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The map label for this gene is ygfU [H]

Identifier: 161523871

GI number: 161523871

Start: 758904

End: 760280

Strand: Reverse

Name: ygfU [H]

Synonym: Bmul_0691

Alternate gene names: 161523871

Gene position: 760280-758904 (Counterclockwise)

Preceding gene: 161523875

Following gene: 161523867

Centisome position: 22.05

GC content: 65.5

Gene sequence:

>1377_bases
ATGCAATCGAACACGGTCCATCCGTGCGATGAGGTGTTGCCGACCGGCAAGCTTGTAACGCTCGGCCTGCAGCACGTCCT
CGTCATGTACGCCGGCGCCGTCGCCGTGCCGCTTATCGTCGGCGGCGCGCTGAAGCTGCCGAAAGACCAGATCGCGTTCC
TGATCAGCGCCGATCTGTTTTCGTGCGGCATCGCCACGCTGATCCAGACGCTCGGCCTGTGGATCTTCGGCATCCGCCTG
CCCGTGATCATGGGCTGCACGTTCGCGGCCGTCGGCCCGATGATCGCGATCGGCACGAACCCCGGCCTCGGCATTCTCGA
CATCTTCGGCTCGACGATCGCGGCCGGCATCATCGGCATCGTGCTCGCGCCGATGATCGGCAAGCTGCTGCGGTTCTTCC
CGCCCGTCGTCGTCGGCACCGTGATCTCGGTGATCGGGCTGTCGCTGATGGAAGTCGGGATCAACTGGGCGGCAGGCGGC
GTCGGCAACCCCGAATACGGCAGCCCCGTCTACCTCGGCCTGTCGCTGCTCGTGCTCACGCTGATCCTGCTGATCAACAA
GTACGGCCGCGGCTTCGTCGCCAACATCTCGGTGCTGCTCGGGATCGTCGCGGGCTTCGTGATCGCGTTCGCACTCGGCC
GCGTGAATACCGACGGCGTATCGGTCGCGCCGTGGGTCGGCTTCGTGATGCCGTTCCACTTCGGCTGGCCGCACTTCGAT
CCGCTGTCGATCGCGACGATGGTCACGGTGATGTTCGTCACGTTCATCGAATCGACGGGGATGTTCCTCGCGGTCGGCGA
TATGGTCGAGCGCCCGGTCGATCAGGATCGTCTCGTGCGCGGGCTGCGCGTGGACGGCCTCGGCACGCTGATCGGCGGCA
TCTTCAACTCATTCCCGCATACGTCGTTCTCGCAGAACGTCGGCCTGATCGGCGTGACGGGCGTGAAGAGCCGCTTCGTG
TGCGCGACCGGCGGCGTGATCCTCGTGCTGCTCGGCCTGTTCCCGAAGATGGCGCAGGTCGTCGCCTCGGTGCCGCCGTT
CGTGCTCGGCGGGGCCGGCATCGTGATGTTCGGGATGGTCGCCGCCAACGGCATCAAGGTGCTGTCGAAGGTCGACTTCG
TGAAGAACCACCACAACCTGTTCATCGTCGCGGTCAGCATCGGCATGGGCCTCGTGCCGGTCGTGTCGCCGCACTTCTTC
TCGAAGCTGCCGCCGGCGCTCGCACCGATCCTGCATAGCGGCATCCTGCTCGCGTCCGCGTCGGCCGTGATCCTGAACCT
CGTGTTCAACGGCGTGAAAGGCGAGAAGGACGCGAAATGCGAAATCCGCCGCGCCGGCCACGACTTCGACGGACAGGCCG
TCGACGCGCATCACTGA

Upstream 100 bases:

>100_bases
GAACCAGCAAAGAACGGAATAGAACCCAGTGCTCTTGTGACACCGGTGCATTCCGCATAACTTCGTATCACCCCGAAAAC
AAGATCATGGAGTGAGACAG

Downstream 100 bases:

