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The map label for this gene is xerD [H]

Identifier: 161523917

GI number: 161523917

Start: 809496

End: 810446

Strand: Direct

Name: xerD [H]

Synonym: Bmul_0737

Alternate gene names: 161523917

Gene position: 809496-810446 (Clockwise)

Preceding gene: 161523916

Following gene: 161523919

Centisome position: 23.47

GC content: 70.56

Gene sequence:

>951_bases
ATGAGCGAACCGCTGCTGTCTCCCGAAGCCGGCGACGGTACGGCCGCGCCGTCGCCCGCGCTGCTCGCGAGCCGCGCGTC
GATCGACCTGTTCTGCGATGCGCTGTGGCTCGAGCACGGGCTCGCGCGCAACACGCTCGATGCGTACCGGCGCGACCTGA
CGCTGTTTTCGCAATGGCTCGCGGCCACGCACGACGCGGCGCTCGACGCGGCCGACGAAACGATGCTGACCGGCTATATC
GCCGCCCGCAGCGACGGCAAGGCGACGTCGTCGAACCGGCGGCTGTCGGTGTTTCGCCGCTATTACGGCTGGGCCGTGCG
CGAGCATCGCGCGAGTGCCGATCCGACGCTGCGCATCGCGTCCGCGAAGCAGGCGGCGCGGTTCCCGTCGACACTGTCCG
AGGCACAGGTCGAAGCGTTGCTCGGCGCGCCCGACATCGCGACGCCGCTCGGGCTGCGCGATCGCACGATGCTCGAACTG
ATGTACGCGAGCGGGCTGCGCGTGAGCGAGCTCGTCACGCTGAAGACCGTCGAGGTCGGGCTCAACGAAGGCGTCGTGCG
CGTGATGGGCAAGGGCTCGAAGGAGCGGCTCGTGCCGTTCGGCGAGGTCGCGCACGGCTGGATCGAGCGCTATCTGCGCG
AGGCGCGGCCCGCGCTGCTCGGCGCGCGCGCGGCCGACGCGCTGTTCGTGACGGCACGCGGCGACGGGATGACGCGTCAG
CAGTTCTGGAACATCATCAAGCGCCACGCGCAGCACGCGGACGTGCGTGCGCATCTGTCGCCGCACACGCTGCGGCACGC
GTTCGCAACGCATCTGCTGAACCACGGCGCGGACCTGCGCGTCGTGCAGCTGCTGCTCGGCCACGCGGACATCTCGACCA
CGCAGATCTATACGCACGTCGCTCGCGAGCGGCTGCGCACGCTGCACGCGCAGCATCATCCGCGCGGCTGA

Upstream 100 bases:

>100_bases
TCGCCGCGAGCGGGCTCGGCGGTTTCGCGAATCACGACGACGACGGCTATTACCTGAAAGTGAAGCGCTGGCTGCTGGCG
CACGAGGGCGTGCCGTACCG

Downstream 100 bases:

>100_bases
ACGCGGGCTTGCGCTCGAGCTGGGGCTTGCACGCGGGCTCACGCTCCGGCCGTGGTGCACGGGGCGGGCGGCGGCCGTAC
GAGAACGCCTGACGACCGCC

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSEPLLSPEAGDGTAAPSPALLASRASIDLFCDALWLEHGLARNTLDAYRRDLTLFSQWLAATHDAALDAADETMLTGYI
AARSDGKATSSNRRLSVFRRYYGWAVREHRASADPTLRIASAKQAARFPSTLSEAQVEALLGAPDIATPLGLRDRTMLEL
MYASGLRVSELVTLKTVEVGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLREARPALLGARAADALFVTARGDGMTRQ
QFWNIIKRHAQHADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRTLHAQHHPRG

Sequences:

>Translated_316_residues
MSEPLLSPEAGDGTAAPSPALLASRASIDLFCDALWLEHGLARNTLDAYRRDLTLFSQWLAATHDAALDAADETMLTGYI
AARSDGKATSSNRRLSVFRRYYGWAVREHRASADPTLRIASAKQAARFPSTLSEAQVEALLGAPDIATPLGLRDRTMLEL
MYASGLRVSELVTLKTVEVGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLREARPALLGARAADALFVTARGDGMTRQ
QFWNIIKRHAQHADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRTLHAQHHPRG
>Mature_315_residues
SEPLLSPEAGDGTAAPSPALLASRASIDLFCDALWLEHGLARNTLDAYRRDLTLFSQWLAATHDAALDAADETMLTGYIA
ARSDGKATSSNRRLSVFRRYYGWAVREHRASADPTLRIASAKQAARFPSTLSEAQVEALLGAPDIATPLGLRDRTMLELM
YASGLRVSELVTLKTVEVGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLREARPALLGARAADALFVTARGDGMTRQQ
FWNIIKRHAQHADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRTLHAQHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=57.1428571428571, Blast_Score=308, Evalue=2e-85,
Organism=Escherichia coli, GI1790244, Length=294, Percent_Identity=38.4353741496599, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=33.9285714285714, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=27.3255813953488, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34805; Mature: 34674

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLLSPEAGDGTAAPSPALLASRASIDLFCDALWLEHGLARNTLDAYRRDLTLFSQWL
CCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
AATHDAALDAADETMLTGYIAARSDGKATSSNRRLSVFRRYYGWAVREHRASADPTLRIA
HHHHHHHHCCCCHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEH
SAKQAARFPSTLSEAQVEALLGAPDIATPLGLRDRTMLELMYASGLRVSELVTLKTVEVG
HHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHEECC
LNEGVVRVMGKGSKERLVPFGEVAHGWIERYLREARPALLGARAADALFVTARGDGMTRQ
CCCCHHEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHH
QFWNIIKRHAQHADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHV
HHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
ARERLRTLHAQHHPRG
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEPLLSPEAGDGTAAPSPALLASRASIDLFCDALWLEHGLARNTLDAYRRDLTLFSQWL
CCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
AATHDAALDAADETMLTGYIAARSDGKATSSNRRLSVFRRYYGWAVREHRASADPTLRIA
HHHHHHHHCCCCHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEH
SAKQAARFPSTLSEAQVEALLGAPDIATPLGLRDRTMLELMYASGLRVSELVTLKTVEVG
HHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHEECC
LNEGVVRVMGKGSKERLVPFGEVAHGWIERYLREARPALLGARAADALFVTARGDGMTRQ
CCCCHHEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHH
QFWNIIKRHAQHADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHV
HHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
ARERLRTLHAQHHPRG
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]