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The map label for this gene is hisC2 [H]

Identifier: 161523690

GI number: 161523690

Start: 559085

End: 560152

Strand: Reverse

Name: hisC2 [H]

Synonym: Bmul_0510

Alternate gene names: 161523690

Gene position: 560152-559085 (Counterclockwise)

Preceding gene: 161523691

Following gene: 161523688

Centisome position: 16.24

GC content: 68.82

Gene sequence:

>1068_bases
GTGAGCCGTTACTGGAGCGATGTCGTTCAGCAACTCGTGCCTTACGTGCCGGGCGAGCAGCCCGCGCTCGCACACCCCGT
CAAGCTGAACACCAACGAGAATCCCTATCCGCCGTCGCCGCGCGTCGTCGCGGCGATCGCGCGCGAACTCGGCGCGAACG
GCGACACGCTGCGCCGCTACCCCGACCCGCTCGCCCGCGCGCTGCGCGAAACGGTCGCCGCGCACCATCGCCTCCGTCCC
GAGCAGGTGTTCGTCGGCAACGGCTCCGACGAAGTGCTCGCGCACACGTTCCAGGCGCTGCTGAAGCACGACCGGCCGCT
GCGCTTTCCCGACATCACGTACAGCTTCTATCCGACCTATGCGCGGCTGTACGGCGTCGACACCCGCACCGTGCCGCTCG
CGGACGACTTCTCGATCCGCGTCGACGACTATCTCGACGACGGCGGCGGCGTGCTGTTTCCGAACCCGAATGCGCCGACC
GGCCGCGCGCTGCCGCTCGCGGACATCGAGCGGATCGCAGCGGCCAATCCGTCGTCGGTCGTCGTGATCGACGAAGCGTA
TGTCGATTTCGGCGCGCAGTCGGCGATTGCGCTGATCGACCGCTATCCGAACCTGCTCGTCGTGCACACGACGTCGAAGG
CACGCTCGCTCGCGGGCATGCGCGTCGGCTTCGCGTTCGGCGACGCGGCGCTGATCGAAGCGCTGAACCGCGTGAAGGAC
AGCTTCAACTCGTACCCGCTCGACCGGCTCGCGCAGGTGGCCGCGCAGGCCGCATACGAAGACGACGCGTACTTCGTGTC
GACCTGCGCGCGCGTCGTCGACAGCCGCACGCGGCTCACGCAGGCACTCGACGCGCTCGGCTTCGACGTCGTGCCGTCGG
CCGCGAACTTCGTGTTCGCGCGCCATCCGGCGCACGACGCGGGCACGCTCGCGGCGAAGCTGAAGGAACGGGAAATTTTC
GTGCGGCATTTCCGGCTGCCGCGCATCGACCAGCACTTGCGCATCACCGTCGGCACCGACGCCGAATGCGAGGCGCTCGT
GGCCGCCTTGCGCGAGCTGCTCGGCTGA

Upstream 100 bases:

>100_bases
GCCGCGCCGGCTGCCGACATGCGCGGCCGCACTGGCGCGACGCGCGCCGCGGCGTGCAACATGCGGTACTCTCGTTGTTT
TGCCCGTCAGGAGCCAAGCG

Downstream 100 bases:

>100_bases
AGACCGCGGGCGGCACGGCAACGCCGCCCGGGAAGACGCGGCGCGCACCGGCGCGCCGCTTGCTGCGCTTACTGCGCGTC
GCCGGTCGCGGCGATCAGCG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSRYWSDVVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGANGDTLRRYPDPLARALRETVAAHHRLRP
EQVFVGNGSDEVLAHTFQALLKHDRPLRFPDITYSFYPTYARLYGVDTRTVPLADDFSIRVDDYLDDGGGVLFPNPNAPT
GRALPLADIERIAAANPSSVVVIDEAYVDFGAQSAIALIDRYPNLLVVHTTSKARSLAGMRVGFAFGDAALIEALNRVKD
SFNSYPLDRLAQVAAQAAYEDDAYFVSTCARVVDSRTRLTQALDALGFDVVPSAANFVFARHPAHDAGTLAAKLKEREIF
VRHFRLPRIDQHLRITVGTDAECEALVAALRELLG