>100_bases
GCGAACGCATGCGCCGCGACGCGGCGCCGCGATCGACGCAGACGCCACGGGTCGAACCGTGGCGTTTTTTTATTTGGGGT
GGTGGGAAGATCGGGCGTCG

Product: xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MQSNTVHPCDEVLPTGKLVTLGLQHVLVMYAGAVAVPLIVGGALKLPKDQIAFLISADLFSCGIATLIQTLGLWIFGIRL
PVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGIIGIVLAPMIGKLLRFFPPVVVGTVISVIGLSLMEVGINWAAGG
VGNPEYGSPVYLGLSLLVLTLILLINKYGRGFVANISVLLGIVAGFVIAFALGRVNTDGVSVAPWVGFVMPFHFGWPHFD
PLSIATMVTVMFVTFIESTGMFLAVGDMVERPVDQDRLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFV
CATGGVILVLLGLFPKMAQVVASVPPFVLGGAGIVMFGMVAANGIKVLSKVDFVKNHHNLFIVAVSIGMGLVPVVSPHFF
SKLPPALAPILHSGILLASASAVILNLVFNGVKGEKDAKCEIRRAGHDFDGQAVDAHH

Sequences:

>Translated_458_residues
MQSNTVHPCDEVLPTGKLVTLGLQHVLVMYAGAVAVPLIVGGALKLPKDQIAFLISADLFSCGIATLIQTLGLWIFGIRL
PVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGIIGIVLAPMIGKLLRFFPPVVVGTVISVIGLSLMEVGINWAAGG
VGNPEYGSPVYLGLSLLVLTLILLINKYGRGFVANISVLLGIVAGFVIAFALGRVNTDGVSVAPWVGFVMPFHFGWPHFD
PLSIATMVTVMFVTFIESTGMFLAVGDMVERPVDQDRLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFV
CATGGVILVLLGLFPKMAQVVASVPPFVLGGAGIVMFGMVAANGIKVLSKVDFVKNHHNLFIVAVSIGMGLVPVVSPHFF
SKLPPALAPILHSGILLASASAVILNLVFNGVKGEKDAKCEIRRAGHDFDGQAVDAHH
>Mature_458_residues
MQSNTVHPCDEVLPTGKLVTLGLQHVLVMYAGAVAVPLIVGGALKLPKDQIAFLISADLFSCGIATLIQTLGLWIFGIRL
PVIMGCTFAAVGPMIAIGTNPGLGILDIFGSTIAAGIIGIVLAPMIGKLLRFFPPVVVGTVISVIGLSLMEVGINWAAGG
VGNPEYGSPVYLGLSLLVLTLILLINKYGRGFVANISVLLGIVAGFVIAFALGRVNTDGVSVAPWVGFVMPFHFGWPHFD
PLSIATMVTVMFVTFIESTGMFLAVGDMVERPVDQDRLVRGLRVDGLGTLIGGIFNSFPHTSFSQNVGLIGVTGVKSRFV
CATGGVILVLLGLFPKMAQVVASVPPFVLGGAGIVMFGMVAANGIKVLSKVDFVKNHHNLFIVAVSIGMGLVPVVSPHFF
SKLPPALAPILHSGILLASASAVILNLVFNGVKGEKDAKCEIRRAGHDFDGQAVDAHH

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=461, Percent_Identity=27.3318872017354, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI40316845, Length=461, Percent_Identity=27.3318872017354, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI44680145, Length=476, Percent_Identity=25.8403361344538, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI44680143, Length=480, Percent_Identity=25.625, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI222080105, Length=510, Percent_Identity=23.7254901960784, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI222080107, Length=521, Percent_Identity=23.4165067178503, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI87082181, Length=441, Percent_Identity=59.1836734693878, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1790087, Length=447, Percent_Identity=30.8724832214765, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI87082178, Length=457, Percent_Identity=29.1028446389497, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788843, Length=386, Percent_Identity=28.7564766839378, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87081818, Length=409, Percent_Identity=30.0733496332518, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17558856, Length=504, Percent_Identity=25.7936507936508, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17541904, Length=464, Percent_Identity=23.0603448275862, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17542262, Length=454, Percent_Identity=25.5506607929515, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17542260, Length=195, Percent_Identity=29.7435897435897, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71993493, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356175, Length=500, Percent_Identity=25, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47843; Mature: 47843

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]