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The map label for this gene is corC [H]

Identifier: 161523781

GI number: 161523781

Start: 658806

End: 659693

Strand: Reverse

Name: corC [H]

Synonym: Bmul_0601

Alternate gene names: 161523781

Gene position: 659693-658806 (Counterclockwise)

Preceding gene: 161523782

Following gene: 161523780

Centisome position: 19.13

GC content: 63.29

Gene sequence:

>888_bases
ATGAACGATTCGTATCCCAGTCGAAAGCCAACCGACAAACCGCAAGAAAAGCGCTCGCTGCTCGAGCGCCTGACCGACTT
CATCTCGCCCGAGCCCGAATCCCGCGGCGAGCTGCTCGAAATCCTCCAGGACGCGCACGAACGCAACCTGATCGACGCCG
ATTCGCTGTCGATGATCGAAGGCGTATTCCAGGTATCCGACCTGTGCGCACGCGACATCATGGTGCCGCGCGCCCAGATG
GACGCGATCAACATCGCCGACAAGCCCGAGGATTTCATCCCGTTCGTCCTCGAAAAGGCGCACTCGCGCTACCCCGTGTA
CGAGGAGAACCGCGACAACGTGATCGGCGTGCTGCTCGCGAAGGACCTGCTGCGCTTCTATGCGGAAGAGGAATTCGACG
TGCGCGGGATGCTGCGCCCGGCCGTGTTCATTCCCGAATCGAAGCGCCTGAATGTGCTGCTGCACGACTTCCGCGTGAAC
CGCAACCACCTTGCGATCGTCGTCGACGAATACGGCGGCGTCGCGGGCCTGATTACGATCGAGGACGTGCTCGAGCAGAT
CGTCGGCGACATCGAGGACGAATACGACTTCGACGAGGAAGCCGGCAACATCATCTCGGGGCCGGACGGCCGCTACCGCG
TGCGCGCGCTGACCGAGATCGAGCAGTTCAACGAGGTGTTCGGCACCGATTTCTCCGACGAGGAGGTCGACACGATCGGC
GGGCTGATCACCCATCATTTCGGCCGCGTGCCGCACCGCGGCGAAAAGCTGCAGCTCGGCAACCTCGTATTCGAGATCCA
GCGCGGCGACGCGCGCCAGATTCACGTGCTGCTGGTGCGCCGCAACCCGCTCGCGAGCCGCCGCGCCGAAACCTCGCACG
AGGACTGA

Upstream 100 bases:

>100_bases
CATCGGCCGGACGGCCGGCGCGACACGGACCTGCCATCCCCTTGGTGTATCCTTGCCTACTCCGTGACAGCGCGCCCCGG
CACGACCCGGGCGCACCACC

Downstream 100 bases:

>100_bases
TCCAACCGTCGCGCATCGGCCGCGCCCTTTCCAACCGCTTCGCCCACTTCCGCTTCACATGGACGACCCGATCCCGTCCC
GCCCGGCTGGCGGCATTCCC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNDSYPSRKPTDKPQEKRSLLERLTDFISPEPESRGELLEILQDAHERNLIDADSLSMIEGVFQVSDLCARDIMVPRAQM
DAINIADKPEDFIPFVLEKAHSRYPVYEENRDNVIGVLLAKDLLRFYAEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVN
RNHLAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDEEAGNIISGPDGRYRVRALTEIEQFNEVFGTDFSDEEVDTIG
GLITHHFGRVPHRGEKLQLGNLVFEIQRGDARQIHVLLVRRNPLASRRAETSHED

Sequences:

>Translated_295_residues
MNDSYPSRKPTDKPQEKRSLLERLTDFISPEPESRGELLEILQDAHERNLIDADSLSMIEGVFQVSDLCARDIMVPRAQM
DAINIADKPEDFIPFVLEKAHSRYPVYEENRDNVIGVLLAKDLLRFYAEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVN
RNHLAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDEEAGNIISGPDGRYRVRALTEIEQFNEVFGTDFSDEEVDTIG
GLITHHFGRVPHRGEKLQLGNLVFEIQRGDARQIHVLLVRRNPLASRRAETSHED
>Mature_295_residues
MNDSYPSRKPTDKPQEKRSLLERLTDFISPEPESRGELLEILQDAHERNLIDADSLSMIEGVFQVSDLCARDIMVPRAQM
DAINIADKPEDFIPFVLEKAHSRYPVYEENRDNVIGVLLAKDLLRFYAEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVN
RNHLAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDEEAGNIISGPDGRYRVRALTEIEQFNEVFGTDFSDEEVDTIG
GLITHHFGRVPHRGEKLQLGNLVFEIQRGDARQIHVLLVRRNPLASRRAETSHED

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=209, Percent_Identity=31.1004784688995, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI94681046, Length=179, Percent_Identity=28.4916201117318, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI40068053, Length=179, Percent_Identity=27.3743016759777, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI40068055, Length=179, Percent_Identity=27.3743016759777, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786879, Length=265, Percent_Identity=43.3962264150943, Blast_Score=212, Evalue=2e-56,
Organism=Escherichia coli, GI145693175, Length=273, Percent_Identity=27.4725274725275, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87082033, Length=244, Percent_Identity=26.6393442622951, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788119, Length=231, Percent_Identity=29.4372294372294, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790664, Length=232, Percent_Identity=25.4310344827586, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33736; Mature: 33736

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSYPSRKPTDKPQEKRSLLERLTDFISPEPESRGELLEILQDAHERNLIDADSLSMIE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
GVFQVSDLCARDIMVPRAQMDAINIADKPEDFIPFVLEKAHSRYPVYEENRDNVIGVLLA
HHHHHHHHHHHHHCCCCHHHCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHH
KDLLRFYAEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVNRNHLAIVVDEYGGVAGLITI
HHHHHHHCCCCCCHHHCCCCEEECCCCCCCEEEEEEEEECCCEEEEEEECCCCEEEEEEH
EDVLEQIVGDIEDEYDFDEEAGNIISGPDGRYRVRALTEIEQFNEVFGTDFSDEEVDTIG
HHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHH
GLITHHFGRVPHRGEKLQLGNLVFEIQRGDARQIHVLLVRRNPLASRRAETSHED
HHHHHHHCCCCCCCCEEEECCEEEEEECCCCCEEEEEEEECCCCHHHHCCCCCCC
>Mature Secondary Structure
MNDSYPSRKPTDKPQEKRSLLERLTDFISPEPESRGELLEILQDAHERNLIDADSLSMIE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
GVFQVSDLCARDIMVPRAQMDAINIADKPEDFIPFVLEKAHSRYPVYEENRDNVIGVLLA
HHHHHHHHHHHHHCCCCHHHCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHH
KDLLRFYAEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVNRNHLAIVVDEYGGVAGLITI
HHHHHHHCCCCCCHHHCCCCEEECCCCCCCEEEEEEEEECCCEEEEEEECCCCEEEEEEH
EDVLEQIVGDIEDEYDFDEEAGNIISGPDGRYRVRALTEIEQFNEVFGTDFSDEEVDTIG
HHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHH
GLITHHFGRVPHRGEKLQLGNLVFEIQRGDARQIHVLLVRRNPLASRRAETSHED
HHHHHHHCCCCCCCCEEEECCEEEEEECCCCCEEEEEEEECCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]