIQHDVRTQFGVELEPEPVCL
HHEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA