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The map label for this gene is gylR [H]

Identifier: 161523571

GI number: 161523571

Start: 432551

End: 433417

Strand: Reverse

Name: gylR [H]

Synonym: Bmul_0391

Alternate gene names: 161523571

Gene position: 433417-432551 (Counterclockwise)

Preceding gene: 161523578

Following gene: 161523570

Centisome position: 12.57

GC content: 69.67

Gene sequence:

>867_bases
ATGTCCGCCAGCCCGCTTCCCGACGACGATCTCGCCGATTCCGATACCGACGACACCGCAGCCGGGGAGCACGGCGAGAA
GGTGCGTTCCGGCATCCAGTCGATCGAGGTCGGCTTCCGGCTGCTCGACGTACTGACGAGCGAGCCGCGCGCGATGATGC
TGCGCGATCTCGCGCAGCGCGCGGGCATGAGCCCTGCGAAGGCGCACCGCTATCTCGTGAGCTTCCTGCGGCTCGGCGTC
GTGTCGCAGGACCCTGTGTCGGGCCGCTACGAGCTCGGCGGCTTCGCGCTGCAGATGGGGCTCGCGCGGCTCGCGCGCGT
CGACGGCGTGAAGCTCGCGCGTATCGCGCTGACCGAATTCCGCGATCGGCTCGACCAGACGGTCGGCATCGCCGTATGGG
GCAATCAGGGGCCGACGATCGTGCACTGGATGGAATCGAGCCATCCGGCGAAGGCGTCGCTGAAGCTCGGCGACGTGATG
CCGCTGCTCGGCTCCGCGACGGGCCTGCTGTTCGCTGCCTATCTGCCGCGCAGCAAGACCGCCGCGATGCTCGAGCGCGA
ACTCGCCGACACGCGGCGCTCGCCGCATCACGGCGGCCCGCGCACGCTCGACGAGGTCGAAGCGATGCTCGCGGACGTGC
GCGCGCACGAGGCCGCGCGTGTCGAAGGCATGCTGCTGCCGACCATTCACGCGTTCTGCATGCCGGTGTTCGATGCGGTC
GGCGAACTCGCGCTCGGCATCGTCGCACTCGGCCACGAAGGCACGTTCGACATCGCGTGGGGCGGCGAGATCGACACCGC
CCTGCGCGCATGCGCGCGCAAGCTGTCGTACGAACTCGGCTATAGTCCGGTCGCGCGCGACGCCTGA

Upstream 100 bases:

>100_bases
TGGAGGGAATCTATTTTACGATGGTGAATCCGCGCGGCGCGGGAACCTATCGCGCGCCGCTTCCGTCCCGATCCTTGCCG
CGTTTCCGCGCCCTGCTTCC

Downstream 100 bases:

>100_bases
TGCGCGCGACGCGCCGCGAACGCGCGGCGCATCCGACGGTCCGACATGCGATGACGCGCGCGTCGCGCGTCCCAACCCCG
TTCCGACTGCCGATGCCGCA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSASPLPDDDLADSDTDDTAAGEHGEKVRSGIQSIEVGFRLLDVLTSEPRAMMLRDLAQRAGMSPAKAHRYLVSFLRLGV
VSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTEFRDRLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVM
PLLGSATGLLFAAYLPRSKTAAMLERELADTRRSPHHGGPRTLDEVEAMLADVRAHEAARVEGMLLPTIHAFCMPVFDAV
GELALGIVALGHEGTFDIAWGGEIDTALRACARKLSYELGYSPVARDA

Sequences:

>Translated_288_residues
MSASPLPDDDLADSDTDDTAAGEHGEKVRSGIQSIEVGFRLLDVLTSEPRAMMLRDLAQRAGMSPAKAHRYLVSFLRLGV
VSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTEFRDRLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVM
PLLGSATGLLFAAYLPRSKTAAMLERELADTRRSPHHGGPRTLDEVEAMLADVRAHEAARVEGMLLPTIHAFCMPVFDAV
GELALGIVALGHEGTFDIAWGGEIDTALRACARKLSYELGYSPVARDA
>Mature_287_residues
SASPLPDDDLADSDTDDTAAGEHGEKVRSGIQSIEVGFRLLDVLTSEPRAMMLRDLAQRAGMSPAKAHRYLVSFLRLGVV
SQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTEFRDRLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMP
LLGSATGLLFAAYLPRSKTAAMLERELADTRRSPHHGGPRTLDEVEAMLADVRAHEAARVEGMLLPTIHAFCMPVFDAVG
ELALGIVALGHEGTFDIAWGGEIDTALRACARKLSYELGYSPVARDA

Specific function: May be an activator protein for the gylABX operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=237, Percent_Identity=24.8945147679325, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786468, Length=154, Percent_Identity=25.3246753246753, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30996; Mature: 30865

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASPLPDDDLADSDTDDTAAGEHGEKVRSGIQSIEVGFRLLDVLTSEPRAMMLRDLAQR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AGMSPAKAHRYLVSFLRLGVVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTEF
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RDRLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMPLLGSATGLLFAAYLPRSKT
HHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHH
AAMLERELADTRRSPHHGGPRTLDEVEAMLADVRAHEAARVEGMLLPTIHAFCMPVFDAV
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GELALGIVALGHEGTFDIAWGGEIDTALRACARKLSYELGYSPVARDA
HHHHHHHHEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SASPLPDDDLADSDTDDTAAGEHGEKVRSGIQSIEVGFRLLDVLTSEPRAMMLRDLAQR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AGMSPAKAHRYLVSFLRLGVVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTEF
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RDRLDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMPLLGSATGLLFAAYLPRSKT
HHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHH
AAMLERELADTRRSPHHGGPRTLDEVEAMLADVRAHEAARVEGMLLPTIHAFCMPVFDAV
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GELALGIVALGHEGTFDIAWGGEIDTALRACARKLSYELGYSPVARDA
HHHHHHHHEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3225846; 12000953 [H]