Sequences:

>Translated_355_residues
MSRYWSDVVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGANGDTLRRYPDPLARALRETVAAHHRLRP
EQVFVGNGSDEVLAHTFQALLKHDRPLRFPDITYSFYPTYARLYGVDTRTVPLADDFSIRVDDYLDDGGGVLFPNPNAPT
GRALPLADIERIAAANPSSVVVIDEAYVDFGAQSAIALIDRYPNLLVVHTTSKARSLAGMRVGFAFGDAALIEALNRVKD
SFNSYPLDRLAQVAAQAAYEDDAYFVSTCARVVDSRTRLTQALDALGFDVVPSAANFVFARHPAHDAGTLAAKLKEREIF
VRHFRLPRIDQHLRITVGTDAECEALVAALRELLG
>Mature_354_residues
SRYWSDVVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGANGDTLRRYPDPLARALRETVAAHHRLRPE
QVFVGNGSDEVLAHTFQALLKHDRPLRFPDITYSFYPTYARLYGVDTRTVPLADDFSIRVDDYLDDGGGVLFPNPNAPTG
RALPLADIERIAAANPSSVVVIDEAYVDFGAQSAIALIDRYPNLLVVHTTSKARSLAGMRVGFAFGDAALIEALNRVKDS
FNSYPLDRLAQVAAQAAYEDDAYFVSTCARVVDSRTRLTQALDALGFDVVPSAANFVFARHPAHDAGTLAAKLKEREIFV
RHFRLPRIDQHLRITVGTDAECEALVAALRELLG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=355, Percent_Identity=31.830985915493, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788722, Length=240, Percent_Identity=30.4166666666667, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322075, Length=362, Percent_Identity=27.3480662983425, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39042; Mature: 38910

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYWSDVVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGANGDTLRRY
CCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHCC
PDPLARALRETVAAHHRLRPEQVFVGNGSDEVLAHTFQALLKHDRPLRFPDITYSFYPTY
CCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCHH
ARLYGVDTRTVPLADDFSIRVDDYLDDGGGVLFPNPNAPTGRALPLADIERIAAANPSSV
HHHCCCCCCEEECCCCCEEEEECEECCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCEE
VVIDEAYVDFGAQSAIALIDRYPNLLVVHTTSKARSLAGMRVGFAFGDAALIEALNRVKD
EEEEHHHHCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHEEEHHHCHHHHHHHHHHHHH
SFNSYPLDRLAQVAAQAAYEDDAYFVSTCARVVDSRTRLTQALDALGFDVVPSAANFVFA
HHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
RHPAHDAGTLAAKLKEREIFVRHFRLPRIDQHLRITVGTDAECEALVAALRELLG
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHC
>Mature Secondary Structure 
SRYWSDVVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGANGDTLRRY
CHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHCC
PDPLARALRETVAAHHRLRPEQVFVGNGSDEVLAHTFQALLKHDRPLRFPDITYSFYPTY
CCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCHH
ARLYGVDTRTVPLADDFSIRVDDYLDDGGGVLFPNPNAPTGRALPLADIERIAAANPSSV
HHHCCCCCCEEECCCCCEEEEECEECCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCEE
VVIDEAYVDFGAQSAIALIDRYPNLLVVHTTSKARSLAGMRVGFAFGDAALIEALNRVKD
EEEEHHHHCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHEEEHHHCHHHHHHHHHHHHH
SFNSYPLDRLAQVAAQAAYEDDAYFVSTCARVVDSRTRLTQALDALGFDVVPSAANFVFA
HHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
RHPAHDAGTLAAKLKEREIFVRHFRLPRIDQHLRITVGTDAECEALVAALRELLG
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA