Click here to switch to the map view.

The map label for this gene is ribH [H]

Identifier: 161511188

GI number: 161511188

Start: 5604758

End: 5605252

Strand: Reverse

Name: ribH [H]

Synonym: BT_4253

Alternate gene names: 161511188

Gene position: 5605252-5604758 (Counterclockwise)

Preceding gene: 29349662

Following gene: 29349660

Centisome position: 89.54

GC content: 38.59

Gene sequence:

>495_bases
ATGGCAACAGCATACCATAACTTATCCGAATACGATTTCAACTCTGTACCAAACGCTGAAAACATGAAATTCGGCATCGT
CGTATCCGAATGGAATTTCAATATTACCGGAGCCTTATTGAACGGCGCAGTCAATACATTAAAAAAACATGGAGTGAAAG
ATGAAAATATTCTGGTAAAAACTGTACCGGGAAGTTTCGAACTAACTTTCGGCGCCAATCAAATGATGGAAAATTGCGAT
GTGGATGCAATTATTGCAATCGGTTGTGTAATTAAAGGAGATACTCCACATTTTGATTATGTTTGTATGGGAGCGACTCA
AGGAATTACCGAATTAAACGCAACTGGCGACATACCAGTCATTTACGGATTAATTACCACCAATACAATGGAGCAAGCAG
AGGATCGTGCCGGTGGCAAACTGGGTAACAAAGGAGATGAATGTGCAATTTCTGCAATAAAAATGATCGATTTTGTTTGG
AGTTTAAATAAATAG

Upstream 100 bases:

>100_bases
CAATATGTACTAATGCAATTATGCGAAGCTACCGTGAAATCCGTGTAATCCGTGCCTTTTTAAAATCATGTATTTATAAC
CCACTTTAATTACTACAATT

Downstream 100 bases:

>100_bases
TTGTATCTTTGCACCGCAATTGAGAAACAAACCTCCTCAAAAGCACAAAAGGGCAAATACCAGAGTGGCCAAATGGGGCA
GACTGTAAATCTGCTGGCTT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MATAYHNLSEYDFNSVPNAENMKFGIVVSEWNFNITGALLNGAVNTLKKHGVKDENILVKTVPGSFELTFGANQMMENCD
VDAIIAIGCVIKGDTPHFDYVCMGATQGITELNATGDIPVIYGLITTNTMEQAEDRAGGKLGNKGDECAISAIKMIDFVW
SLNK

Sequences:

>Translated_164_residues
MATAYHNLSEYDFNSVPNAENMKFGIVVSEWNFNITGALLNGAVNTLKKHGVKDENILVKTVPGSFELTFGANQMMENCD
VDAIIAIGCVIKGDTPHFDYVCMGATQGITELNATGDIPVIYGLITTNTMEQAEDRAGGKLGNKGDECAISAIKMIDFVW
SLNK
>Mature_163_residues
ATAYHNLSEYDFNSVPNAENMKFGIVVSEWNFNITGALLNGAVNTLKKHGVKDENILVKTVPGSFELTFGANQMMENCDV
DAIIAIGCVIKGDTPHFDYVCMGATQGITELNATGDIPVIYGLITTNTMEQAEDRAGGKLGNKGDECAISAIKMIDFVWS
LNK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=144, Percent_Identity=42.3611111111111, Blast_Score=124, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324429, Length=151, Percent_Identity=35.0993377483444, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 17729; Mature: 17598

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAYHNLSEYDFNSVPNAENMKFGIVVSEWNFNITGALLNGAVNTLKKHGVKDENILVK
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCCCEEEE
TVPGSFELTFGANQMMENCDVDAIIAIGCVIKGDTPHFDYVCMGATQGITELNATGDIPV
ECCCCEEEEECHHHHHHHCCCCEEEEEEEEEECCCCCCCEEEECCCCCCEECCCCCCCEE
IYGLITTNTMEQAEDRAGGKLGNKGDECAISAIKMIDFVWSLNK
EEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATAYHNLSEYDFNSVPNAENMKFGIVVSEWNFNITGALLNGAVNTLKKHGVKDENILVK
CCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCCCEEEE
TVPGSFELTFGANQMMENCDVDAIIAIGCVIKGDTPHFDYVCMGATQGITELNATGDIPV
ECCCCEEEEECHHHHHHHCCCCEEEEEEEEEECCCCCCCEEEECCCCCCEECCCCCCCEE
IYGLITTNTMEQAEDRAGGKLGNKGDECAISAIKMIDFVWSLNK
EEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA