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The map label for this gene is luxS [H]

Identifier: 161511080

GI number: 161511080

Start: 387334

End: 387807

Strand: Direct

Name: luxS [H]

Synonym: BB0377

Alternate gene names: 161511080

Gene position: 387334-387807 (Clockwise)

Preceding gene: 15594721

Following gene: 15594744

Centisome position: 42.53

GC content: 30.59

Gene sequence:

>474_bases
ATGAAAAAAATAACAAGCTTTACAATAGATCATACAAAACTCAACCCTGGCATATATGTCTCAAGAAAAGATACCTTTGA
AAATGTAATATTTACTACAATAGACATTAGAATCAAAGCTCCCAACATCGAACCAATAATTGAAAACGCAGCAATACATA
CAATAGAGCACATAGGAGCTACTTTACTTAGAAATAATGAAGTTTGGACCGAAAAAATAGTATATTTTGGCCCTATGGGA
TGCAGAACTGGTTTTTACTTAATAATTTTTGGAGACTATGAAAGTAAAGATCTTGTTGACTTAGTCTCATGGCTTTTTTC
CGAAATCGTAAATTTTTCAGAACCTATCCCAGGCGCAAGTGATAAGGAATGCGGAAATTACAAAGAACATAACCTTGATA
TGGCTAAATATGAATCTTCTAAATACTTACAAATATTAAACAATATTAAAGAAGAAAATTTAAAATATCCTTAG

Upstream 100 bases:

>100_bases
CCATATATCTTAAAACTTGCACTTATGGTCATTTTGGAAAAAATGAATTTGAATGGGAAAAATTAGATTTTGTAAAAAAA
ATACAAACAGCGCTAAAAAA

Downstream 100 bases:

>100_bases
CTCATAAAATTTACAAAATAGAAAGTATTTCGCTTTCATTTTTTGTTGCTACATCAAACTGAAAAATAAATCCTAATGTT
ATTTTATGCATTTGATTTAA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGATLLRNNEVWTEKIVYFGPMG
CRTGFYLIIFGDYESKDLVDLVSWLFSEIVNFSEPIPGASDKECGNYKEHNLDMAKYESSKYLQILNNIKEENLKYP

Sequences:

>Translated_157_residues
MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGATLLRNNEVWTEKIVYFGPMG
CRTGFYLIIFGDYESKDLVDLVSWLFSEIVNFSEPIPGASDKECGNYKEHNLDMAKYESSKYLQILNNIKEENLKYP
>Mature_157_residues
MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGATLLRNNEVWTEKIVYFGPMG
CRTGFYLIIFGDYESKDLVDLVSWLFSEIVNFSEPIPGASDKECGNYKEHNLDMAKYESSKYLQILNNIKEENLKYP

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=144, Percent_Identity=31.9444444444444, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 18098; Mature: 18098

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGA
CCCCCEEEEECEECCCCEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
TLLRNNEVWTEKIVYFGPMGCRTGFYLIIFGDYESKDLVDLVSWLFSEIVNFSEPIPGAS
HHHCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCC
DKECGNYKEHNLDMAKYESSKYLQILNNIKEENLKYP
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGA
CCCCCEEEEECEECCCCEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
TLLRNNEVWTEKIVYFGPMGCRTGFYLIIFGDYESKDLVDLVSWLFSEIVNFSEPIPGAS
HHHCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCC
DKECGNYKEHNLDMAKYESSKYLQILNNIKEENLKYP
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA