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The map label for this gene is murG [H]

Identifier: 161509585

GI number: 161509585

Start: 1458377

End: 1459447

Strand: Reverse

Name: murG [H]

Synonym: USA300HOU_1355

Alternate gene names: 161509585

Gene position: 1459447-1458377 (Counterclockwise)

Preceding gene: 161509586

Following gene: 161509584

Centisome position: 50.8

GC content: 30.07

Gene sequence:

>1071_bases
ATGACGAAAATCGCATTTACCGGAGGGGGAACAGTTGGACACGTATCAGTAAATTTAAGTTTAATTCCAACTGCATTATC
ACAAGGTTATGAAGCGCTTTATATTGGTTCTAAAAATGGTATTGAAAGAGAAATGATTGAATCACAACTACCAGAAATTA
AGTATTATCCTATTTCGAGTGGTAAATTAAGAAGATATATTTCTTTAGAAAATGCCAAAGACGTATTTAAAGTATTGAAA
GGTATTCTTGATGCTCGTAAAGTTTTGAAAAAAGAAAAACCTGATCTATTATTTTCAAAAGGTGGATTTGTATCTGTGCC
TGTTGTTATTGCAGCCAAATCATTAAATATACCAACTCTTATTCATGAATCTGACTTAACACCAGGATTAGCGAATAAGA
TAGCACTTAAATTTGCCAAGAAAATATATACAACATTTGAAGAAACGCTAAACTACTTACCTAAAGAGAAAGCTGATTTT
ATTGGAGCAACAATTCGAGAAGATTTAAAAAATGGTAATGCACATAATGGTTATCAATTAACAGGCTTTAATGAAAATAA
AAAAGTTTTACTCGTTATGGGTGGAAGCTTAGGAAGTAAAAAATTAAATAGCATTATTCGCGAAAACTTAGATGCATTAT
TACAACAATATCAAGTGATACATTTAACTGGTAAAGGATTAAAAGATGCTCAAGTTAAAAAATCAGGATATATACAATAT
GAATTTGTTAAAGAGGATTTAACAGATTTATTAGCAATTACGGATACAGTAATAAGTAGAGCTGGATCAAATGCGATTTA
TGAGTTCTTAACATTACGTATACCAATGTTATTAGTACCATTAGGTTTAGATCAATCCCGAGGCGACCAAATTGACAATG
CAAATCATTTTGCTGATAAAGGATATGCTAAAGCGATTGATGAAGAACAATTAACAGCACAAATTTTATTACAAGAACTA
AATGAAATGGAACAGGAAAGAACTCGAATTATCAATAATATGAAATCGTATGAACAAAGTTATACGAAAGAAGCTTTATT
TGATAAGATGATTAAAGACGCATTGAATTAA

Upstream 100 bases:

>100_bases
TTCATAAGGTCGGTGAACAATTAATGGAATATCCGCCATATGATAAAGGTGAACCATTTTATGCATATTATAAAAATTTA
AAAGAATAGAGGTAATATTA

Downstream 100 bases:

>100_bases
TGGGGGGTAATGCTTTATGAGTCAATGGAAACGTATCTCTTTGCTCATCGTTTTTACATTGGTTTTTGGAATTATCGCGT
TTTTCCACGAATCAAGACTT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLK
GILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTLIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADF
IGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQY
EFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKAIDEEQLTAQILLQEL
NEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN

Sequences:

>Translated_356_residues
MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLK
GILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTLIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADF
IGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQY
EFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKAIDEEQLTAQILLQEL
NEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
>Mature_355_residues
TKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLKG
ILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTLIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFI
GATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQYE
FVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKAIDEEQLTAQILLQELN
EMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=330, Percent_Identity=27.2727272727273, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39697; Mature: 39566

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISS
CCEEEEECCCEEEEEEEEEEEEHHHHHCCCEEEEECCCCCCHHHHHHHHCCCEEEEECCC
GKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTL
CCEEHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEECCEEEEECCCCCEE
IHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFIGATIREDLKNGNAHNGYQL
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEE
TGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQY
EEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHCCCEEE
EFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADK
EEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHCC
GYAKAIDEEQLTAQILLQELNEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
CHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISS
CEEEEECCCEEEEEEEEEEEEHHHHHCCCEEEEECCCCCCHHHHHHHHCCCEEEEECCC
GKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTL
CCEEHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEECCEEEEECCCCCEE
IHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFIGATIREDLKNGNAHNGYQL
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEE
TGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQY
EEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHCCCEEE
EFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADK
EEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHCC
GYAKAIDEEQLTAQILLQELNEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
CHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA